Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Francesca Belardinilli"'
Autor:
Cristina Capuano, Davide De Federicis, Daniel Ciuti, Ombretta Turriziani, Antonio Angeloni, Emanuela Anastasi, Giuseppe Giannini, Francesca Belardinilli, Rosa Molfetta, Domenico Alvaro, Gabriella Palmieri, Ricciarda Galandrini
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNatural Killer (NK) cells contribute to the protective effects of vaccine-induced antibodies thanks to the low affinity receptor for IgG, FcγRIIIA/CD16, whose aggregation leads to the killing of infected cells and IFNγ release, through
Externí odkaz:
https://doaj.org/article/20f1dcb71bed4255999f62380e3fdef7
Autor:
Chiara Nicolazzo, Valentina Magri, Luca Marino, Francesca Belardinilli, Federica Di Nicolantonio, Gianluigi De Renzi, Salvatore Caponnetto, Michela De Meo, Giuseppe Giannini, Daniele Santini, Enrico Cortesi, Paola Gazzaniga
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe term “neo-RAS wild-type” refers to the switch to RAS wild-type disease in plasma circulating tumor DNA (ctDNA) from originally RAS mutant colorectal cancers. Consistently, the hypothesis to re-determine RAS mutational status in ctDN
Externí odkaz:
https://doaj.org/article/f31220dbcbd84026adf56cdad21c1383
Publikováno v:
Biology Direct, Vol 17, Iss 1, Pp 1-16 (2022)
Abstract Background Historically, the molecular classification of colorectal cancer (CRC) was based on the global genomic status, which identified microsatellite instability in mismatch repair (MMR) deficient CRC, and chromosomal instability in MMR p
Externí odkaz:
https://doaj.org/article/2253b9391be14a909391672b2fd190ca
Autor:
Arianna Nicolussi, Francesca Belardinilli, Laura Ottini, Marialaura Petroni, Carlo Capalbo, Giuseppe Giannini, Anna Coppa
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 12, Pp n/a-n/a (2020)
Abstract Background BRCA1/2 VUSs represent an important clinical issue in risk assessment for the breast/ovarian cancer families (HBOC) families. Among them, some occurring within the intron‐exon boundary may lead to aberrant splicing process by al
Externí odkaz:
https://doaj.org/article/e4ea74c0396e45ec882710d7a06ef8db
Autor:
Francesca Belardinilli, Carlo Capalbo, Umberto Malapelle, Pasquale Pisapia, Domenico Raimondo, Edoardo Milanetti, Mahdavian Yasaman, Carlotta Liccardi, Paola Paci, Pasquale Sibilio, Francesco Pepe, Caterina Bonfiglio, Silvia Mezi, Valentina Magri, Anna Coppa, Arianna Nicolussi, Angela Gradilone, Marialaura Petroni, Stefano Di Giulio, Francesca Fabretti, Paola Infante, Sonia Coni, Gianluca Canettieri, Giancarlo Troncone, Giuseppe Giannini
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Extensive molecular characterization of human colorectal cancer (CRC) via Next Generation Sequencing (NGS) indicated that genetic or epigenetic dysregulation of a relevant, but limited, number of molecular pathways typically occurs in this tumor. The
Externí odkaz:
https://doaj.org/article/0b3984ae08894e55827693487456c527
Autor:
Chiara Nicolazzo, Francesca Belardinilli, Salvatore Caponnetto, Angela Gradilone, Enrico Cortesi, Giuseppe Giannini, Paola Gazzaniga
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Externí odkaz:
https://doaj.org/article/fa6a122ffdbb4e5288ec66ede710eb1c
Autor:
Chiara Nicolazzo, Alain Gelibter, Irene Bottillo, Francesca Belardinilli, Simona Pisegna, Gianluigi De Renzi, Daniele Marinelli, Paola Grammatico, Enrico Cortesi, Giuseppe Giannini, Paola Gazzaniga
Publikováno v:
Diagnostics, Vol 11, Iss 12, p 2196 (2021)
Although molecular profiling at diagnosis has traditionally relied on direct sampling of neoplastic tissue, cancer clonal evolution represents a critical obstacle to use primary tissue biopsies to guide clinical decision-making at the time of progres
Externí odkaz:
https://doaj.org/article/bd2a1c2dc5bb48b29f154ecfb554a37b
Autor:
Arianna Nicolussi, Francesca Belardinilli, Valentina Silvestri, Yasaman Mahdavian, Virginia Valentini, Sonia D’Inzeo, Marialaura Petroni, Massimo Zani, Sergio Ferraro, Stefano Di Giulio, Francesca Fabretti, Beatrice Fratini, Angela Gradilone, Laura Ottini, Giuseppe Giannini, Anna Coppa, Carlo Capalbo
Publikováno v:
PeerJ, Vol 7, p e7972 (2019)
Background Genetic testing for BRCA1/2 germline mutations in hereditary breast/ovarian cancer patients requires screening for single nucleotide variants, small insertions/deletions and large genomic rearrangements (LGRs). These studies have long been
Externí odkaz:
https://doaj.org/article/85e327b29acf4025bee0ed5b00f74e12
Autor:
Arianna Nicolussi, Francesca Belardinilli, Yasaman Mahdavian, Valeria Colicchia, Sonia D’Inzeo, Marialaura Petroni, Massimo Zani, Sergio Ferraro, Virginia Valentini, Laura Ottini, Giuseppe Giannini, Carlo Capalbo, Anna Coppa
Publikováno v:
PeerJ, Vol 7, p e6661 (2019)
Background Conventional methods used to identify BRCA1 and BRCA2 germline mutations in hereditary cancers, such as Sanger sequencing/multiplex ligation-dependent probe amplification (MLPA), are time-consuming and expensive, due to the large size of t
Externí odkaz:
https://doaj.org/article/af709bd668db45ada5e1a66a6ebf63d9
Autor:
Cristina Capuano, Chiara Pighi, Rosa Molfetta, Rossella Paolini, Simone Battella, Gabriella Palmieri, Giuseppe Giannini, Francesca Belardinilli, Angela Santoni, Ricciarda Galandrini
Publikováno v:
OncoImmunology, Vol 6, Iss 3 (2017)
Natural killer (NK) cell-mediated antibody-dependent cellular cytotoxicity (ADCC), based on the recognition of IgG-opsonized targets by the low-affinity receptor for IgG FcγRIIIA/CD16, represents one of the main mechanisms by which therapeutic antib
Externí odkaz:
https://doaj.org/article/950382343a73492ebab87a649bae495a