Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Francesca, Logiacco"'
Autor:
Francesca Logiacco, Laura Cathleen Grzegorzek, Elizabeth C. Cordell, Oliver Popp, Philipp Mertins, David H. Gutmann, Helmut Kettenmann, Marcus Semtner
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract We previously discovered a sex-by-genotype defect in microglia function using a heterozygous germline knockout mouse model of Neurofibromatosis type 1 (Nf1 ± mice), in which only microglia from male Nf1 ± mice exhibited defects in purinerg
Externí odkaz:
https://doaj.org/article/9d5a9756881946f5958a17392cf3aabf
Autor:
Dilansu Guneykaya, Bilge Ugursu, Francesca Logiacco, Oliver Popp, Maria Almut Feiks, Niklas Meyer, Stefan Wendt, Marcus Semtner, Fatma Cherif, Christian Gauthier, Charlotte Madore, Zhuoran Yin, Özcan Çınar, Taner Arslan, Zoltan Gerevich, Philipp Mertins, Oleg Butovsky, Helmut Kettenmann, Susanne A. Wolf
Publikováno v:
Brain, Behavior, and Immunity. 111:61-75
Neuroligin-4 (NLGN4) loss-of-function mutations are associated with monogenic heritable autism spectrum disorder (ASD) and cause alterations in both synaptic and behavioral phenotypes. Microglia, the resident CNS macrophages, are implicated in ASD de
Autor:
Nirmeen Elmadany, Francesca Logiacco, Alice Buonfiglioli, Verena C. Haage, Elizabeth C. Wright-Jin, Alexander Schattenberg, Roxane M. Papawassiliou, Helmut Kettenmann, Marcus Semtner, David H. Gutmann
Publikováno v:
Neurobiology of Disease, Vol 144, Iss , Pp 105030- (2020)
As critical regulators of brain homeostasis, microglia are influenced by numerous factors, including sex and genetic mutations. To study the impact of these factors on microglia biology, we employed genetically engineered mice that model Neurofibroma
Externí odkaz:
https://doaj.org/article/9e0770fe1b7e43c2bbca4f9a3728af3b
Publikováno v:
GliaREFERENCES. 69(9)
Histamine is a monoaminergic neurotransmitter which is released within the entire brain from ascending axons originating in the tuberomammillary nucleus in a sleep state-dependent fashion. Besides the modulation of neuronal firing patterns, brain his
Autor:
Francesca, Logiacco, Pengfei, Xia, Svilen Veselinov, Georgiev, Celeste, Franconi, Yi-Jen, Chang, Bilge, Ugursu, Anje, Sporbert, Ralf, Kühn, Helmut, Kettenmann, Marcus, Semtner
Publikováno v:
Cell reports. 37(13)
Microglia, the resident macrophages in the central nervous system, express receptors for classical neurotransmitters, such as γ-aminobutyric acid (GABA) and glutamate, suggesting that they sense synaptic activity. To detect microglial Ca
Autor:
Verena Haage, Stefan Wendt, Helmut Kettenmann, Nirmeen Elmadany, Josien Visser, Philipp Mertins, Dolores Hambardzumyan, Daniel Hernández, Marcus Semtner, Francesca Logiacco, Felipe de Almeida Sassi, Susanne A. Wolf
Publikováno v:
J Neurosci
Microglial cells are considered as sensors of brain pathology by detecting any sign of brain lesions, infections, or dysfunction and can influence the onset and progression of neurological diseases. They are capable of sensing their neuronal environm