Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Frances Hutchings"'
Autor:
Dimitrios Firfilionis, Frances Hutchings, Reza Tamadoni, Darren Walsh, Mark Turnbull, Enrique Escobedo-Cousin, Richard G. Bailey, Johannes Gausden, Aaliyah Patel, Dorian Haci, Yan Liu, Fiona E. N. LeBeau, Andrew Trevelyan, Timothy G. Constandinou, Anthony O'Neill, Marcus Kaiser, Patrick Degenaar, Andrew Jackson
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Neuromodulation is an established treatment for numerous neurological conditions, but to expand the therapeutic scope there is a need to improve the spatial, temporal and cell-type specificity of stimulation. Optogenetics is a promising area of curre
Externí odkaz:
https://doaj.org/article/54a1aa74b23b437eb610dea17c681436
Autor:
Emmanouil Giannakakis, Frances Hutchings, Christoforos A Papasavvas, Cheol E Han, Bernd Weber, Chencheng Zhang, Marcus Kaiser
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0221380 (2020)
Computational studies of the influence of different network parameters on the dynamic and topological network effects of brain stimulation can enhance our understanding of different outcomes between individuals. In this study, a brain stimulation ses
Externí odkaz:
https://doaj.org/article/5ff486e57336403dadc24e92f403258b
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Neuronal circuits can be modelled in detail allowing us to predict the effects of stimulation on individual neurons. Electrical stimulation of neuronal circuits in vitro and in vivo excites a range of neurons within the tissue and measurements of neu
Externí odkaz:
https://doaj.org/article/a7d80e055281446fab45c89667de72c2
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 12, p e1004642 (2015)
Temporal lobe epilepsy (TLE) is a prevalent neurological disorder resulting in disruptive seizures. In the case of drug resistant epilepsy resective surgery is often considered. This is a procedure hampered by unpredictable success rates, with many p
Externí odkaz:
https://doaj.org/article/6cd3a4caa8b34e17a5e386827007467a
Publikováno v:
Neurocomputing
Highlights • Development of a biological neural network model that allows long term simulation of brain activity. • Optimization of the model using multiple techniques that led to a speed-up of X200. • Presentation of alternative simulation fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c0a84fc4e46cbce95f983a73e602a1
https://doi.org/10.1016/j.neucom.2020.01.050
https://doi.org/10.1016/j.neucom.2020.01.050
Autor:
Frances Hutchings, Andrew Jackson, Anthony O'Neill, Nikhil K. Ponon, Darren Walsh, Palmini Rb, Andrew J. Trevelyan, Patrick Degenaar, Johnson El
The recent development of optogenetic tools, to manipulate neuronal activity using light, provides opportunities for novel brain-machine interface (BMI) control systems for treating neurological conditions. An issue of critical importance, therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89e8d1dafe14740363a31ee64112c7fd
https://doi.org/10.1101/2021.04.08.438932
https://doi.org/10.1101/2021.04.08.438932
Autor:
Stuart N. Baker, Sabrina Tardio, Patrick Degenaar, Frances Hutchings, Anthony O'Neill, Marcus Kaiser, Enrique Escobedo-Cousin, Mark O. Cunningham, Yujiang Wang, Boubker Zaaimi, Timothy G. Constandinou, Nick Donaldson, Gavin J. Clowry, Nikhil K. Ponon, Andrew Jackson, Fiona E. N. LeBeau, Aaliyah Patel, Ahmad Shah Idil, Mark Turnbull, Carolina Gandara de Souza, Richard G. Bailey, Andrew J. Trevelyan, Anupam Hazra
Electrical neurostimulation is effective in treating neurological disorders, but associated recording artefacts generally limit applications to ‘open-loop’ stimuli. Since light does not prevent concurrent electrical recordings, optogenetics enabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61dcc05902cad0cc4f56c1f3995bb1e0
https://doi.org/10.21203/rs.3.rs-78230/v1
https://doi.org/10.21203/rs.3.rs-78230/v1
Autor:
Bernd Weber, Marcus Kaiser, Frances Hutchings, Christoforos A. Papasavvas, Emmanouil Giannakakis, Chencheng Zhang, Cheol E. Han
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0221380 (2020)
PLoS ONE
PLoS ONE
In patients with drug resistant focal epilepsy, targeted weak stimulation of the affected brain regions has been proposed as an alternative to surgery. However, the effectiveness of stimulation as a treatment presents great variation from patient to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a13af23fcf3fb201ed8e898ce18afd
Publikováno v:
Brain Stimulation, Vol 12, Iss 2, Pp 583-(2019)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53a6e0d13451f1f10c32b9e1628bd18
http://www.sciencedirect.com/science/article/pii/S1935861X1831355X
http://www.sciencedirect.com/science/article/pii/S1935861X1831355X
Publikováno v:
Scholarpedia. 15:53365
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0448cc08e7b24d249d7991d760aa624
https://doi.org/10.4249/scholarpedia.53365
https://doi.org/10.4249/scholarpedia.53365