Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Frances W J, Beck"'
Publikováno v:
Immunology & Cell Biology. 88:497-499
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d16edbd3c65e43224bdcb38713c63c
https://doi.org/10.1038/icb.2010.10
https://doi.org/10.1038/icb.2010.10
Publikováno v:
Toxicology letters. 166(3)
Zinc deficiency decreased cellular immune response. Zinc supplementation reverses this response. High concentration of zinc intake is reported to alter immune response. We hypothesize that higher concentration of zinc adversely affects T-cell immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50e28d232a958b3fc35a76e212f2804f
https://pubmed.ncbi.nlm.nih.gov/16930873
https://pubmed.ncbi.nlm.nih.gov/16930873
Publikováno v:
Experimental Biology and Medicine. 145:135-141
Summary1. Many acute irritants, e.g., turpentine, mimicked Freund's adjuvant (FA) in causing rapid depression of hexobarbital and cyclophosphamide metabolism in rats in vivo.2. Metabolism of cyclophosphamide and aminopyrine in vitro by liver homogena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e8159914841ecc3d41ad59dd0fed0c
https://doi.org/10.3181/00379727-145-37763
https://doi.org/10.3181/00379727-145-37763
Publikováno v:
Agents and Actions. 5:541-548
(1) A strategy is described for investigating agents such asN-acetylcysteine or penicillamine that might be used as adjuvant therapy with cyclophosphamide, to lessen the toxic side-effects of this latter drug caused by some of its metabolites. (2) Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::419b1457b6729780c921f15d326e9d2f
https://doi.org/10.1007/bf01972692
https://doi.org/10.1007/bf01972692
Publikováno v:
Agents and Actions. 4:34-43
Circumstantial evidence is presented that chloracetaldehyde is generated from cyclophosphamide by chemical oxidation in vitro with peroxide and might possibly be formed in vivo as a product of cyclophosphamide bioactivation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa03418d2478c7e02a91cabe937cd06a
https://doi.org/10.1007/bf01965490
https://doi.org/10.1007/bf01965490
Publikováno v:
Endocrinology. 114:624-628
Previous studies of the sodium-potassium pump in the deoxycorticosterone (DOC)-salt (DS) model of hypertension yielded contrasting results, some investigators reporting increased and others finding decreased pump activity. To test the possibility tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b691354cefb5a6ee0dcb1c6a653a1b15
https://doi.org/10.1210/endo-114-2-624
https://doi.org/10.1210/endo-114-2-624
Publikováno v:
Experimental Biology and Medicine. 151:615-622
Several methods of inducing experimental allergic encephalomyelitis (EAE) in rats were examined using different (i) rat strains, (ii) combinations of encephalitogen with different adjuvants, and (iii) sites of encephalitogen inoculation. The time cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52cfc302ad050d2c834107bffb599174
https://doi.org/10.3181/00379727-151-39272
https://doi.org/10.3181/00379727-151-39272
Autor:
Michael W. Whitehouse, Carl M. Pearson, Frances W. J. Beck, Arthur Lorber, Werner A. Baumgartner
Publikováno v:
Experimental Biology and Medicine. 145:625-630
Summary(1) The impaired drug metabolism, associated with adjuvant arthritis, spontaneously returns towards normal after 6 weeks. (2) The plasma protein thiol titer falls precipitiously with onset of arthritis but eventually returns to normal. (3) Bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127c9331738bc8d5cdfb5ea2e9444484
https://doi.org/10.3181/00379727-145-37863
https://doi.org/10.3181/00379727-145-37863
Publikováno v:
Agents and Actions. 4:117-124
The potential immunosuppressant activity of the following compounds derived from cyclophosphamide (CPA) was evaluated: 8 known metabolites, oxidation products and hydrolytic products of CPA containing the mustard moiety; the mixture of alkylating pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56db39c243b51f2a97664aca91bb7c0b
https://doi.org/10.1007/bf01966821
https://doi.org/10.1007/bf01966821
Publikováno v:
Biochemical Pharmacology. 22:2453-2468
After the injection of a variety of arthritogenic adjuvants into male Wistar rats, hepatic activation of cyclophosphamide and isophosphamide is rapidly and profoundly depressed. This selective injury is largely reversible with phenobarbital and princ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b2650eb3756ac685a347b244cc1b3f
https://doi.org/10.1016/0006-2952(73)90348-1
https://doi.org/10.1016/0006-2952(73)90348-1