Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Frances S. Grudzinska"'
Autor:
Frances S. Grudzinska, Alice Jasper, Elizabeth Sapey, David R. Thickett, Claudio Mauro, Aaron Scott, Jonathan Barlow
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Neutrophil responses are critical during inflammatory and infective events, and neutrophil dysregulation has been associated with poor patient outcomes. Immunometabolism is a rapidly growing field that has provided insights into cellular functions in
Externí odkaz:
https://doaj.org/article/59086772f925458b814c28481acc056c
Autor:
Kylie B. R. Belchamber, Onn S. Thein, Jon Hazeldine, Frances S. Grudzinska, Aduragbemi A. Faniyi, Michael J. Hughes, Alice E. Jasper, Kay Por Yip, Louise E. Crowley, Sebastian T. Lugg, Elizabeth Sapey, Dhruv Parekh, David R. Thickett, Aaron Scott
Publikováno v:
Cells, Vol 11, Iss 18, p 2901 (2022)
Rationale: Infection with the SARS-CoV2 virus is associated with elevated neutrophil counts. Evidence of neutrophil dysfunction in COVID-19 is based on transcriptomics or single functional assays. Cell functions are interwoven pathways, and understan
Externí odkaz:
https://doaj.org/article/6e499c61195847cd87688b285c0e40fd
Autor:
Asim Ahmed, Sayed A Alderazi, Rumaisa Aslam, Barooq Barkat, Bethan L Barker, Rahul Bhat, Samuel Cassidy, Louise E Crowley, Davinder PS Dosanjh, Hussain Ebrahim, Najla Elndari, Claudia Gardiner, Atena Gogokhia, Frances S Grudzinska, Megha T Gurung, Terry Hughes, Iyad Ismail, Natasha Iredale, Sannaan Irshad, Sarah Johnson, Diana Kavanagh, Thomas Knight, Alana Livesey, Sebastian T Lugg, Manoj Marathe, Andrew McDougall, Wasim Nawaz, Kimberly Nettleton, Lauren O’Flynn, Kelvin Okoth, Dhruv Parekh, Rita Perry, Elizabeth J Pudney, Ambreen Sadiq, Olutobi Soge, Rhania Soloman, Marina Soltan, Martin Strecker, Onn S Thein, David Thickett, Ajit Thomas, Riah Thornton
Publikováno v:
Clinical medicine (London, England). 22(1)
Severity scores in pneumonia and sepsis are being applied to SARS-CoV-2 infection. We aimed to assess whether these severity scores are accurate predictors of early adverse outcomes in COVID-19.We conducted a multicentre observational study of hospit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071bc5445904c2b3032c48543354a3e6
https://pubmed.ncbi.nlm.nih.gov/35078796
https://pubmed.ncbi.nlm.nih.gov/35078796
Publikováno v:
BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Introduction Community-acquired pneumonia has high mortality and is associated with significant healthcare costs. In older adults with community-acquired pneumonia neutrophil dysfunction has been identified and is associated with poor outcomes for pa
Externí odkaz:
https://doaj.org/article/5a33216c7c434109918e7e82f56fbccd
Autor:
Kerrie Aldridge, Dhruv Parekh, Elizabeth Sapey, David R Thickett, Peter Nightingale, Frances S Grudzinska, Sian Hughes, Mansoor Bangash, Rachel Dancer, Jaimin Patel, Davinder P Dosanjh
Publikováno v:
BMJ Open Respiratory Research, Vol 6, Iss 1 (2019)
Background Community-acquired pneumonia (CAP) is a leading cause of sepsis worldwide. Prompt identification of those at high risk of adverse outcomes improves survival by enabling early escalation of care. There are multiple severity assessment tools
Externí odkaz:
https://doaj.org/article/1ab7a958dccf426e9916fac150114804