Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Frances M. K. Williams"'
Autor:
David L Bennett, Frances M K Williams, Maxim B Freidin, Jelle Vehof, Amber Rhee, Isabelle Granville Smith, Roger Compte, Ayrun Nessa, Samuel Wadge
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Objective The chronic pain syndromes (CPS) include syndromes such as chronic widespread pain (CWP), dry eye disease (DED) and irritable bowel syndrome (IBS). Highly prevalent and lacking pathognomonic biomarkers, the CPS are known to cluster in indiv
Externí odkaz:
https://doaj.org/article/44cbe663c96f40cea9e06a51575c5b50
Autor:
Roger Compte, Maxim B. Freidin, Isabelle Granville Smith, Christine L. Le Maitre, Dovile Vaitkute, Ayrun Nessa, Genevieve Lachance, Frances M. K. Williams
Publikováno v:
JOR Spine, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Introduction Intervertebral disc degeneration and Modic change are the main spinal structural changes associated with chronic low back pain (LBP). Both conditions are thought to manifest local inflammation and if inflammatory proteins transl
Externí odkaz:
https://doaj.org/article/03d5f80b7a6e49d1abd0590b447f48e3
Autor:
Melody Kasher, Maxim B. Freidin, Frances M. K. Williams, Gregory Livshits, CHARGE Inflammation Working Group
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 563 (2024)
Inflammageing is a condition of perpetual low-grade inflammation induced by ageing. Inflammageing may be predicted by the C-reactive protein (CRP) or by a recently described biomarker which measures N-glycosylated side chains of the carbohydrate comp
Externí odkaz:
https://doaj.org/article/112ba8f722a74621936487af4ddb0c10
Autor:
Morag A Lewis, Jennifer Schulte, Lois Matthews, Kenneth I Vaden, Claire J Steves, Frances M K Williams, Bradley A Schulte, Judy R Dubno, Karen P Steel
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011058 (2023)
Adult-onset progressive hearing loss is a common, complex disease with a strong genetic component. Although to date over 150 genes have been identified as contributing to human hearing loss, many more remain to be discovered, as does most of the unde
Externí odkaz:
https://doaj.org/article/60402f1aa5f14554a3436cc295e14c8e
Autor:
Philippa M. Wells, Daniel D. Sprockett, Ruth C. E. Bowyer, Yuko Kurushima, David A. Relman, Frances M. K. Williams, Claire J. Steves
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The oral microbiota is emerging as an influential factor of host physiology and disease state. Factors influencing oral microbiota composition have not been well characterised. In particular, there is a lack of population-based studies. We u
Externí odkaz:
https://doaj.org/article/189247387ab94ca08f49bb85b9ed73be
Autor:
Ellen J. Thompson, Dylan M. Williams, Alex J. Walker, Ruth E. Mitchell, Claire L. Niedzwiedz, Tiffany C. Yang, Charlotte F. Huggins, Alex S. F. Kwong, Richard J. Silverwood, Giorgio Di Gessa, Ruth C. E. Bowyer, Kate Northstone, Bo Hou, Michael J. Green, Brian Dodgeon, Katie J. Doores, Emma L. Duncan, Frances M. K. Williams, OpenSAFELY Collaborative, Andrew Steptoe, David J. Porteous, Rosemary R. C. McEachan, Laurie Tomlinson, Ben Goldacre, Praveetha Patalay, George B. Ploubidis, Srinivasa Vittal Katikireddi, Kate Tilling, Christopher T. Rentsch, Nicholas J. Timpson, Nishi Chaturvedi, Claire J. Steves
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Current understanding of Long COVID is limited, in part, due to lack of evidence from population-representative studies. Here, the authors analyse data from ten UK population-based studies and electronic health records, and find wide variation in the
Externí odkaz:
https://doaj.org/article/58a3aca8cd4540fa97e10655576a3a90
Autor:
Sook Yan Lee, Fowzia Ibrahim, Brian D. M. Tom, Elena Nikiphorou, Frances M. K. Williams, Heidi Lempp, David L. Scott
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)
Abstract Background Clinical trials show intensive treatment to induce remission is effective in patients with highly active rheumatoid arthritis (RA). The TITRATE trial showed that the benefits of intensive treatment also extend to moderately active
Externí odkaz:
https://doaj.org/article/0ebf5cdfa430431e922860b4616292ce
Autor:
Helena R. R. Wells, Fatin N. Zainul Abidin, Maxim B. Freidin, Frances M. K. Williams, Sally J. Dawson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Tinnitus is a prevalent condition in which perception of sound occurs without an external stimulus. It is often associated with pre-existing hearing loss or noise-induced damage to the auditory system. In some individuals it occurs frequentl
Externí odkaz:
https://doaj.org/article/028cc4eb36d848ebb89c75495639e87a
Autor:
Andries Paul Nagtegaal, Linda Broer, Nuno R. Zilhao, Johanna Jakobsdottir, Charles E. Bishop, Marco Brumat, Mark W. Christiansen, Massimiliano Cocca, Yan Gao, Nancy L. Heard-Costa, Daniel S. Evans, Nathan Pankratz, Sheila R. Pratt, T. Ryan Price, Christopher Spankovich, Mary R. Stimson, Karen Valle, Dragana Vuckovic, Helena Wells, Gudny Eiriksdottir, Erik Fransen, Mohammad Arfan Ikram, Chuang-Ming Li, W. T. Longstreth, Claire Steves, Guy Van Camp, Adolfo Correa, Karen J. Cruickshanks, Paolo Gasparini, Giorgia Girotto, Robert C. Kaplan, Michael Nalls, John M. Schweinfurth, Sudha Seshadri, Nona Sotoodehnia, Gregory J. Tranah, André G. Uitterlinden, James G. Wilson, Vilmundur Gudnason, Howard J. Hoffman, Frances M. K. Williams, André Goedegebure
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Previous research has shown that genes play a substantial role in determining a person’s susceptibility to age-related hearing impairment. The existing studies on this subject have different results, which may be caused by difficulties in
Externí odkaz:
https://doaj.org/article/7621b23b386a4927bee2760a73494186
Autor:
Maxim B. Freidin, Nathan Cheetham, Emma L. Duncan, Claire J. Steves, Katherine J. Doores, Michael H. Malim, Niccolo Rossi, Janet M. Lord, Paul W. Franks, Alessandra Borsini, Isabelle Granville Smith, Mario Falchi, Carmine Pariante, Frances M. K. Williams
Publikováno v:
Inflammation Research. 72:947-953
Objective and design Fatigue is a prominent symptom in the general population and may follow viral infection, including SARS-CoV2 infection which causes COVID-19. Chronic fatigue lasting more than three months is the major symptom of the post-COVID s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63f97bd840f8ff7a11ed201ef8598f28
https://doi.org/10.1007/s00011-023-01722-2
https://doi.org/10.1007/s00011-023-01722-2