Zobrazeno 1 - 10
of 356
pro vyhledávání: '"Francesc VILLARROYA"'
Autor:
Mona Peyman, Anna Babin-Ebell, Rosalía Rodríguez-Rodríguez, Matilde Rigon, David Aguilar-Recarte, Joan Villarroya, Anna Planavila, Francesc Villarroya, Xavier Palomer, Emma Barroso, Manuel Vázquez-Carrera
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Endoplasmic reticulum (ER) stress-mediated increases in the hepatic levels of the very low-density lipoprotein (VLDL) receptor (VLDLR) promote hepatic steatosis by increasing the delivery of triglyceride-rich lipoproteins to the l
Externí odkaz:
https://doaj.org/article/aa50fcc0fdab48139a2c97688557bd98
Autor:
Cristina Garcia-Beltran, Marion Peyrou, Artur Navarro-Gascon, Abel López-Bermejo, Francis de Zegher, Francesc Villarroya, Lourdes Ibáñez
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionPolycystic ovary syndrome (PCOS) is often associated with metabolic-associated fatty liver disease (MAFLD). MAFLD has been associated with altered hepatic function, systemic dysmetabolism, and abnormal circulating levels of signaling mole
Externí odkaz:
https://doaj.org/article/4c895d1ffc464689914490efdd1d86d1
Autor:
Marta Díaz, Paula Casano, Tania Quesada, Abel López-Bermejo, Francis de Zegher, Francesc Villarroya, Lourdes Ibáñez
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
PurposeExosomes play a key role in cell-to-cell communication by transferring their cargo to target tissues. Little is known on the course of exosome size and number in infants and children.MethodsLongitudinally, we assessed the size and number of ci
Externí odkaz:
https://doaj.org/article/8c7397b6d1f741bc95d06206f922e241
Autor:
Mélanie Escudero, Laurence Vaysse, Gozde Eke, Marion Peyrou, Francesc Villarroya, Sophie Bonnel, Yannick Jeanson, Louisa Boyer, Christophe Vieu, Benoit Chaput, Xi Yao, Frédéric Deschaseaux, Mélissa Parny, Isabelle Raymond‐Letron, Christian Dani, Audrey Carrière, Laurent Malaquin, Louis Casteilla
Publikováno v:
Advanced Science, Vol 10, Iss 31, Pp n/a-n/a (2023)
Abstract Obesity and type 2 diabetes are becoming a global sociobiomedical burden. Beige adipocytes are emerging as key inducible actors and putative relevant therapeutic targets for improving metabolic health. However, in vitro models of human beige
Externí odkaz:
https://doaj.org/article/83470d91099c4eaf88a947e0c14bbee6
Autor:
Pere Domingo, Marta Giralt, Aleix Gavaldà-Navarro, Albert Blasco-Roset, Alejandro Delgado-Anglés, José Miguel Gallego-Escuredo, Maria Del Mar Gutiérrez, Maria Gracia Mateo, Rubén Cereijo, Joan Carles Domingo, Francesc Villarroya, Joan Villarroya
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 143-152 (2022)
Lipodystrophy is a major disturbance in people living with HIV-1 (PLWH). Several systemic alterations in PLWH are reminiscent of those that occur in ageing. It is unknown whether the lipodystrophy in PLWH is the consequence of accelerated ageing in a
Externí odkaz:
https://doaj.org/article/61ce931dcec94416a091169e2a981474
Autor:
Laura M. Laiglesia, Xavier Escoté, Neira Sáinz, Elisa Felix-Soriano, Eva Santamaría, María Collantes, Marta Fernández-Galilea, Ignacio Colón-Mesa, Leyre Martínez-Fernández, Tania Quesada-López, Sergio Quesada-Vázquez, Carlos Rodríguez-Ortigosa, José M. Arbones-Mainar, Ángela M. Valverde, J Alfredo Martínez, Jesmond Dalli, Laura Herrero, Silvia Lorente-Cebrián, Francesc Villarroya, María J. Moreno-Aliaga
Publikováno v:
Molecular Metabolism, Vol 74, Iss , Pp 101749- (2023)
Objective: Maresin 1 (MaR1) is a docosahexaenoic acid-derived proresolving lipid mediator with insulin-sensitizing and anti-steatosis properties. Here, we aim to unravel MaR1 actions on brown adipose tissue (BAT) activation and white adipose tissue (
Externí odkaz:
https://doaj.org/article/22820310ff864737969835f5345a7e5e
Autor:
Jessica Latorre, Ramon Díaz-Trelles, Ferran Comas, Aleix Gavaldà-Navarro, Edward Milbank, Nathalia Dragano, Samantha Morón-Ros, Rajesh Mukthavaram, Francisco Ortega, Anna Castells-Nobau, Núria Oliveras-Cañellas, Wifredo Ricart, Priya P. Karmali, Kiyoshi Tachikawa, Pad Chivukula, Francesc Villarroya, Miguel López, Marta Giralt, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 599-613 (2022)
Circulating lipopolysaccharide-binding protein (LBP) is increased in individuals with liver steatosis. We aimed to evaluate the possible impact of liver LBP downregulation using lipid nanoparticle-containing chemically modified LBP small interfering
Externí odkaz:
https://doaj.org/article/2318b693c0cb490ab904a421bf554622
Autor:
Moisés Castellá, Albert Blasco-Roset, Marion Peyrou, Aleix Gavaldà-Navarro, Joan Villarroya, Tania Quesada-López, Leyre Lorente-Poch, Juan Sancho, Florian Szymczak, Anthony Piron, Sonia Rodríguez-Fernández, Stefania Carobbio, Albert Goday, Pere Domingo, Antonio Vidal-Puig, Marta Giralt, Décio L. Eizirik, Francesc Villarroya, Rubén Cereijo
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106847- (2023)
Summary: Adipose tissue from pheochromocytoma patients acquires brown fat features, making it a valuable model for studying the mechanisms that control thermogenic adipose plasticity in humans. Transcriptomic analyses revealed a massive downregulatio
Externí odkaz:
https://doaj.org/article/28b4ea636229492aaaac613396fa4a6a
Autor:
Jessica Latorre, Francisco Ortega, Núria Oliveras-Cañellas, Ferran Comas, Aina Lluch, Aleix Gavaldà-Navarro, Samantha Morón-Ros, Wifredo Ricart, Francesc Villarroya, Marta Giralt, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 870-879 (2022)
Lipopolysaccharide binding protein (Lbp) has been recently identified as a relevant component of innate immunity response associated to adiposity. Here, we aimed to investigate the impact of adipose tissue Lbp on weight gain and white adipose tissue
Externí odkaz:
https://doaj.org/article/f9dbfee1ff5c4a26b586d69304553e65
Autor:
Cristina Garcia-Beltran, Artur Navarro-Gascon, Abel López-Bermejo, Tania Quesada-López, Francis de Zegher, Lourdes Ibáñez, Francesc Villarroya
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionMeteorin-like (METRNL) is a hormonal factor released by several tissues, including thermogenically active brown and beige adipose tissues. It exerts multiple beneficial effects on metabolic and cardiovascular systems in experimental model
Externí odkaz:
https://doaj.org/article/111074e1e8054887bb93ec1b58163c42