Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Frances T. Pagel"'
Autor:
Natalya S. Chernyaeva, Frances T. Pagel, Alexey L. Arkov, Emanuel J. Murgola, Klas O. F. Hedenstierna
Publikováno v:
The Ribosome
This chapter provides an overview of recent work that has demonstrated the roles of two rRNA functional sites, one in 16S rRNA (the small subunit) and the other in 23S rRNA (the large subunit), in release factor (RF) binding and in catalysis of pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c3c85335a99131936693272ff588c8f
https://doi.org/10.1128/9781555818142.ch41
https://doi.org/10.1128/9781555818142.ch41
Autor:
Alexey L. Arkov, Frances T. Pagel, Song Q. Zhao, Wenbing Xu, Kathryn A. Hijazi, Emanuel J. Murgola
Publikováno v:
Biochemistry and Cell Biology. 73:925-931
To screen for ribosomal RNA mutants defective in peptide chain termination, we have been looking for rRNA mutants that exhibit different patterns of suppression of nonsense mutations and that do not suppress missense mutations at the same positions i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a39e2908b1bb67c9686f59c7e02ad71
https://doi.org/10.1139/o95-100
https://doi.org/10.1139/o95-100
Autor:
B.H. Mims, D. Brechemier-Baey, P.M. Sörensen, Kathryn A. Hijazi, Emanuel J. Murgola, Frances T. Pagel, Richard H. Buckingham
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1050:259-262
The base sequence around nonsense codons affects the efficiency of nonsense codon suppression. Published data, comparing different nonsense sites in a mRNA, implicate the two bases downstream of the nonsense codon as major determinants of suppression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a31a7b4b196f33837d4b504e3f6c572
https://doi.org/10.1016/0167-4781(90)90177-4
https://doi.org/10.1016/0167-4781(90)90177-4
Publikováno v:
Journal of molecular biology. 267(5)
RNA sites that contain unpaired or mismatched nucleotides can be interaction sites for other macromolecules. C1054, a virtually universally conserved nucleotide in the 16 S (small subunit) ribosomal RNA of Escherichia coli, is part of a highly conser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267594e20e6c1c6c9584a5a6a35c4344
https://pubmed.ncbi.nlm.nih.gov/9150400
https://pubmed.ncbi.nlm.nih.gov/9150400
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 92(26)
A role for rRNA in peptide chain termination was indicated several years ago by isolation of a 168 rRNA (small subunit) mutant of Escherichia coli that suppressed UGA mutations. In this paper, we describe another interesting rRNA mutant, selected as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8b167dd31a13981dbe6e6daa1bfc21
https://pubmed.ncbi.nlm.nih.gov/8618891
https://pubmed.ncbi.nlm.nih.gov/8618891
Publikováno v:
Biochimie. 71:729-739
Missense and nonsense suppressor tRNAs, selected for their ability to read a new triplet codon, were observed to suppress one or more frameshift mutations in trpA of Escherichia coli. Two of the suppressible frameshift mutants, trpA8 and trpA46AspPR3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf8b4f077b515d03b404559deff4a1c
https://doi.org/10.1016/0300-9084(89)90089-8
https://doi.org/10.1016/0300-9084(89)90089-8
Publikováno v:
Journal of molecular biology. 175(1)
After our first observation of codon context effects in missense suppression (Murgola & Pagel, 1983), we measured the suppression of missense mutations at two positions in trpA in Escherichia coli. The suppressible codons in the trpA messenger RNA we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff4df5d6c7d2a5f7236a1288510a709
https://pubmed.ncbi.nlm.nih.gov/6374155
https://pubmed.ncbi.nlm.nih.gov/6374155
Autor:
Emanuel J. Murgola, Frances T. Pagel
Publikováno v:
Journal of molecular biology. 138(4)
In order to provide evidence concerning the nature of codon recognition by isoaccepting transfer RNAs of Escherichia coli in vivo, we have carried out genetic experiments with appropriate glycine tRNA mutants that display altered coding specificities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f0ef6732232096fb9747802df4e333
https://pubmed.ncbi.nlm.nih.gov/6157831
https://pubmed.ncbi.nlm.nih.gov/6157831
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 80(16)
In a previous publication, an unusual UGG-reading missense suppressor caused by insertion of an extra adenylate residue in the anticodon loop of an Escherichia coli glycine tRNA was described. In this study, we provide in vivo evidence that the addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0585b3de17977fa035e782ac2ef9ed92
https://pubmed.ncbi.nlm.nih.gov/6348778
https://pubmed.ncbi.nlm.nih.gov/6348778