Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Frances Platt"'
Autor:
William Evans, Marc Patterson, Frances Platt, Christina Guldberg, Toni Mathieson, Jessica Pacey, the Core Working Group for the Delphi Study
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-22 (2021)
Abstract Background Several scales have been developed in the past two decades to evaluate Niemann–Pick disease Type C (NPC) severity in clinical practice and trials. However, a lack of clarity concerning which scale to use in each setting is preve
Externí odkaz:
https://doaj.org/article/46cfd0e5c0d2451ea0832be576c10057
Autor:
Antonino Puglisi, Noemi Bognanni, Graziella Vecchio, Ece Bayir, Peter van Oostrum, Dawn Shepherd, Frances Platt, Erik Reimhult
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 573 (2023)
Core–shell superparamagnetic iron oxide nanoparticles hold great promise as a theranostic platform in biological systems. Herein, we report the biological effect of multifunctional cyclodextrin-appended SPIONs (CySPION) in mutant Npc1-deficient CHO
Externí odkaz:
https://doaj.org/article/541d52a1e213425bb686f63949ef58b3
Autor:
Erdinc Sezgin, Fatma Betul Can, Falk Schneider, Mathias P. Clausen, Silvia Galiani, Tess A. Stanly, Dominic Waithe, Alexandria Colaco, Alf Honigmann, Daniel Wüstner, Frances Platt, Christian Eggeling
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 2, Pp 299-309 (2016)
Cholesterol (Chol) is a crucial component of cellular membranes, but knowledge of its intracellular dynamics is scarce. Thus, it is of utmost interest to develop tools for visualization of Chol organization and dynamics in cells and tissues. For this
Externí odkaz:
https://doaj.org/article/7c67c1889c1b4f23aba5ef92dfd792d2
Autor:
Danielle te Vruchte, Andrea Sturchio, David A. Priestman, Panagiota Tsitsi, Ellen Hertz, Mattias Andréasson, Ioanna Markaki, Kerri‐Lee Wallom, Frances Platt, Per Svenningsson
Publikováno v:
Movement Disorders. 37:2129-2134
Alteration in glycosphingolipids (GSLs) in Parkinson's disease (PD) still needs to be determined.We evaluated if PD subjects show abnormal GSLs levels compared to healthy controls (HC) and if GSLs correlate with clinical features.We analyzed GSLs and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e773bdbc922bd81561baab6391c8d0b1
https://doi.org/10.1002/mds.29163
https://doi.org/10.1002/mds.29163
Autor:
Emil K. Gustavsson, Siddharth Sethi, Yujing Gao, Jonathan W. Brenton, Sonia García-Ruiz, David Zhang, Raquel Garza, Regina H. Reynolds, James R. Evans, Zhongbo Chen, Melissa Grant-Peters, Hannah Macpherson, Kylie Montgomery, Rhys Dore, Anna I. Wernick, Charles Arber, Selina Wray, Sonia Gandhi, Julian Esselborn, Cornelis Blauwendraat, Christopher H. Douse, Anita Adami, Diahann A.M. Atacho, Antonina Kouli, Annelies Quaegebeur, Roger A. Barker, Elisabet Englund, Frances Platt, Johan Jakobsson, Nicholas W. Wood, Henry Houlden, Harpreet Saini, Carla F. Bento, John Hardy, Mina Ryten
The human genome contains numerous duplicated regions, such as parent-pseudogene pairs, causing sequencing reads to align equally well to either gene. The extent to which this ambiguity complicates transcriptomic analyses is currently unknown. This i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aef8c29ea97f0d880be74d785ceca3d
https://doi.org/10.1101/2022.10.21.513169
https://doi.org/10.1101/2022.10.21.513169
Autor:
Taylor Fields, Tatiana Bremova-Ertl, Ian Billington, Grant Churchill, William Evans, Cassandra Fields, Antony Galione, Richard Kay, Toni Matheison, Kyriakos Martakis, Marc Patterson, Frances Platt, Mallory Factor, Michael Strupp
Background Niemann-Pick disease type C (NPC) is a rare autosomal recessive neurodegenerative lysosomal disease characterized by multiple symptoms such as progressive cerebellar ataxia and cognitive decline. The modified amino acid N-acetyl-leucine ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8087fb7720d472abf447d34c197b8c12
https://doi.org/10.21203/rs.3.rs-2048685/v1
https://doi.org/10.21203/rs.3.rs-2048685/v1
Autor:
Victoria Stavrou, Livingstone Fultang, Sarah Booth, Daniele De Simone, Arekdiusz Bartnik, Ugo Scarpa, Luciana Gneo, Silvia Panetti, Sandeep Potluri, Meaad Almowaled, Jonathan Barlow, Andris Jankevics, Gavin Lloyd, Andrew Southam, David A. Priestman, Paul Cheng, Warwick Dunn, Frances Platt, Hitoshi Endou, Charles Craddock, Karen Keeshan, Francis Mussai, Carmela De Santo
Acute myeloid leukaemia (AML) creates an immunosuppressive environment to conventional T cells through Arginase 2 (ARG2)-induced arginine depletion. We identify that AML blasts release the acute phase protein serum amyloid A (SAA), which acts in an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7194899688dbd455a6f962fac909168
https://eprints.gla.ac.uk/277780/1/277780.pdf
https://eprints.gla.ac.uk/277780/1/277780.pdf
Autor:
Rumaitha Al Hosni, Emilio Agostinelli, Zeki Ilkan, Lara F. Scofano, Kathryn Acheson, Andrew MacDonald, Dean Rivers, Martin Gunthorpe, Frances Platt, Paolo Tammaro
Publikováno v:
Biophysical Journal. 122:458a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8728cc1e0ed1560ff23e2446844da0c
https://doi.org/10.1016/j.bpj.2022.11.2463
https://doi.org/10.1016/j.bpj.2022.11.2463
Autor:
Frances Platt, Nick Platt
This new volume of Methods in Cell Biology looks at methods for lysosomes and lysosomal diseases. Chapters focus upon practical experimental protocols to guide researchers through the analysis of multiple aspects of lysosome biology and function. In
Autor:
Frances Platt
Publikováno v:
Index on Censorship. 32:219-222
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63fc6dd24d3cebce0e5430f7cdab9421
https://doi.org/10.1080/03064220308537239
https://doi.org/10.1080/03064220308537239