Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Frances K Skinner"'
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209429 (2019)
Brain coding strategies are enabled by the balance of synaptic inputs that individual neurons receive as determined by the networks in which they reside. Inhibitory cell types contribute to brain function in distinct ways but recording from specific,
Externí odkaz:
https://doaj.org/article/9e188f181f9c421d9f9b3bb65f06d2ee
Autor:
Vladislav Sekulić, Frances K Skinner
Publikováno v:
eLife, Vol 6 (2017)
Although biophysical details of inhibitory neurons are becoming known, it is challenging to map these details onto function. Oriens-lacunosum/moleculare (O-LM) cells are inhibitory cells in the hippocampus that gate information flow, firing while pha
Externí odkaz:
https://doaj.org/article/d9d5bd78eac54f6e96b5c2fa5c576ae9
Autor:
Katie A Ferguson, Carey Y. L. Huh, Bénédicte eAmilhon, Frédéric eManseau, Sylvain eWilliams, Frances K Skinner
Publikováno v:
Frontiers in Systems Neuroscience, Vol 9 (2015)
Hippocampal theta is a 4-12 Hz rhythm associated with episodic memory, and although it has been studied extensively, the cellular mechanisms underlying its generation are unclear. The complex interactions between different interneuron types, such as
Externí odkaz:
https://doaj.org/article/23b650b07fbc44068a1a353f49f28e89
Publikováno v:
eLife, Vol 4 (2015)
Theoretical ideas have a rich history in many areas of biology, and new theories and mathematical models have much to offer in the future.
Externí odkaz:
https://doaj.org/article/3837edb76f2a4791ab7ad97a199059a0
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e106567 (2014)
Multi-compartmental models of neurons provide insight into the complex, integrative properties of dendrites. Because it is not feasible to experimentally determine the exact density and kinetics of each channel type in every neuronal compartment, an
Externí odkaz:
https://doaj.org/article/dbf9b57f96994b308b1049bffd417d35
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91148 (2014)
Rett syndrome is a severe pediatric neurological disorder caused by loss of function mutations within the gene encoding methyl CpG-binding protein 2 (MeCP2). Although MeCP2 is expressed near ubiquitously, the primary pathophysiology of Rett syndrome
Externí odkaz:
https://doaj.org/article/0c5ad462eb6b49f882a2a4dfdc3cd393
Publikováno v:
Frontiers in Computational Neuroscience, Vol 7 (2013)
The coupling of high frequency oscillations (HFOs; >100 Hz) and theta oscillations (3-12 Hz) in the CA1 region of rats increases during REM sleep, indicating that it may play a role in memory processing. However, it is unclear whether the CA1 region
Externí odkaz:
https://doaj.org/article/a6007614b6864ce197cbb280a940aadc
Autor:
Frances K Skinner
Publikováno v:
F1000Research, Vol 2 (2013)
In 1948, Hodgkin delineated different classes of axonal firing. This has been mathematically translated allowing insight and understanding to emerge. As such, the terminology of ‘Type I’ and ‘Type II’ neurons is commonplace in the Neuroscienc
Externí odkaz:
https://doaj.org/article/e7cc30b72ccc4a578d85a64345ac317b
Autor:
Duluxan eSritharan, Frances K Skinner
Publikováno v:
Frontiers in Computational Neuroscience, Vol 6 (2012)
Theta frequency (4-12 Hz) rhythms in the hippocampus play important roles in learning and memory. CA1 interneurons located at the stratum lacunosum-moleculare and radiatum junction (LM/RAD) are thought to contribute to hippocampal theta population ac
Externí odkaz:
https://doaj.org/article/61b938fb8b87406faa5b608c08017326
Publikováno v:
Frontiers in Neural Circuits, Vol 17 (2023)
Conductance-based models have played an important role in the development of modern neuroscience. These mathematical models are powerful “tools” that enable theoretical explorations in experimentally untenable situations, and can lead to the deve
Externí odkaz:
https://doaj.org/article/9ee3d4f4d820464e90df4009e14b18b0