Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Francesca Crasto"'
1
Sensitive Replicate Real-Time Quantitative PCR of BCR-ABL Shows Deep Molecular Responses in Long-Term Post–Allogeneic Stem Cell Transplantation Chronic Myeloid Leukemia Patients
Autor: Filomena Daraio, Francesca Crasto, Yulia Volchek, Arnon Nagler, Ninette Amariglio, Roberta Lorenzatti, Giuseppe Saglio, Maya Koren-Michowitz, Enrico Gottardi, Avichai Shimoni
Publikováno v: Biology of Blood and Marrow Transplantation. 21:1852-1855
Real-time quantitative PCR (RT-qPCR) is commonly used for follow-up of chronic myeloid leukemia (CML) patients treated with tyrosine kinase inhibitors, but its current sensitivity does not allow detection of very low BCR-ABL levels. Therefore RT-qPCR
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225a878eda29f70486b86d98b663c3ed
https://doi.org/10.1016/j.bbmt.2015.06.018
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2
Non genomic loss of function of tumor suppressors in CML: BCR-ABL promotes IκBα mediated p53 nuclear exclusion
Autor: Francesca Crasto, Enrico Gottardi, Giuseppe Saglio, Alessandro Morotti, Sabrina Crivellaro, Riccardo Taulli, Ubaldo Familiari, Rocco Piazza, Mauro Papotti, Giovanna Carrà, Sara Redaelli, Angelo Guerrasio, Cristina Panuzzo, Davide Torti, Alessandro Volpengo
Publikováno v: Oncotarget
Tumor suppressor function can be modulated by subtle variation of expression levels, proper cellular compartmentalization and post-translational modifications, such as phosphorylation, acetylation and sumoylation. The non-genomic loss of function of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befa789e57efb9a76bde92c9fd7f3d2a
https://doi.org/10.18632/oncotarget.4611
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4
Clinical significance ofTFR2andEPORexpression in bone marrow cells in myelodysplastic syndromes
Autor: Augusta Di Savino Valentina Gaidano Antonietta Palmieri Francesca Crasto Alessandro Volpengo Roberta Lorenzatti Patrizia Scaravaglio Alessandro Manello Paolo Nicoli Enrico Gottardi Giuseppe Saglio Daniela Cilloni Marco De Gobbi
Publikováno v: British journal of haematology
176 (2017): 491–495.
info:cnr-pdr/source/autori:Augusta Di Savino Valentina Gaidano Antonietta Palmieri Francesca Crasto Alessandro Volpengo Roberta Lorenzatti Patrizia Scaravaglio Alessandro Manello Paolo Nicoli Enrico Gottardi Giuseppe Saglio Daniela Cilloni Marco De Gobbi/titolo:Clinical significance ofTFR2andEPORexpression in bone marrow cells in myelodysplastic syndromes/doi:/rivista:British journal of haematology (Print)/anno:2017/pagina_da:491/pagina_a:495/intervallo_pagine:491–495/volume:176
The experiments were conceived, designed and performed by Augusta Di Savino, Antonietta Palmieri, Marco De Gobbi. RNA extraction from patients' bone marrow samples was performed by Alessandro Volpengo, Francesca Crasto, Roberta Lorenzatti and Enrico
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::1860e89601c18b2a774b96c741048a0b
http://www.cnr.it/prodotto/i/368982
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5
Early BCR-ABL1 Reduction Is Predictive of Better Event-free Survival in Patients With Newly Diagnosed Chronic Myeloid Leukemia Treated With Any Tyrosine Kinase Inhibitor
Autor: Enrico Gottardi, Carmen Fava, Paola Berchialla, Alessandro Volpengo, Filomena Daraio, Irene Dogliotti, Francesca Crasto, Giovanna Rege-Cambrin, Bruno Di Gioacchino, Roberta Lorenzatti, Cristina Fantino, Giuseppe Saglio
Publikováno v: Clinical lymphoma, myelomaleukemia.
An early molecular response has a strong predictive value in chronic myeloid leukemia (CML). Recently, the halving time (velocity of early BCR-ABL1 transcript elimination) has been shown to represent an additional prognostic index. Our objective was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb005c13aec35328c8e83748158d149
https://pubmed.ncbi.nlm.nih.gov/27131622
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9
Consistency Of RQ-PCR Analysis Results In Peripheral Blood and Bone Marrow Samples In Chronic Myeloid Leukemia Patients: Relevance From The Practical and Logistic Point Of View
Autor: Giovanna Rege-Cambrin, Carmen Fava, Enrico Gottardi, Filomena Daraio, Emilia Giugliano, Francesca Crasto, Roberta Lorenzatti, Alessandro Volpengo, Bruno Di Gioacchino, Giuseppe Saglio
Publikováno v: Blood. 122:2592-2592
Background Consensus has been achieved that standardized molecular quantitative analysis (RQ-PCR) on peripheral blood (PB) is a suitable method for monitoring residual disease in chronic myeloid leukemia (CML). However, BM is still obtained at specif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54809d80c5bcc16a23de7e66065160ec
https://doi.org/10.1182/blood.v122.21.2592.2592
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10
A Sensitive Replicate RQ-PCR of BCR ABL Transcripts Suggests That A Large Portion of Long Term Post Allogeneic SCT CML Patients Are in Deep MR and May Therefore Be Cured From Their Disease
Autor: Avichai Shimoni, Maya Koren-Michowitz, Yulia Volchek, Enrico Gottardi, Ninette Amariglio, Francesca Crasto, Giuseppe Saglio, Arnon Nagler, Roberta Lorenzatti, Filomena Daraio
Publikováno v: Blood. 120:1690-1690
Abstract 1690 RQ-PCR has become the major method for the follow up of CML pts in the tyrosine kinase inhibitor (TKI) era. In CML pts undergoing allogeneic SCT (Allo-SCT) it has been shown that successive increase in quantitative BCR ABL transcript le
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd64fc06b0c81faaca83621b61175e68
https://doi.org/10.1182/blood.v120.21.1690.1690
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