The molecular epidemiology of the highly virulent ST93 Australian community Staphylococcus aureus strain.

Autor: Geoffrey W Coombs, Richard V Goering, Kyra Y L Chua, Stefan Monecke, Benjamin P Howden, Timothy P Stinear, Ralf Ehricht, Frances G O'Brien, Keryn J Christiansen

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43037 (2012)

In Australia the PVL-positive ST93-IV [2B], colloquially known as "Queensland CA-MRSA" has become the dominant CA-MRSA clone. First described in the early 2000s, ST93-IV [2B] is associated with skin and severe invasive infections including necrotizin

Externí odkaz: https://doaj.org/article/6e708f6520284c099e3b2d73eeeb0786

Methicillin-resistant Staphylococcus aureus Clones, Western Australia

Autor: Geoffrey W. Coombs, Julie C. Pearson, Frances G. O'Brien, Ronan J. Murray, Warren B. Grubb, Keryn J. Christiansen

Publikováno v: Emerging Infectious Diseases, Vol 12, Iss 2, Pp 241-247 (2006)

Community-associated methicillin-resistant Staphylococcus aureus (MRSA) was first reported in Western Australia in the early 1990s from indigenous peoples living in remote areas. Although a statewide policy of screening all hospital patients and staf

Externí odkaz: https://doaj.org/article/a319c99068b342abaca9d174daff8e31

Diversity of bacteriophages encoding Panton-Valentine leukocidin in temporally and geographically related Staphylococcus aureus

Autor: Sarah L. Baines, Geoffrey W. Coombs, Krister M. Swenson, Benjamin P Howden, Frances G. O'Brien

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2020, 15 (2), pp.e0228676. ⟨10.1371/journal.pone.0228676⟩
PLoS ONE, 2020, 15 (2), pp.e0228676. ⟨10.1371/journal.pone.0228676⟩
PLoS ONE, Vol 15, Iss 2, p e0228676 (2020)

Production of the Panton-Valentine leukocidin (PVL) by Staphylococcus aureus is mediated via the genes lukS-PV and lukF-PV which are carried on bacteriophage ϕSa2. PVL is associated with S. aureus strains that cause serious infections and clones of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afb80b125f8070ee18fdb6a52171f58
http://europepmc.org/articles/PMC7010278

Characterization of a novel staphylococcal cassette chromosome composite island from community-associated MRSA isolated in aged care facilities in Western Australia

Autor: Geoffrey W. Coombs, L. Wilson, Warren B. Grubb, Frances G. O'Brien, K. Christiansen

Publikováno v: Journal of Antimicrobial Chemotherapy. 71:3372-3375

Background: In Western Australia (WA), clonal complex 5, ST835, community-associated (CA) MRSA is isolated almost exclusively from aged care facilities. In WA four different staphylococcal cassette chromosome (SCC) mec (SCCmec) elements have been ide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c841a6f4eef59feedd6eb4d2f401a881
https://doi.org/10.1093/jac/dkw317

An updated view of plasmid conjugation and mobilization in Staphylococcus

Autor: Karina Yui Eto, Quang T. Nguyen, Warren B. Grubb, Neville Firth, Frances G. O'Brien, Joshua P. Ramsay, Riley J. T. Murphy, Geoffrey W. Coombs, Karina J. Price, Stephen M. Kwong

Publikováno v: Mobile Genetic Elements

The horizontal gene transfer facilitated by mobile genetic elements impacts almost all areas of bacterial evolution, including the accretion and dissemination of antimicrobial-resistance genes in the human and animal pathogen Staphylococcus aureus. G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bfd5149dfafe31105b2619f68cfd0a
https://pubmed.ncbi.nlm.nih.gov/27583185