Výsledky vyhledávání - "Frances M. Sirotnak"

Synthesis and antifolate evaluation of the aminopterin analogue with a bicyclo[2.2.2]octane ring in place of the benzene ring

Autor: James R. Piper, Robert C. Reynolds, Cheryl A. Johnson, Frances M. Sirotnak

Publikováno v: European Journal of Medicinal Chemistry. 36:237-242

N-[4-[[2,4-diamino-6-pteridinyl)methyl]amino]bicyclo[2.2.2]octane-1-carbonyl]-L-glutamic acid (1) was synthesized and tested for antifolate activity. N-(4-Aminobicyclo[2.2.2]octane-1-carbonyl-L-glutamic acid dimethyl ester (6), the side chain precurs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36ebe8a91cf790e5d2af894bbb55105d
https://doi.org/10.1016/s0223-5234(01)01224-7

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ChemInform Abstract: Synthesis and Antifolate Evaluation of the Aminopterin Analogue with a Bicyclo[2.2.2]octane Ring in Place of the Benzene Ring

Autor: Robert C. Reynolds, Cheryl A. Johnson, Frances M. Sirotnak, James R. Piper

Publikováno v: ChemInform. 32

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8dd70a5743c5c622ba9348b1bd00a3e9
https://doi.org/10.1002/chin.200140192

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