Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Frances Maher"'
Autor:
Skyler Kuhn, Michael M Gottesman, Frances Maher, Da Yin, Robert W. Robey, Jordan M. Hotz, Sachi Horibata, Ruchi P. Patel
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100917-(2021)
Translational Oncology, Vol 14, Iss 1, Pp 100917-(2021)
Highlights • Subpopulations of cisplatin-resistant cells are cross-resistant to anti-microtubule drugs. • Resistance mechanisms in cisplatin-resistant ovarian cancer cells are diverse. • Increased TNF and NFκB signaling found in cisplatin-resi
Publikováno v:
Biochemical and Biophysical Research Communications. 186:1129-1137
The GLUT3 facilitative glucose transporter protein was found to be expressed in rat L6 muscle cells. It was detected at both the myoblast and myotube stage. GLUT3 protein content per mg of total membrane protein increased significantly during L6 cell
Publikováno v:
Biochemical and Biophysical Research Communications. 182:703-711
Polyclonal anti-peptide antisera were raised to the C-terminal sequence of mouse- and human-GLUT3 glucose transporter isoforms. GLUT3 protein and mRNA expression were investigated by Western blot and Northern blot assays, in a range of tissues and ce
Publikováno v:
Molecular and Cellular Neuroscience. 2:351-360
The brain is dependent on glucose as an energy source and thus requires the expression of glucose transporter proteins to enable passage of glucose across both the endothelial cells of the blood-brain barrier and the plasma membranes of neurons and g
Autor:
Leonard C. Harrison, Frances Maher
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1089:27-32
Glucose deprivation increases the steady-state levels of mRNA for the rat brain/HepG2-type glucose transporter (GLUT1) in L6 myocytes. Glucose deprivation also inhibits N-linked glycosylation. We therefore investigated a possible relationship between
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 8(13)
Glucose is the principal energy source for the mammalian brain. The presence of glucose transport proteins is essential to supply glucose to the neurons and glia within the brain. At least three glucose transporter isoforms have now been identified,
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 13(2)
Two glucose transporter (GLUT) isoforms have been identified in brain. The GLUT1 isoform is abundant in cerebral microvessels and may be present in glia and neurons, whereas GLUT3 is probably the major neuronal glucose transporter. This study investi
Autor:
Leonard C. Harrison, Frances Maher
Publikováno v:
Diabetologia. 33(11)
Glucose deprivation of L6 myocytes results in the upregulation of glucose transporter activity, protein and mRNA. We have investigated the downregulation of transporter gene expression by glucose and other hexoses in glucose-deprived L6 myocytes. Glu
Autor:
Leonard C. Harrison, Frances Maher
Publikováno v:
Biochemical and biophysical research communications. 171(1)
Chronic exposure of L6 myocytes to insulin/IGF-1 or glucose deprivation results in an increase in the level of brain-type glucose transporter (GLUT1) mRNA. We have investigated the effects of insulin and glucose deprivation on GLUT1 mRNA stability. T
Autor:
Frances Maher, P.A. Janssens
Publikováno v:
General and comparative endocrinology. 61(1)
Glucagon increases the rate of glycogenolysis in in vitro cultures of hepatic tissue from the axolotl Ambystoma mexicanum. The hormone causes an increase in the concentration of cyclic AMP in the tissue which is followed by activation of glycogen pho