Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Francesca, Duraturo"'
Autor:
Mimmo Turano, Rosario Vicidomini, Francesca Cammarota, Valeria D’Agostino, Francesca Duraturo, Paola Izzo, Marina De Rosa
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1428 (2023)
Colorectal cancer (CRC) stands as the third most significant contributor to cancer-related mortality worldwide. A major underlying reason is that the detection of CRC usually occurs at an advanced metastatic stage, rendering therapies ineffective. In
Externí odkaz:
https://doaj.org/article/393cbc8f06484e9c96f41a50059ff7a3
Publikováno v:
Membranes, Vol 11, Iss 5, p 312 (2021)
Colorectal cancer (CRC) is the third most frequent cancer worldwide and the second greatest cause of cancer deaths. About 75% of all CRCs are sporadic cancers and arise following somatic mutations, while about 10% are hereditary cancers caused by ger
Externí odkaz:
https://doaj.org/article/0f36392c52ae46cba6df9d2562badb8b
Autor:
Raffaella Liccardo, Antonio Nolano, Matilde Lambiase, Carlo Della Ragione, Marina De Rosa, Paola Izzo, Francesca Duraturo
Publikováno v:
Biomedicines, Vol 8, Iss 6, p 167 (2020)
Background: The loss or low expression of DNA mismatch repair (MMR) genes can result in genomic instability and tumorigenesis. One such gene, MSH2, is mutated or rearranged in Lynch syndrome (LS), which is characterized by a high risk of tumor develo
Externí odkaz:
https://doaj.org/article/8e3539812d24414682a2470e060731cf
Publikováno v:
Clinical Medicine Insights: Case Reports, Vol 11 (2018)
Lynch syndrome is an autosomal dominant syndrome that can be subdivided into Lynch syndrome I, or site-specific colonic cancer, and Lynch syndrome II, or extracolonic cancers, particularly carcinomas of the stomach, endometrium, biliary and pancreati
Externí odkaz:
https://doaj.org/article/efcea0f099284458a941acaae7f844a4
Publikováno v:
Gastroenterology Research and Practice, Vol 2017 (2017)
About 10% of total colorectal cancers are associated with known Mendelian inheritance, as Familial Adenomatous Polyposis (FAP) and Lynch syndrome (LS). In these cancer types the clinical manifestations of disease are due to mutations in high-risk all
Externí odkaz:
https://doaj.org/article/1e6abf17255b4662b3dd22caf9d7be3c
Autor:
Marina De Rosa, Daniela Rega, Valeria Costabile, Francesca Duraturo, Antonello Niglio, Paola Izzo, Ugo Pace, Paolo Delrio
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 9 (2016)
Colorectal cancer has been ranked the third and second most prevalent of all cancers in men and women, respectively, and it represents the fourth most common cause of cancer deaths. In 2012, there were 1.4 million estimated cases of colorectal cancer
Externí odkaz:
https://doaj.org/article/755ef578706c4a1f9ec7734c7c254c98
Autor:
Antonio Nolano, Giovanni Battista Rossi, Valentina D’Angelo, Raffaella Liccardo, Marina De Rosa, Paola Izzo, Francesca Duraturo
Publikováno v:
International Journal of Molecular Sciences. 24:5970
Lynch syndrome (LS) is an autosomal dominant inherited disorder that primarily predisposes individuals to colorectal and endometrial cancer. It is associated with pathogenic variants in DNA mismatch repair (MMR) genes. In this study, we report the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e994ec1ca18fe9b8d69b1fe62589a013
https://doi.org/10.3390/ijms24065970
https://doi.org/10.3390/ijms24065970
Autor:
Raffaella Liccardo, Matilde Lambiase, Antonio Nolano, Marina De Rosa, Paola Izzo, Francesca Duraturo
Publikováno v:
International journal of molecular medicine. 49(6)
The molecular characterization of patients with Lynch syndrome (LS) involves germline testing to detect a deleterious mutation in one of the genes of the mismatch repair (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19c3bd4cdbcd9c734eecfe36bcfdf12
https://pubmed.ncbi.nlm.nih.gov/35475445
https://pubmed.ncbi.nlm.nih.gov/35475445
Autor:
Antonio Nolano, Alessia Medugno, Silvia Trombetti, Raffaella Liccardo, Marina De Rosa, Paola Izzo, Francesca Duraturo
Publikováno v:
Cancers. 15:75
Hereditary non-polyposis colorectal cancer is also known as Lynch syndrome. Lynch syndrome is associated with pathogenetic variants in one of the mismatch repair (MMR) genes. In addition to colorectal cancer, the inefficiency of the MMR system leads
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98fa8441b5d1a8c02a20b570009a702
https://doi.org/10.3390/cancers15010075
https://doi.org/10.3390/cancers15010075
Autor:
Raffaella, Liccardo, Raffaele, Sessa, Silvia, Trombetti, Marina, De Rosa, Paola, Izzo, Michela, Grosso, Francesca, Duraturo
Publikováno v:
Cancers
Simple Summary In a previous study, we identified a patient carrying the variant c.*226A>G in the MSH2 3′ untranslated region that showed overexpression of MSH2 protein. In this study, we hypothesized that the MSH2 3′UTR contained a seed region f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe20a4cacfe51b97bb139cd92dbd644f
https://pubmed.ncbi.nlm.nih.gov/34572889
https://pubmed.ncbi.nlm.nih.gov/34572889