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Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells
Autor:
Scott E. Fraser, Frances Seo, Jesse Yang, Jason A. Junge, Nicholas A. Graham, Sydney Parrish, Pin Wang, Alireza Delfarah, Si Li, John Mac
Publikováno v:
J Biol Chem
Cellular senescence is a mechanism by which cells permanently withdraw from the cell cycle in response to stresses including telomere shortening, DNA damage, or oncogenic signaling. Senescent cells contribute to both age-related degeneration and hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb51935d22effa76a511c682548feba
https://doi.org/10.1074/jbc.ra118.005806
https://doi.org/10.1074/jbc.ra118.005806
