Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Francesca Chappell"'
Autor:
Joanna M Wardlaw, Baljean Dhillon, Fergus Doubal, Samuel Gibbon, Francesca Chappell, Thomas MacGillivray
Publikováno v:
BMJ Neurology Open, Vol 6, Iss 2 (2024)
Objective To test for associations between optic disc pallor and two clinical variables: ischaemic stroke subtype (cortical and lacunar) and cerebral small vessel disease (SVD) scores in a cohort of hospital patients admitted with mild stroke (Mild S
Externí odkaz:
https://doaj.org/article/3b97a3f3b5fa45da97bf0280e2411f9c
Autor:
Grant Mair, Philip White, Philip M. Bath, Keith Muir, Chloe Martin, David Dye, Francesca Chappell, Rüdiger vonKummer, Malcolm Macleod, Nikola Sprigg, Joanna M. Wardlaw, for the RITeS Collaboration
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 7, Pp 1072-1082 (2023)
Abstract Objective Software developed using artificial intelligence may automatically identify arterial occlusion and provide collateral vessel scoring on CT angiography (CTA) performed acutely for ischemic stroke. We aimed to assess the diagnostic a
Externí odkaz:
https://doaj.org/article/0ef113e3813d4edba87369cbfe618482
Autor:
Rui Li, Eric Harshfield, Steven Bell, Michael Burkhart, Anil Tuladhar, Saima Hilal, Daniel Tozer, Francesca Chappell, Stephen Makin, Jessica Lo, Joanna Wardlaw, Frank-Erik de Leeuw, Christopher Chen, Zoe Kourtzi, Hugh Markus
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100235- (2024)
Introduction: Cerebral small vessel disease (SVD) contributes to 45% of dementia cases worldwide. Only a minority of SVD patients develop dementia, yet we lack a reliable model for predicting incident dementia in SVD. Most attempts to date have relie
Externí odkaz:
https://doaj.org/article/258f4cb4ab2146e6af7cf5085e948f47
Autor:
Angela Jochems, Susana Muñoz Maniega, Una Clancy, Daniela Jaime Garcia, Carmen Arteaga, Mariadel C. Valdés Hernández, Will Hewins, Rachel Penman, Ellen Backhouse, Stewart Wiseman, Michael Thrippleton, Michael Stringer, Francesca Chappell, Fergus Doubal, Joanna Wardlaw
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100243- (2024)
Introduction: White matter hyperintensities (WMH) are related to cognitive decline, particularly processing speed and executive functioning (EF). However, all cognitive domains might be affected. WMH can regress and this might have positive consequen
Externí odkaz:
https://doaj.org/article/cdfa1742bc5f4ccab31238ff7e761651
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100254- (2024)
Introduction: The long-term evolution of recent small subcortical infarcts (SSIs) remains insufficiently characterized. Previous studies have indicated haemosiderin deposits (HD) in SSIs during their subacute and chronic stages. Our study aims to pro
Externí odkaz:
https://doaj.org/article/2d63332b97f8432393921570e816692f
Autor:
Michael S. Stringer, Anna K. Heye, Paul A. Armitage, Francesca Chappell, Maria del C. Valdés Hernández, Stephen D.J. Makin, Eleni Sakka, Michael J. Thrippleton, Joanna M. Wardlaw
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102883- (2021)
Subtle blood–brain barrier (BBB) permeability increases have been shown in small vessel disease (SVD) using various analysis methods. Following recent consensus recommendations, we used Patlak tracer kinetic analysis, considered optimal in low perm
Externí odkaz:
https://doaj.org/article/f635bc0137e744758b0076d27a555a86
Autor:
Grant Mair, Chloe Martin, Francesca Chappell, Philip M. Bath, David Dye, Rüdiger von Kummer, Keith W. Muir, Peter A. G. Sandercock, Rustam Al-Shahi Salman, Nikola Sprigg, Malcolm Macleod, Joanna M. Wardlaw, Philip White
Publikováno v:
AMRC Open Research, Vol 2 (2020)
Background: Artificial intelligence-based software may automatically detect ischaemic stroke lesions and provide an Alberta Stroke Program Early CT score (ASPECTS) on CT, and identify arterial occlusion and provide a collateral score on CTA. Large-sc
Externí odkaz:
https://doaj.org/article/1b6aa2002bf44962b52b3337b2a03f5b
Autor:
Joanna Wardlaw, Miriam Brazzelli, Hector Miranda, Francesca Chappell, Paul McNamee, Graham Scotland, Zahid Quayyum, Duncan Martin, Kirsten Shuler, Peter Sandercock, Martin Dennis
Publikováno v:
Health Technology Assessment, Vol 18, Iss 27 (2015)
Externí odkaz:
https://doaj.org/article/dcb46be84ded4d7fa801c3b48ad28d43
Autor:
Joanna Wardlaw, Miriam Brazzelli, Hector Miranda, Francesca Chappell, Paul McNamee, Graham Scotland, Zahid Quayyum, Duncan Martin, Kirsten Shuler, Peter Sandercock, Martin Dennis
Publikováno v:
Health Technology Assessment, Vol 18, Iss 27 (2014)
Background: Patients with transient ischaemic attack (TIA) or minor stroke need rapid treatment of risk factors to prevent recurrent stroke. ABCD2 score or magnetic resonance diffusion-weighted brain imaging (MR DWI) may help assessment and treatment
Externí odkaz:
https://doaj.org/article/8a879dfbdaa749ae88fbe52470f857a4
Autor:
Stefan Sennfält, Michael J Thrippleton, Michael Stringer, Carmen Arteaga Reyes, Francesca Chappell, Fergus Doubal, Daniela J Garcia, Junfang Zhang, Yajun Cheng, Joanna Wardlaw
Publikováno v:
Sennfält, S, Thrippleton, M J, Stringer, M, Reyes, C A, Chappell, F, Doubal, F, Garcia, D J, Zhang, J, Cheng, Y & Wardlaw, J 2023, ' Visualising and semi-quantitatively measuring brain fluid pathways, including meningeal lymphatics, in humans using widely available MRI techniques ', Journal of Cerebral Blood Flow and Metabolism, pp. 0271678X2311795 . https://doi.org/10.1177/0271678X231179555
Brain fluid dynamics remains poorly understood with central issues unresolved. In this study, we first review the literature regarding points of controversy, then pilot study if conventional MRI techniques can assess brain fluid outflow pathways and