Zobrazeno 1 - 10
of 4 598
pro vyhledávání: '"Frances K"'
Autor:
Jayne E. Murray, Emanuele Valli, Giorgio Milazzo, Chelsea Mayoh, Andrew J. Gifford, Jamie I. Fletcher, Chengyuan Xue, Nisitha Jayatilleke, Firoozeh Salehzadeh, Laura D. Gamble, Jourdin R. C. Rouaen, Daniel R. Carter, Helen Forgham, Eric O. Sekyere, Joanna Keating, Georgina Eden, Sophie Allan, Stephanie Alfred, Frances K. Kusuma, Ashleigh Clark, Hannah Webber, Amanda J. Russell, Antoine de Weck, Benjamin T. Kile, Martina Santulli, Piergiuseppe De Rosa, Emmy D. G. Fleuren, Weiman Gao, Lorna Wilkinson-White, Jason K. K. Low, Joel P. Mackay, Glenn M. Marshall, Douglas J. Hilton, Federico M. Giorgi, Jan Koster, Giovanni Perini, Michelle Haber, Murray D. Norris
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract MYCN oncogene amplification is frequently observed in aggressive childhood neuroblastoma. Using an unbiased large-scale mutagenesis screen in neuroblastoma-prone transgenic mice, we identify a single germline point mutation in the transcript
Externí odkaz:
https://doaj.org/article/ee532e0c05a8415d9de099a04d9f475c
Autor:
Frances K. Shepherd, Shanley N. Roach, Autumn E. Sanders, Yanan Liu, Dira S. Putri, Rong Li, Nathan Merrill, Mark J. Pierson, Sergei V. Kotenko, Zhongde Wang, Ryan A. Langlois
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT When a virus crosses from one host species to another, the consequences can be devastating. However, animal models to empirically evaluate cross-species transmission can fail to recapitulate natural transmission routes, physiologically relev
Externí odkaz:
https://doaj.org/article/18dd9cd31dc1477fbe597f54b11b48ae
Autor:
Frances K. Pohl
Publikováno v:
Panorama, Vol 0, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/e79028ccb67449569bac6b899dd617ef
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Advancements in linking publicly available census records with vital and administrative records have enabled novel investigations in epidemiology and social history. However, in the absence of unique identifiers, the linkage of th
Externí odkaz:
https://doaj.org/article/954b1a4a51064e18b0007f8645923faf
Publikováno v:
IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 32, Pp 2106-2113 (2024)
Forward sagittal alignment affects physical performance, is associated with pain and impacts the health-related quality of life of the elderly. Interventions that help seniors to improve sagittal balance are needed to inhibit the progression of pain
Externí odkaz:
https://doaj.org/article/0ed62cc8e52d405c84c26de46089bbc2
Autor:
Philip J. Agostinelli, Braxton A. Linder, Katherine A. Frick, Nicholas C. Bordonie, Frances K. Neal, JoEllen M. Sefton
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Rectal core temperature monitoring can help fire services mitigate heat injury but can be invasive and impractical. EQ02 + LifeMonitor provides a non-invasive estimation of core temperature. Therefore, the primary purpose of this study was t
Externí odkaz:
https://doaj.org/article/1d5f419dcb624ff495114705b62faafe
Autor:
Yixing Wu, Paige Mumford, Suzanna Noy, Karen Cleverley, Alicja Mrzyglod, Dinghao Luo, Floris van Dalen, Martijn Verdoes, Elizabeth M. C. Fisher, Frances K. Wiseman
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract Cathepsin B is a cysteine protease that is implicated in multiple aspects of Alzheimer’s disease pathogenesis. The endogenous inhibitor of this enzyme, cystatin B (CSTB) is encoded on chromosome 21. Thus, individuals who have Down syndrome
Externí odkaz:
https://doaj.org/article/fdd398815b864621914e2872780af98c
Autor:
Autumn E. Sanders, Henriette Arnesen, Frances K. Shepherd, Dira S. Putri, Jessica K. Fiege, Mark J. Pierson, Shanley N. Roach, Harald Carlsen, David Masopust, Preben Boysen, Ryan A. Langlois
Publikováno v:
mSphere, Vol 9, Iss 2 (2024)
ABSTRACT Specific pathogen-free (SPF) laboratory mice dominate preclinical studies for immunology and vaccinology. Unfortunately, SPF mice often fail to accurately model human responses to vaccination and other immunological perturbations. Several gr
Externí odkaz:
https://doaj.org/article/87adcac41ea74783bc1ecd64e40dff96
Autor:
Sarah L Ash, Rebecca Orha, Holly Mole, Meg Dinesh-Kumar, Steven P Lee, Frances K Turrell, Clare M Isacke
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 2 (2024)
Background Targeting of solid cancers with chimeric antigen receptor (CAR)-T cells is limited by the lack of suitable tumor-specific antigens and the immunosuppressive, desmoplastic tumor microenvironment that impedes CAR-T cell infiltration, activit
Externí odkaz:
https://doaj.org/article/050b5733a92d4347b81bd4fe65768fbc
Autor:
Andrea Bilger, Eion Plenn, Frances K. Barg, Katharine A. Rendle, William B. Carter, Andrea Lamour-Harrington, Nora Jones, Beth Peterson, John A. Sauceda, Pablo Tebas, Karam Mounzer, David Metzger, Luis J. Montaner, Karine Dubé
Publikováno v:
HIV Research & Clinical Practice, Vol 24, Iss 1 (2023)
Background A feature of HIV cure trials is the need to interrupt treatment to test the efficacy of experimental interventions—a process known as analytical treatment interruptions (ATIs). Objectives We report the experiences of participants after t
Externí odkaz:
https://doaj.org/article/c8680ade81e141539c7c29e476a65d43