Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Francesca Capotosti"'
Autor:
Ruben Smith, Francesca Capotosti, Martin Schain, Tomas Ohlsson, Efthymia Vokali, Jerome Molette, Tanja Touilloux, Valerie Hliva, Ioannis K. Dimitrakopoulos, Andreas Puschmann, Jonas Jögi, Per Svenningsson, Mattias Andréasson, Christine Sandiego, David S. Russell, Patricia Miranda-Azpiazu, Christer Halldin, Erik Stomrud, Sara Hall, Klas Bratteby, Elina Tampio L’Estrade, Ruth Luthi-Carter, Andrea Pfeifer, Marie Kosco-Vilbois, Johannes Streffer, Oskar Hansson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract A positron emission tomography (PET) tracer detecting α-synuclein pathology will improve the diagnosis, and ultimately the treatment of α-synuclein-related diseases. Here we show that the PET ligand, [18F]ACI-12589, displays good in vitro
Externí odkaz:
https://doaj.org/article/8e2d2bdd4dfc4ecea2658cceed5ad9e8
Autor:
Francesca Capotosti, Efthymia Vokali, Jerome Molette, Myriam Ravache, Christophe Delgado, Jacqueline Kocher, Laure Pittet, Coralie Vallet, Andreia Serra, Kasia Piorkowska, Ioannis K Dimitrakopoulos, Ruth Luthi‐Carter, Elpida Tsika, Tanja Touilloux, Valerie Hliva, Ruben Smith, Oskar Hansson, Johannes Streffer, Andrea Pfeifer, Marie Kosco‐Vilbois
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52073098c0a5adf3913a87f5a12e4b01
https://doi.org/10.1002/alz.064680
https://doi.org/10.1002/alz.064680
Autor:
Ruben Smith, Francesca Capotosti, Martin Schain, Tomas Ohlsson, Tanja Touilloux, Valerie Hliva, Efthymia Vokali, Ruth Luthi‐Carter, Jerome Molette, Ioannis K Dimitrakopoulos, Jonas Jögi, Erik Stomrud, Sara Hall, Klas Bratteby, Elina Tampio, Andrea Pfeifer, Marie Kosco‐Vilbois, Johannes Streffer, Oskar Hansson
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d6a9c336487f7b7f5333ddb8924960c
https://doi.org/10.1002/alz.065394
https://doi.org/10.1002/alz.065394
Autor:
Francesca Capotosti, Emanuele Gabellieri, Ludger Dinkelborg, Hanno Schieferstein, Nampally Sreenivasachary, Andre Mueller, Mathias Berndt, Heiko Kroth, Andrew W. Stephens, David T. Hickman, Andreia Monica Serra, Andrea Pfeifer, Heribert Schmitt-Willich, Jérôme Molette, Felix Oden
Publikováno v:
Journal of Medicinal Chemistry. 64:12808-12830
The first candidate PI-2014 was tested in healthy controls and subjects with Alzheimer's disease (AD). As PI-2014 displayed off-target binding to monoamine oxidase A (MAO-A), a new lead with improved binding to Tau and decreased MAO-A binding was req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2e826303fd6fd1e6ecb77723cc30be7
https://doi.org/10.1021/acs.jmedchem.1c00861
https://doi.org/10.1021/acs.jmedchem.1c00861
Autor:
Francesca Capotosti, Efthymia Vokali, Jerome Molette, Myriam Ravache, Christophe Delgado, Jacqueline Kocher, Laure Pittet, Ioannis K. Dimitrakopoulos, Ivan Di‐Bonaventura, Tanja Touilloux, Kasia Piorkowska, Mayank Chauhan, Heiko Kroth, Valerie Hliva, Olivier Sol, Andrea Pfeifer, Marie Kosco‐Vilbois
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1127fce6d100eda3c392cbb5a85e2ff
https://doi.org/10.1002/alz.053943
https://doi.org/10.1002/alz.053943
Autor:
Klas Bratteby, Elina Tampio L’Estrade, Ioannis Dimitrakopoulos, Jerome Molette, Bálint Gabos, Annéa Henriksson, Francesca Capotosti, Oskar Hansson, Ruben Smith, Tomas Ohlsson
Publikováno v:
Nuclear Medicine and Biology. :S87-S88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::665459ffef703f6746101f641f006a0b
https://doi.org/10.1016/s0969-8051(22)00207-4
https://doi.org/10.1016/s0969-8051(22)00207-4
Autor:
Yvan Varisco, Francesca Capotosti, Ludger Dinkelborg, Cédric Boudou, Emanuele Gabellieri, Gilles Tamagnan, David T. Hickman, Vincent Darmency, Andrew W. Stephens, Andre Mueller, Heiko Kroth, Mathias Berndt, Tanja Juergens, Jérôme Molette, Andrea Pfeifer, Heribert Schmitt-Willich, Hanno Schieferstein, Efthymia Vokali, Felix Oden, Andreas Muhs
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 46:2178-2189
Purpose Tau deposition is a key pathological feature of Alzheimer’s disease (AD) and other neurodegenerative disorders. The spreading of tau neurofibrillary tangles across defined brain regions corresponds to the observed level of cognitive decline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c502df1f676d2e3b0868badd00cdf7
https://doi.org/10.1007/s00259-019-04397-2
https://doi.org/10.1007/s00259-019-04397-2
Autor:
Ludger Dinkelborg, Hanno Schieferstein, Tanja Juergens, Andrew W. Stephens, Nampally Sreenivasachary, Felix Oden, Mathias Berndt, Emanuele Gabellieri, Andre Mueller, Heiko Kroth, Jérôme Molette, Yvan Varisco, Andrea Pfeifer, David T. Hickman, Francesca Capotosti, Heribert Schmitt-Willich
Publikováno v:
European journal of medicinal chemistry. 204
The compound screening was initiated with a direct staining assay to identify compounds binding to Tau aggregates and not Abeta plaques using human brain sections derived from late stage Alzheimer's disease donors. The binding of Tau aggregate select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eae20009bd62126268dd92bca1c77a3
https://pubmed.ncbi.nlm.nih.gov/32771872
https://pubmed.ncbi.nlm.nih.gov/32771872
Autor:
Emanuele Gabellieri, Sonia M. Poli, Allan Lamontanara, Andrea Pfeifer, Francesca Capotosti, Yvan Varisco, David Lowe, David T. Hickman, Kasia Piorkowska, Heiko Kroth, Sreenivasachary Nampally, Patrick Rodriguez
Publikováno v:
Alzheimer's & Dementia. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba744bf2f31e5cefa480e8983889c44d
https://doi.org/10.1016/j.jalz.2019.06.4866
https://doi.org/10.1016/j.jalz.2019.06.4866
Autor:
Heiko, Kroth, Felix, Oden, Jerome, Molette, Hanno, Schieferstein, Francesca, Capotosti, Andre, Mueller, Mathias, Berndt, Heribert, Schmitt-Willich, Vincent, Darmency, Emanuele, Gabellieri, Cédric, Boudou, Tanja, Juergens, Yvan, Varisco, Efthymia, Vokali, David T, Hickman, Gilles, Tamagnan, Andrea, Pfeifer, Ludger, Dinkelborg, Andreas, Muhs, Andrew, Stephens
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose Tau deposition is a key pathological feature of Alzheimer’s disease (AD) and other neurodegenerative disorders. The spreading of tau neurofibrillary tangles across defined brain regions corresponds to the observed level of cognitive decline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e37d71c63a7bb9e0f5c438e1b89bedf
https://pubmed.ncbi.nlm.nih.gov/31264169
https://pubmed.ncbi.nlm.nih.gov/31264169