Transfer Phenomena of Nanoliposomes by Live Imaging of Primary Cultures of Cortical Neurons

Autor: Elodie Passeri, Philippe Bun, Kamil Elkhoury, Michel Linder, Catherine Malaplate, Frances T. Yen, Elmira Arab-Tehrany

Publikováno v: Pharmaceutics, Vol 14, Iss 10, p 2172 (2022)

Soft nanoparticles, and in particular, nanoliposomes (NL), have attracted increasing interest for their use in food, nutraceuticals, and in particular, in pharmaceutics for drug delivery. Recent data using salmon lecithin NL suggest that these NL, ri

Externí odkaz: https://doaj.org/article/6cfc98cabc66432fb2decb512cdc392c

Disialylated apolipoprotein C-III proteoform is associated with improved lipids in prediabetes and type 2 diabetes1[S]

Autor: Juraj Koska, Hussein Yassine, Olgica Trenchevska, Shripad Sinari, Dawn C. Schwenke, Frances T. Yen, Dean Billheimer, Randall W. Nelson, Dobrin Nedelkov, Peter D. Reaven

Publikováno v: Journal of Lipid Research, Vol 57, Iss 5, Pp 894-905 (2016)

The apoC-III proteoform containing two sialic acid residues (apoC-III2) has different in vitro effects on lipid metabolism compared with asialylated (apoC-III0) or the most abundant monosialylated (apoC-III1) proteoforms. Cross-sectional and longitud

Externí odkaz: https://doaj.org/article/d090ab72382943adb80576d75f82fe1e

Alzheimer’s Disease

Autor: Elodie Passeri, Kamil Elkhoury, Margaretha Morsink, Kerensa Broersen, Michel Linder, Ali Tamayol, Catherine Malaplate, Frances T. Yen, Elmira Arab-Tehrany

Publikováno v: International journal of molecular sciences. 23(22)

Alzheimer’s disease (AD) is the most frequent case of neurodegenerative disease and is becoming a major public health problem all over the world. Many therapeutic strategies have been explored for several decades; however, there is still no curativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad80700be73ff88353b89d70e42619c7
http://www.scopus.com/inward/record.url?scp=85142640088&partnerID=8YFLogxK

Lipolysis-Stimulated Lipoprotein Receptor Acts as Sensor to Regulate ApoE Release in Astrocytes

Autor: Ameziane Herzine, Ghita Sekkat, Sandra Kaminski, Gaetano Calcagno, Sandrine Boschi-Muller, Hela Safi, Catherine Corbier, Sophie Siest, Thomas Claudepierre, Frances T. Yen

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8630
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (15), pp.8630. ⟨10.3390/ijms23158630⟩

International audience; Astroglia play an important role, providing de novo synthesized cholesterol to neurons in the form of ApoE-lipidated particles; disruption of this process can increase the risk of Alzheimer’s disease. We recently reported th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9baaf1475512a0a8ba726a063719156
https://pubmed.ncbi.nlm.nih.gov/35955777

The Association of Human Apolipoprotein C-III Sialylation Proteoforms with Plasma Triglycerides.

Autor: Hussein N Yassine, Olgica Trenchevska, Ambika Ramrakhiani, Aarushi Parekh, Juraj Koska, Ryan W Walker, Dean Billheimer, Peter D Reaven, Frances T Yen, Randall W Nelson, Michael I Goran, Dobrin Nedelkov

Publikováno v: PLoS ONE, Vol 10, Iss 12, p e0144138 (2015)

Apolipoprotein C-III (apoC-III) regulates triglyceride (TG) metabolism. In plasma, apoC-III exists in non-sialylated (apoC-III0a without glycosylation and apoC-III0b with glycosylation), monosialylated (apoC-III1) or disialylated (apoC-III2) proteofo

Externí odkaz: https://doaj.org/article/4263e407812d451db09dac2570d33695