Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Francesc Xavier Avilés"'
Autor:
Isel Pascual Alonso, Fabiola Almeida García, Mario Ernesto Valdés Tresanco, Yarini Arrebola Sánchez, Daniel Ojeda del Sol, Belinda Sánchez Ramírez, Isabelle Florent, Marjorie Schmitt, Francesc Xavier Avilés
Publikováno v:
Marine Drugs, Vol 21, Iss 5, p 279 (2023)
Proteolytic enzymes, also known as peptidases, are critical in all living organisms. Peptidases control the cleavage, activation, turnover, and synthesis of proteins and regulate many biochemical and physiological processes. They are also involved in
Externí odkaz:
https://doaj.org/article/102d50485a2e49cd91774ccf24f6f3e5
Autor:
Aymara Cabrera-Muñoz, Yusvel Sierra-Gómez, Giovanni Covaleda-Cortés, Mey L. Reytor, Yamile González-González, José M. Bautista, Francesc Xavier Avilés, Maday Alonso-del-Rivero
Publikováno v:
Marine Drugs, Vol 21, Iss 2, p 94 (2023)
Metallocarboxypeptidases are zinc-dependent peptide-hydrolysing enzymes involved in several important physiological and pathological processes. They have been a target of growing interest in the search for natural or synthetic compound binders with b
Externí odkaz:
https://doaj.org/article/1711ed6bc716491d8c9ed618244e4455
Autor:
Sergi Rodriguez-Calado, Petra Van Damme, Francesc Xavier Avilés, Ana Paula Candiota, Sebastian Tanco, Julia Lorenzo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1273 (2023)
The cytosolic carboxypeptidase 6 (CCP6) catalyzes the deglutamylation of polyglutamate side chains, a post-translational modification that affects proteins such as tubulins or nucleosome assembly proteins. CCP6 is involved in several cell processes,
Externí odkaz:
https://doaj.org/article/30c6e0dd83a8425d921cd480feaae21d
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2138 (2022)
The yields of soluble ECM proteins recombinantly produced with mammalian cells can be significantly enhanced by exploiting the stabilizing properties of heparin. Here, we propose a simple and straightforward scalable protocol for the mammalian cell p
Externí odkaz:
https://doaj.org/article/877e0d250a7146a5b7a404ccca3a261b
Autor:
Carla Meler-Claramonte, Francesc Xavier Avilés-Jurado, Isabel Vilaseca, Ximena Terra, Paloma Bragado, Gemma Fuster, Xavier León Vintró, Mercedes Camacho
Publikováno v:
Cancers, Vol 14, Iss 9, p 2259 (2022)
The expression of the semaphorin-3F (SEMA3F) and neuropilin-2 (NRP2) is involved in the regulation of lymphangiogenesis. The present study analyzes the relationship between the transcriptional expression of the SEMA3F-NRP2 genes and the presence of o
Externí odkaz:
https://doaj.org/article/cab473c68ee14e7d953e64b896322776
Autor:
Ximena Terra, Victoria Ceperuelo-Mallafré, Carla Merma, Ester Benaiges, Ramon Bosch, Paola Castillo, Joan Carles Flores, Xavier León, Izaskun Valduvieco, Neus Basté, Marina Cámara, Marylène Lejeune, Josep Gumà, Joan Vendrell, Isabel Vilaseca, Sonia Fernández-Veledo, Francesc Xavier Avilés-Jurado
Publikováno v:
Cancers, Vol 13, Iss 7, p 1653 (2021)
Head and neck squamous cell carcinoma (HNSCC) is characterized by high rates of mortality and treatment-related morbidity, underscoring the urgent need for innovative and safe treatment strategies and diagnosis practices. Mitochondrial dysfunction is
Externí odkaz:
https://doaj.org/article/a96f58d0901f4da6b8fd340c869b1aac
Autor:
Javier Garcia-Pardo, Sebastian Tanco, Maria C. Garcia-Guerrero, Sayani Dasgupta, Francesc Xavier Avilés, Julia Lorenzo, Lloyd D. Fricker
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8687 (2020)
Metallocarboxypeptidase Z (CPZ) is a secreted enzyme that is distinguished from all other members of the M14 metallocarboxypeptidase family by the presence of an N-terminal cysteine-rich Frizzled-like (Fz) domain that binds Wnt proteins. Here, we pre
Externí odkaz:
https://doaj.org/article/c221af52bb1f4c62aa74e8a17b9b3f6c
Autor:
Giovanni Covaleda-Cortés, Martha Hernández, Sebastián Alejandro Trejo, Manuel Mansur, Sergi Rodríguez-Calado, Javier García-Pardo, Julia Lorenzo, Josep Vendrell, María Ángeles Chávez, Maday Alonso-del-Rivero, Francesc Xavier Avilés
Publikováno v:
Marine Drugs, Vol 17, Iss 9, p 511 (2019)
A very powerful proteinaceous inhibitor of metallocarboxypeptidases has been isolated from the marine snail Nerita versicolor and characterized in depth. The most abundant of four, very similar isoforms, NvCla, was taken as reference and N-terminally
Externí odkaz:
https://doaj.org/article/5c2b051029aa4aa08814276d42d174c5
Autor:
Juliana Cotabarren, Mariana Edith Tellechea, Sebastián Martín Tanco, Julia Lorenzo, Javier Garcia-Pardo, Francesc Xavier Avilés, Walter David Obregón
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 678 (2018)
Cystine-knot miniproteins (CKMPs) are an intriguing group of cysteine-rich molecules that combine the characteristics of proteins and peptides. Typically, CKMPs are fewer than 50 residues in length and share a characteristic knotted scaffold characte
Externí odkaz:
https://doaj.org/article/4687b878405c4f22a7cfce51d72acaf0
Autor:
Emir Salas-Sarduy, Yasel Guerra, Giovanni Covaleda Cortés, Francesc Xavier Avilés, María A. Chávez Planes
Publikováno v:
Marine Drugs, Vol 15, Iss 4, p 123 (2017)
Natural products from marine origin constitute a very promising and underexplored source of interesting compounds for modern biotechnological and pharmaceutical industries. However, their evaluation is quite challenging and requires specifically desi
Externí odkaz:
https://doaj.org/article/e6c726e7ff6a4b0792db23896f4c61f6