Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Frances L Meredith"'
Publikováno v:
Frontiers in Systems Neuroscience, Vol 9 (2015)
Potassium-selective ion channels are important for accurate transmission of signals from auditory and vestibular sensory end organs to their targets in the central nervous system. During different gravity conditions, astronauts experience altered inp
Externí odkaz:
https://doaj.org/article/c80370ef35e748e2a7c9f48022dd095c
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Inner ear hair cells form synapses with afferent terminals and afferent neurons carry signals as action potentials to the central nervous system. Efferent neurons have their origins in the brainstem and some make synaptic contact with afferent dendri
Externí odkaz:
https://doaj.org/article/30c2586f34ca488b938e7cd36ff70224
Autor:
Frances L. Meredith, Tiffany A. Vu, Brandon Gehrke, Timothy A. Benke, Anna Dondzillo, Katherine J. Rennie
Publikováno v:
Journal of Neurophysiology.
Calyx terminals make afferent synapses with type I hair cells in vestibular epithelia and express diverse ionic conductances that influence action potential generation and discharge regularity in vestibular afferent neurons. Here we investigated the
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
The vestibular system relays information about head position via afferent nerve fibers to the brain in the form of action potentials. Voltage-gated Na+ channels in vestibular afferents drive the initiation and propagation of action potentials, but th
Externí odkaz:
https://doaj.org/article/9bff2c1922714830a6f265b1637ee3be
Publikováno v:
Journal of Neurophysiology. 124:510-524
Action potential firing patterns differ between groups of afferent neurons innervating vestibular epithelia. We investigated the biophysical properties of Na+ currents in specialized vestibular calyx afferent terminals during postnatal development. M
Publikováno v:
J Neurophysiol
Vestibular afferent neurons convey information from hair cells in the peripheral vestibular end organs to central nuclei. Primary vestibular afferent neurons can fire action potentials at high rates and afferent firing patterns vary with the position
In the vestibular periphery neurotransmission between hair cells and primary afferent nerves occurs via specialized ribbon synapses. Type I vestibular hair cells (HCIs) make synaptic contacts with calyx terminals, which enclose most of the HCI basola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf94258fe0709447535b06d81424d0f6
https://europepmc.org/articles/PMC5491709/
https://europepmc.org/articles/PMC5491709/
Publikováno v:
Journal of the Association for Research in Otolaryngology. 13:745-758
Calyx afferent terminals engulf the basolateral region of type I vestibular hair cells, and synaptic transmission across the vestibular type I hair cell/calyx is not well understood. Calyces express several ionic conductances, which may shape postsyn
Publikováno v:
Hearing research. 338
During development of vestibular hair cells, K(+) conductances are acquired in a specific pattern. Functionally mature vestibular hair cells express different complements of K(+) channels which uniquely shape the hair cell receptor potential and filt
Publikováno v:
Journal of neurophysiology. 113(1)
We developed a rodent crista slice to investigate regional variations in electrophysiological properties of vestibular afferent terminals. Thin transverse slices of the gerbil crista ampullaris were made and electrical properties of calyx terminals i