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pro vyhledávání: '"Frances S Turner"'
Autor:
Ashley M Whittington, Frances S Turner, Friedrich Baark, Sam Templeman, Daniela E Kirwan, Candice Roufosse, Nitya Krishnan, Brian D Robertson, Deborah L W Chong, Joanna C Porter, Robert H Gilman, Jon S Friedland
Publikováno v:
PLoS Pathogens, Vol 19, Iss 7, p e1011495 (2023)
Mycobacterium tuberculosis (M.tb) infection causes marked tissue inflammation leading to lung destruction and morbidity. The inflammatory extracellular microenvironment is acidic, however the effect of this acidosis on the immune response to M.tb is
Externí odkaz:
https://doaj.org/article/f0eefa760a3340aa8ca68867ab1b8d6d
Publikováno v:
Genome Biology
POCUS (prioritization of candidate genes using statistics) is a novel computational approach to prioritize candidate disease genes that is based on over-representation of functional annotation between loci for the same disease.
Here we present P
Here we present P
Publikováno v:
Genome Biology. 4:R75
Here we present POCUS (prioritization of candidate genes using statistics), a novel computational approach to prioritize candidate disease genes that is based on over-representation of functional annotation between loci for the same disease. We show
Autor:
Frances S Turner
Publikováno v:
BMC Bioinformatics. 6(Suppl 3):S14
Although much work has been done in the linkage mapping of many common, genetically complex diseases studies have typically identified disease susceptibility regions of tens of megabases, rather than individual genes [1]. Typically genes are prioriti