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Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:2235-2238
The crucial E-ring of camptothecin has been modified to afford the homologous β-hydroxylactone derivative BN 80245. This compound, which is more stable than camptothecin, remains a potent inhibitor of both cell growth and topoisomerase I.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34b0331733e1db17b65f6b0b2a5fc072
https://doi.org/10.1016/s0960-894x(97)00398-3
https://doi.org/10.1016/s0960-894x(97)00398-3
