Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Francesca Coscia"'
Autor:
Laura Tosatto, Francesca Coscia
Publikováno v:
European Thyroid Journal, Vol 11, Iss 3, Pp 1-11 (2023)
Thyroid hormones are essential for the metabolism of vertebrates and their synthesis, storage and release in the thyroid gland are orchestrated by their large protein precursor thyroglobulin (Tg). Alterations of Tg structure and localisation often co
Externí odkaz:
https://doaj.org/article/1d3bab778af640a78506b4f800172653
Autor:
Elisa Stellaria Grassi, Giuditta Rurale, Tiziana de Filippis, Davide Gentilini, Erika Carbone, Francesca Coscia, Sarah Uraghi, Martyn Bullock, Roderick J. Clifton-Bligh, Abhinav K. Gupta, Luca Persani
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionFOXE1 is required for thyroid function and its homozygous mutations cause a rare syndromic form of congenital hypothyroidism (CH). FOXE1 has a polymorphic polyalanine tract whose involvement in thyroid pathology is controversial. Starting
Externí odkaz:
https://doaj.org/article/09451781c69c48e488588594e6a31c4c
Autor:
Alessia Mauri, Alessandra Duse, Giacomo Palm, Roberto Previtali, Stefania Maria Bova, Sara Olivotto, Sara Benedetti, Francesca Coscia, Pierangelo Veggiotti, Cristina Cereda
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13560 (2022)
GLUT1 deficiency syndrome (GLUT1DS1; OMIM #606777) is a rare genetic metabolic disease, characterized by infantile-onset epileptic encephalopathy, global developmental delay, progressive microcephaly, and movement disorders (e.g., spasticity and dyst
Externí odkaz:
https://doaj.org/article/ed81d56e8fa94c219634a698252dec89
Autor:
Juan Reguera, Piotr Gerlach, Maria Rosenthal, Stephanie Gaudon, Francesca Coscia, Stephan Günther, Stephen Cusack
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005636 (2016)
Segmented negative strand RNA viruses of the arena-, bunya- and orthomyxovirus families uniquely carry out viral mRNA transcription by the cap-snatching mechanism. This involves cleavage of host mRNAs close to their capped 5' end by an endonuclease (
Externí odkaz:
https://doaj.org/article/c6fc692a9aa444eab62725017444c33d
Autor:
Francesca Coscia, Jan Löwe
Publikováno v:
FEBS Letters. 595:2691-2700
In bacteria, Lon is a large hexameric ATP-dependent protease that targets misfolded and also folded substrates, some of which are involved in cell division and survival of cellular stress. The N-terminal domain of Lon facilitates substrate recognitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2a745acb42198318739a9d4ce19951
https://doi.org/10.1002/1873-3468.14199
https://doi.org/10.1002/1873-3468.14199
Autor:
Cereda, Alessia Mauri, Alessandra Duse, Giacomo Palm, Roberto Previtali, Stefania Maria Bova, Sara Olivotto, Sara Benedetti, Francesca Coscia, Pierangelo Veggiotti, Cristina
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13560
GLUT1 deficiency syndrome (GLUT1DS1; OMIM #606777) is a rare genetic metabolic disease, characterized by infantile-onset epileptic encephalopathy, global developmental delay, progressive microcephaly, and movement disorders (e.g., spasticity and dyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::5d55e7384360cd7c20696ef08e639caa
Autor:
Alessia Mauri, Alessandra Duse, Giacomo Palm, Roberto Previtali, Stefania Maria Bova, Sara Olivotto, Sara Benedetti, Francesca Coscia, Pierangelo Veggiotti, Cristina Cereda
GLUT1 deficiency syndrome (GLUT1DS1; OMIM #606777) is a rare genetic metabolic disease, characterized by infantile-onset epileptic encephalopathy, global developmental delay, progressive microcephaly and movement disorders (e.g. spasticity and dyston
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d31c503ad796d6768346062facccdc
https://doi.org/10.1101/2022.09.26.509448
https://doi.org/10.1101/2022.09.26.509448
Autor:
Laura Tosatto, Francesca Coscia
Publikováno v:
European thyroid journal. 11(3)
Thyroid hormones are essential for the metabolism of vertebrates and their synthesis, storage and release in the thyroid gland are orchestrated by their large protein precursor thyroglobulin (Tg). Alterations of Tg structure and localisation often co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869d3081bb82bea204abb8ee324ac696
https://pubmed.ncbi.nlm.nih.gov/35544053
https://pubmed.ncbi.nlm.nih.gov/35544053
Autor:
Francesca Coscia, Ajda Taler-Verčič
Publikováno v:
Molecular and Cellular Endocrinology
The thyroid gland accumulates the rare dietary element iodine and incorporates it into iodinated thyroid hormones, utilising several tightly regulated reactions and molecular mechanisms. Thyroid hormones are essential in vertebrates and play a centra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafede7565050a078a0126f147b75b62
https://pubmed.ncbi.nlm.nih.gov/33964321
https://pubmed.ncbi.nlm.nih.gov/33964321
Autor:
Long-Fei Wu, Kasim Sader, Pablo Castro-Hartmann, Jan Löwe, Kyle W. Muir, Pu Qian, Dari Kimanius, Francesca Coscia, Kyle Dent, John D. Sutherland, Christopher J. Russo, M. J. Peet, David Barford, Katerina Naydenova, Ziguo Zhang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences
Significance While the current COVID-19 pandemic continues, the US Food and Drug Administration (FDA) has approved only one drug against the virus—remdesivir. It is a nucleotide analogue inhibitor of the SARS-CoV-2 RNA-dependent RNA polymerase; fav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e21905789c96124d65b476169d06d7
https://pubmed.ncbi.nlm.nih.gov/33526596
https://pubmed.ncbi.nlm.nih.gov/33526596