Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Frances H. Stenhouse"'
Autor:
Kathy E O'Neill, Nicholas Bredenkamp, Christin Tischner, Harsh J Vaidya, Frances H Stenhouse, C Diana Peddie, Craig S Nowell, Terri Gaskell, C Clare Blackburn
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151666 (2016)
Thymus function requires extensive cross-talk between developing T-cells and the thymic epithelium, which consists of cortical and medullary TEC. The transcription factor FOXN1 is the master regulator of TEC differentiation and function, and declinin
Externí odkaz:
https://doaj.org/article/16c761d49bd44448a38f17c9ffa3a358
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114842 (2014)
Normal thymus function reflects interactions between developing T-cells and several thymic stroma cell types. Within the stroma, key functions reside in the distinct cortical and medullary thymic epithelial cell (TEC) types. It has been demonstrated
Externí odkaz:
https://doaj.org/article/64ff6000489f4cf9b1313ddfd4734f7c
Autor:
Frances H. Stenhouse, C. Clare Blackburn, David R. Withers, Monica Romera-Hernandez, Tom Cupedo, Janneke N. Samsom, C. Diana Peddie, Julien J. Karrich, Chelsea W. J. den Hollander, Remco Hoogenboezem, Patricia Aparicio-Domingo, Tanya Medley, Sharon Veenbergen, Ferry Cornelissen, Terri Gaskell, Louis Boon, Natalie Papazian
Publikováno v:
European Journal of Immunology
European Journal of Immunology, vol. 49, no. 2, pp. 290-301
European Journal of Immunology, 49(2), 290-301. Wiley-VCH
European Journal of Immunology, vol. 49, no. 2, pp. 290-301
European Journal of Immunology, 49(2), 290-301. Wiley-VCH
Under homeostatic conditions, dendritic cells (DCs) continuously patrol the intestinal lamina propria. Upon antigen encounter, DCs initiate C-C motif chemokine receptor 7 (CCR7) expression and migrate into lymph nodes to direct T cell activation and
Autor:
C. Diana Peddie, C. Clare Blackburn, Craig S. Nowell, Christin Tischner, Nicholas Bredenkamp, Frances H. Stenhouse, Terri Gaskell, Kathy E. O'Neill, Harsh J. Vaidya
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151666 (2016)
PLoS ONE
O'Neill, K E, Bredenkamp, N, Tischner, C, Vaidya, H J, Stenhouse, F H, Peddie, C D, Nowell, C S, Gaskell, T & Blackburn, C C 2016, ' Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution ', PLoS ONE, vol. 11, no. 3, pp. e0151666 . https://doi.org/10.1371/journal.pone.0151666
PLoS ONE
O'Neill, K E, Bredenkamp, N, Tischner, C, Vaidya, H J, Stenhouse, F H, Peddie, C D, Nowell, C S, Gaskell, T & Blackburn, C C 2016, ' Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution ', PLoS ONE, vol. 11, no. 3, pp. e0151666 . https://doi.org/10.1371/journal.pone.0151666
Thymus function requires extensive cross-talk between developing T-cells and the thymic epithelium, which consists of cortical and medullary TEC. The transcription factor FOXN1 is the master regulator of TEC differentiation and function, and declinin
Autor:
Grant Morahan, Frances H. Stenhouse, Simon R. Tomlinson, Kevin A. Robertson, Natalie F. Blair, Adelina Pagliocca, Alison Farley, Terri Gaskell, C. Clare Blackburn, Craig S. Nowell, Marianne G. L. Depreter, Kathleen Davern, Adrian Fraser, Jan Vrána
Publikováno v:
Depreter, M G L, Blair, N F, Gaskell, T L, Nowell, C S, Davern, K, Pagliocca, A, Stenhouse, F H, Farley, A M, Fraser, A, Vrana, J, Robertson, K, Morahan, G, Tomlinson, S R & Blackburn, C C 2008, ' Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells ', Proceedings of the National Academy of Sciences, vol. 105, no. 3, pp. 961–966 . https://doi.org/10.1073/pnas.0711170105
The thymus is essential for a functional immune system, because the thymic stroma uniquely supports T lymphocyte development. We have previously identified the epithelial progenitor population from which the thymus arises and demonstrated its ability
Autor:
Douglas Colby, Frances H. Stenhouse, Jennifer Nichols, Jamie R. K. Marland, Ian Chambers, Susan Tweedie, Morag Robertson
Publikováno v:
Mammalian Genome. 17:732-743
The Nanog gene plays a key role in the pluripotency of early embryonic cells in vitro and in vivo. In this article retrotransposed copies of Nanog, termed NanogPc and NanogPd, are identified on mouse Chromosomes 4 and 7, respectively. In contrast to
Autor:
Eric Vroegindeweij, C. Clare Blackburn, Frances H. Stenhouse, Lucy Morris, Harsh J. Vaidya, Marianne L G Depreter, Alison Farley, Richard A. Anderson, Jan J. Cornelissen, Simon R. Tomlinson, Tom Cupedo
Publikováno v:
Farley, A M, Morris, L X, Vroegindeweij, E, Depreter, M L G, Vaidya, H, Stenhouse, F H, Tomlinson, S R, Anderson, R A, Cupedo, T, Cornelissen, J J & Blackburn, C C 2013, ' Dynamics of thymus organogenesis and colonization in early human development ', Development, vol. 140, no. 9, pp. 2015-2026 . https://doi.org/10.1242/dev.087320
Development (Cambridge, England)
Development, 140(9), 2015-2026. Company of Biologists Ltd
Development (Cambridge, England)
Development, 140(9), 2015-2026. Company of Biologists Ltd
The thymus is the central site of T-cell development and thus is of fundamental importance to the immune system, but little information exists regarding molecular regulation of thymus development in humans. Here we demonstrate, via spatial and tempor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51113712341326b9a95ce66f16a0751
https://hdl.handle.net/20.500.11820/a6266cd9-f720-4a88-80be-b328d88a8316
https://hdl.handle.net/20.500.11820/a6266cd9-f720-4a88-80be-b328d88a8316
Autor:
Raphaela Heussen, Nicholas Bredenkamp, Xin Jin, Stéphanie Tetélin, Christin Tischner, Julie Sheridan, Harsh J. Vaidya, Craig S. Nowell, Frances H. Stenhouse, Andrew J.H. Smith, C. Clare Blackburn
Publikováno v:
Nowell, C S, Bredenkamp, N, Tetelin, S, Jin, X, Tischner, C, Vaidya, H, Sheridan, J M, Stenhouse, F H, Heussen, R, Smith, A J H & Blackburn, C C 2011, ' Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence ', PLoS Genetics, vol. 7, no. 11, e1002348, pp.-. https://doi.org/10.1371/journal.pgen.1002348
PLoS Genetics, Vol 7, Iss 11, p e1002348 (2011)
PLoS Genetics; Vol 7
PLoS Genetics
PLoS Genetics, Vol 7, Iss 11, p e1002348 (2011)
PLoS Genetics; Vol 7
PLoS Genetics
The forkhead transcription factor Foxn1 is indispensable for thymus development, but the mechanisms by which it mediates thymic epithelial cell (TEC) development are poorly understood. To examine the cellular and molecular basis of Foxn1 function, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e384b56093499033a839ef5667aeb2
https://www.pure.ed.ac.uk/ws/files/7514871/PLOS_2011_Blackburn.pdf
https://www.pure.ed.ac.uk/ws/files/7514871/PLOS_2011_Blackburn.pdf