Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Francesca Anson"'
Exogenous Introduction of Initiator and Executioner Caspases Results in Different Apoptotic Outcomes
Publikováno v:
JACS Au, Vol 1, Iss 8, Pp 1240-1256 (2021)
Externí odkaz:
https://doaj.org/article/72d8e511927844128801c27706b55122
Exogenous Introduction of Initiator and Executioner Caspases Results in Different Apoptotic Outcomes
Publikováno v:
JACS Au, Vol 1, Iss 8, Pp 1240-1256 (2021)
JACS Au
JACS Au
The balance of pro-apoptotic and pro-survival proteins defines a cell's fate. These processes are controlled through an interdependent and finely tuned protein network that enables survival or leads to apoptotic cell death. The caspase family of prot
Publikováno v:
Angewandte Chemie. 134
Autor:
Poornima Rangadurai, Alam García-Heredia, Thameez M. Koyasseril-Yehiya, Sankaran Thayumanavan, M. Sloan Siegrist, Francesca Anson
Publikováno v:
Nanoscale. 12:20693-20698
The propensity of broad-spectrum antibiotics to indiscriminately kill both pathogenic and beneficial bacteria has a profound impact on the spread of resistance across multiple bacterial species. Alternative approaches that narrow antibacterial specif
Publikováno v:
Biomacromolecules
The ability for biologics to access intracellular targets hinges on the translocation of active, unmodified proteins. This is often achieved using nanoscale formulations, which enter cells through endocytosis. This uptake mechanism often limits the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2650c2d2c86b569c8d27494e380ccf5f
https://europepmc.org/articles/PMC8477791/
https://europepmc.org/articles/PMC8477791/
Publikováno v:
Protein Sci
Cytosolic protein delivery promises diverse applications from therapeutics, to genetic modification and precision research tools. To achieve effective cellular and subcellular delivery, approaches that allow protein visualization and accurate localiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f32f0326bbd012d058ae7bca4424824
https://europepmc.org/articles/PMC7784757/
https://europepmc.org/articles/PMC7784757/
Autor:
Thameez M, Koyasseril-Yehiya, Alam, García-Heredia, Francesca, Anson, Poornima, Rangadurai, M Sloan, Siegrist, S, Thayumanavan
Publikováno v:
Nanoscale
The propensity of broad-spectrum antibiotics to indiscriminately kill both pathogenic and beneficial bacteria has a profound impact on the spread of resistance across multiple bacterial species. Alternative approaches that narrow antibacterial specif
Autor:
Sankaran Thayumanavan, Bin Liu, Shuai Gong, Mine Canakci, Myrat Kurbanov, Wardah Ejaz, Francesca Anson
Publikováno v:
Nano Lett
Intracellular delivery of functional proteins is a promising, but challenging, strategy for many therapeutic applications. Here, we report a new methodology that overcomes drawbacks of traditional mesoporous silica (MSi) particles for protein deliver
Publikováno v:
Journal of the American Chemical Society. 141(45)
Interfacial chemistry provides an opportunity to control dynamic materials. By harnessing the dynamic covalent nature of imine bonds, emulsions are generated in situ, predictably manipulated, and ultimately destroyed along liquid-liquid and emulsion-
Autor:
Mine Canakci, Mallory R Gordon, Francesca Anson, Bo Zhao, Celia C. Homyak, Richard W. Vachet, Ann Fernandez, Sankaran Thayumanavan, Khushboo Singh
Here, we have exploited the heightened extracellular concentration of matrix metalloproteinase-9 (MMP-9) to induce surface-conversional properties of nanogels with the aim of tumor-specific enhanced cellular uptake. A modular polymeric nanogel platfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30762950236c0f3511aae25fb3ec10c1
https://europepmc.org/articles/PMC6298948/
https://europepmc.org/articles/PMC6298948/