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pro vyhledávání: '"Frances Karla Kusuma"'
Autor:
Frances Karla Kusuma, Aishvaryaa Prabhu, Galen Tieo, Syed Moiz Ahmed, Pushkar Dakle, Wai Khang Yong, Elina Pathak, Vikas Madan, Yan Yi Jiang, Wai Leong Tam, Dennis Kappei, Peter Dröge, H. Phillip Koeffler, Maya Jeitany
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
The kinase inhibitor Ponatinib inhibits an ABL1-JUN signalling axis and alters telomere homeostasis, reduces telomere synthesis, and provokes telomere dysfunction in cancer cells which employ the alternative lengthening of telomeres mechanisms.
Externí odkaz:
https://doaj.org/article/bc2741f3057b451aadd3c9a301ac079d
