Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Frances Fan"'
Autor:
Li Zhang, Lawrence Fong, Brittany Davidson, David Y Oh, Frances Fan, Alexander Cheung, Hai Yang, Jun Yan He, Yang-Joon Kim, Elvira Mennillo, Iulia Rusu, Jared Bain, Arjun A Rao, Christopher Andersen, Karen Law, Jessica Tsui, Alan Shen, Divyashree Kushnoor, Yimin Shi, Alexis J Combes, Angela O Pisco, Michael G Kattah
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Colitis caused by checkpoint inhibitors (CPI) is frequent and is treated with empiric steroids, but CPI colitis mechanisms in steroid-experienced or refractory disease are unclear.Methods Using colon biopsies and blood from predominantly s
Externí odkaz:
https://doaj.org/article/b3f6c1938ee54e789586fef9baa1e152
Autor:
Y. Jessica Huang, PhD, Vikren Sarkar, PhD, Adam Paxton, PhD, Hui Zhao, PhD, Frances Fan-Chi Su, PhD, Ryan Price, PhD, Bill J. Salter, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 7, Iss 1, Pp 100812- (2022)
Purpose: A modern radiation oncology electronic medical record (RO-EMR) system represents a sophisticated human-computer interface with the potential to reduce human driven errors and improve patient safety. As the RO-EMR becomes an integral part of
Externí odkaz:
https://doaj.org/article/a9662cd976104f499fb0050abc13b91d
Autor:
Kim Beasy, Mary Ann Hunter, David Hicks, Darren Pullen, Peter Brett, Damon Thomas, Robyn Reaburn, William Baker, Frances Fan, Vaughan Cruickshank, Elspeth Stephenson, Vesife Hatisaru
Publikováno v:
Journal of the Scholarship of Teaching and Learning, Vol 21, Iss 4 (2021)
In this essay, as a group of teacher educators, we discuss our experience of “walking the walk” of teacher education transformation at a time of urgent change. We reflect upon our process of integrating three key priorities in our preservice teac
Externí odkaz:
https://doaj.org/article/5b19b3c2f32c49c7b4aa846d75932689
Autor:
Fabrice Barlesi, Steven Kao, Philippe A Cassier, Hua Fang, Frances Fan, Kathryn Allaire, Shiming Ye, Debra T Chao, William R Henner, Joel S Hayflick, Michael A McDevitt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background CD40 agonist immunotherapy can potentially license antigen-presenting cells to promote antitumor T-cell activation and re-educate macrophages to destroy tumor stroma. Systemic administration of CD40 agonists has historically been associate
Externí odkaz:
https://doaj.org/article/20dbdf5be81c4b86b9fc3af9b764237c
Autor:
Lien Wang, Grace Lee, Amy Shih, Chester Kuei, Diane Nepomuceno, Michelle Wennerholm, Frances Fan, Jiejun Wu, Pascal Bonaventure, Timothy W. Lovenberg, Changlu Liu
Publikováno v:
Pharmacology Research & Perspectives, Vol 7, Iss 1, Pp n/a-n/a (2019)
Abstract GPR139 is a Gq‐coupled receptor activated by the essential amino acids L‐tryptophan (L‐Trp) and L‐phenylalanine (L‐Phe). We carried out mutagenesis studies of the human GPR139 receptor to identify the critical structural motifs req
Externí odkaz:
https://doaj.org/article/5ff1c31e50e9402583cdf92ec54b8a9d
Publikováno v:
Heliyon, Vol 5, Iss 2, Pp e01217- (2019)
Drosophila melanogaster is a powerful model to study mitochondrial respiratory chain defects, particularly succinate dehydrogenase (SDH) deficiency. Mutations in sdh genes cause degenerative disorders and often lead to death. Therapies for such patho
Externí odkaz:
https://doaj.org/article/5ad63311bc4e400e847bd9c679dbc140
Autor:
William R Henner, Kathryn Allaire, Michael A. McDevitt, Hua Fang, Karen Kelly, Shiming Ye, Hedy L. Kindler, Frances Fan, Ki Y. Chung, Steven Kao, Lawrence Fong, Jason J. Luke, Anthony W. Tolcher, Christophe Le Tourneau, Debra Chao, Maulik Patel, Mustafa Khasraw, Antoine Hollebecque, Philippe A. Cassier, Fabrice Barlesi, Joel S Hayflick, Vivek Subbiah, Frank Tsai
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundCD40 agonist immunotherapy can potentially license antigen-presenting cells to promote antitumor T-cell activation and re-educate macrophages to destroy tumor stroma. Systemic administration of CD40 agonists has historically been associated
Autor:
Jason Cham, Debrah Thompson, Alexander Cheung, James Cooley, Katsunobu Hagihara, Li Zhang, B.J. Kerns, Tao He, Hai Yang, Frances Fan, Lawrence Fong
Publikováno v:
Journal of immunological methods. 494
Neoadjuvant immunotherapy can induce immune responses within the tumor microenvironment. Gene expression can be used to assess responses with limited amounts of conventionally-fixed patient-derived samples. We aim to assess the cross-platform concord
Autor:
Lien Wang, Jiejun Wu, Amy Y. Shih, Chester Kuei, Pascal Bonaventure, Timothy W. Lovenberg, Diane Nepomuceno, Michelle Wennerholm, Grace Lee, Changlu Liu, Frances Fan
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 7, Iss 1, Pp n/a-n/a (2019)
Pharmacology Research & Perspectives, Vol 7, Iss 1, Pp n/a-n/a (2019)
GPR139 is a Gq‐coupled receptor activated by the essential amino acids L‐tryptophan (L‐Trp) and L‐phenylalanine (L‐Phe). We carried out mutagenesis studies of the human GPR139 receptor to identify the critical structural motifs required for
Autor:
Tolga Turan, Shiming Ye, Anita Reddy, Andrew Woolley, Joel S Hayflick, William R Henner, Debra Chao, Kathryn Allaire, Hua Fang, Cyril Ramathal, Michael A. McDevitt, Frances Fan, Lawrence Fong, Kinjal Hew
Publikováno v:
Cancer Research. 80:5672-5672
Background: ABBV-428 is a first-in-class bispecific antibody against CD40 and MSLN designed to stimulate CD40 for tumor-specific immune activation with limited systemic toxicity (Cancer Immunol Res 2019;7:1864). In phase I findings, ABBV-428 was well