Mer Tyrosine Kinase (MERTK) modulates liver fibrosis progression and hepatocellular carcinoma development

Autor: Rosaria Maria Pipitone, Vincenza Calvaruso, Lorenza Di Marco, Francesca Di Salvo, Miriam Gaggianesi, Giulia Lupo, Rossella Zito, Claudia La Mantia, Matteo Ramazzotti, Salvatore Petta, Vito Di Marco, Antonio Craxì, Stefania Grimaudo

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

BackgroundMerTK is a tyrosine kinase receptor that belongs to the TAM (Tyro3/Axl/Mer) receptor family. It is involved in different processes including cellular proliferation/survival, cellular adhesion/migration, and release of the inflammatory/anti-

Externí odkaz: https://doaj.org/article/70ad1692be2c46039a8531c1cf68be7f

Curcumin and Andrographolide Co-Administration Safely Prevent Steatosis Induction and ROS Production in HepG2 Cell Line

Autor: Rosaria Maria Pipitone, Rossella Zito, Giulia Lupo, Ayesha Javed, Claudia La Mantia, Gabriele Di Maria, Giovanni Pratelli, Francesca Di Salvo, Simona Fontana, Marzia Pucci, Daniela Carlisi, Stefania Grimaudo

Publikováno v: Molecules, Vol 28, Iss 3, p 1261 (2023)

Non-alcoholic fatty liver disease (NAFLD) is an emerging chronic liver disease worldwide. Curcumin and andrographolide are famous for improving hepatic functions, being able to reverse oxidative stress and release pro-inflammatory cytokines, and they

Externí odkaz: https://doaj.org/article/ea08eade784649d4864f5e4a0a35dbf8

A cholestatic pattern predicts major liver-related outcomes in patients with non-alcoholic fatty liver disease

Autor: Grazia Pennisi, Rosaria Maria Pipitone, Daniela Cabibi, Marco Enea, Manuel Romero‐Gomez, Mauro Viganò, Elisabetta Bugianesi, Vincent Wai‐Sun Wong, Anna Ludovica Fracanzani, Giada Sebastiani, Annalisa Berzigotti, Francesca Di Salvo, Antonino Giulio Giannone, Claudia La Mantia, Giulia Lupo, Rossana Porcasi, Federica Vernuccio, Rossella Zito, Vito Di Marco, Calogero Cammà, Antonio Craxì, Victor de Ledinghen, Stefania Grimaudo, Salvatore Petta

Publikováno v: Pennisi, Grazia; Pipitone, Rosaria Maria; Cabibi, Daniela; Enea, Marco; Romero-Gomez, Manuel; Viganò, Mauro; Bugianesi, Elisabetta; Wong, Vincent Wai-Sun; Fracanzani, Anna Ludovica; Sebastiani, Giada; Berzigotti, Annalisa; Di Salvo, Francesca; Giannone, Antonino Giulio; La Mantia, Claudia; Lupo, Giulia; Porcasi, Rossana; Vernuccio, Federica; Zito, Rossella; Di Marco, Vito; Cammà, Calogero; ... (2022). A cholestatic pattern predicts major liver-related outcomes in patients with nonalcoholic fatty liver disease. Liver international, 42(5), pp. 1037-1048. Wiley 10.1111/liv.15232

NAFLD patients usually have an increase in AST/ALT levels, but cholestasis can also be observed. We aimed to assess in subjects with NAFLD the impact of the (cholestatic) C pattern on the likelihood of developing major liver-related outcomes (MALO).<

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58435e9199a22d591a7a66f6b3421e6
https://api.elsevier.com/content/abstract/scopus_id/85126031397

Implications of Perineural Invasion on Disease Recurrence and Survival After Pancreatectomy for Pancreatic Head Ductal Adenocarcinoma

Autor: Jun Yu, Jin He, Cristina R. Ferrone, Ilaria Pergolini, Massimo Falconi, Carlos Fernandez-del Castillo, Ammar A. Javed, Matthew J. Weiss, Giuseppe Zamboni, Kim C. Honselmann, Corrado Rubini, Giulia Gasparini, Richard A. Burkhart, G. Belfiori, Stefano Crippa, Francesca Di Salvo, Motaz Qadan, Keith D. Lillemoe, Christopher L. Wolfgang

To describe PNI and to evaluate its impact on disease-free (DFS) and overall survival (OS) in patients with resected pancreatic ductal adenocarcinoma (PDAC).Although PNI is a prognostic factor for survival in many GI cancers, there is limited knowled

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507c6557cdb9fcfe1deb866199ae88c6
http://hdl.handle.net/11562/1028039

Portal vein resection during pancreaticoduodenectomy for pancreatic neuroendocrine tumors. An international multicenter comparative study

Autor: Giuseppe Fusai, Niccolò Napoli, O.R.C. Busch, Claudio Bassi, Sun Whe Kim, Wooil Kwon, Nassiba Beghdadi, Magnus Kjellman, Marco Del Chiaro, Peter Pipan, Jin He, Domenico Tamburrino, Stefano Partelli, T. Armstrong, Francesca Di Salvo, Alain Sauvanet, Mohamed Abu Hilal, Ugo Boggi, Luca Landoni, Christofer L. Wolfgang, Chiara Nessi, Dominik Wiese, Mahmoud Abuawwad, Detlef K. Bartsch, Jin-Young Jang, Safi Dokmak, Panagis M. Lykoudis, E.J.M. Nieveen van Dijkum, Chiara Scandavini, M.G. Besselink, Ammar A. Javed, Peter J. Allen, Massimo Falconi

Publikováno v: Surgery (United States), 169(5), 1093-1101. Mosby Inc.
Fusai, G K, Tamburrino, D, Partelli, S, Lykoudis, P, Pipan, P, di Salvo, F, Beghdadi, N, Dokmak, S, Wiese, D, Landoni, L, Nessi, C, Busch, O R C, Napoli, N, Jang, J-Y, Kwon, W, del Chiaro, M, Scandavini, C, Abu-Awwad, M, Armstrong, T, Hilal, M A, Allen, P J, Javed, A, Kjellman, M, Sauvanet, A, Bartsch, D K, Bassi, C, van Dijkum, E J M N, Besselink, M G, Boggi, U, Kim, S-W, He, J, Wolfgang, C L & Falconi, M 2021, ' Portal vein resection during pancreaticoduodenectomy for pancreatic neuroendocrine tumors. An international multicenter comparative study ', Surgery (United States), vol. 169, no. 5, pp. 1093-1101 . https://doi.org/10.1016/j.surg.2020.11.015

Background: The role of portal vein resection for pancreatic cancer is well established but not for pancreatic neuroendocrine neoplasms. Evidence from studies providing information on long-term outcome after venous resection in pancreatic neuroendocr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcdea2b243fb5ea317d6a31fa857e886
https://pure.amc.nl/en/publications/portal-vein-resection-during-pancreaticoduodenectomy-for-pancreatic-neuroendocrine-tumors-an-international-multicenter-comparative-study(b5ecaa02-451f-4556-ae1f-22f44e6254c2).html