Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Frances E. Pearson"'
Autor:
Ingrid M. Leal Rojas, Wai-Hong Mok, Frances E. Pearson, Yoshihito Minoda, Tony J. Kenna, Ross T. Barnard, Kristen J. Radford
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Dendritic cells (DC) initiate the differentiation of CD4+ helper T cells into effector cells including Th1 and Th17 responses that play an important role in inflammation and autoimmune disease pathogenesis. In mice, Th1 and Th17 responses are regulat
Externí odkaz:
https://doaj.org/article/368bcc3fe390459ea2023cb7accc203f
Autor:
Victoria Atkinson, Kelly-Anne Masterman, Ingrid M Leal-Rojas, Frances E Pearson, Kristen J Radford, Yoke Seng Lee, Liam J O'Brien, Carina M Walpole, Andrew Barbour
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background The conventional type 1 dendritic cell subset (cDC1) is indispensable for tumor immune responses and the efficacy of immune checkpoint inhibitor (ICI) therapies in animal models but little is known about the role of the human CD141+ DC cDC
Externí odkaz:
https://doaj.org/article/641ac534cc72482c8769def2a4229137
To Tweet or Not to Tweet: A Longitudinal Analysis of Social Media Use by Global Diabetes Researchers
Publikováno v:
Pharmaceutical Medicine
Background Engaging influential stakeholders in meaningful exchange is essential for pharmaceutical companies aiming to improve care. At a time where opportunities for face-to-face engagement are limited, the ability to interact, learn and generate a
Autor:
Carina Walpole, Ingrid M Leal-Rojas, Kelly-Anne Masterman, Liam O'Brien, Andrew Barbour, Kristen J. Radford, Yoke Seng Lee, Victoria Atkinson, Frances E. Pearson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
BackgroundThe conventional type 1 dendritic cell subset (cDC1) is indispensable for tumor immune responses and the efficacy of immune checkpoint inhibitor (ICI) therapies in animal models but little is known about the role of the human CD141+ DC cDC1
Autor:
Yoke Seng, Lee, Liam J, O'Brien, Carina M, Walpole, Frances E, Pearson, Ingrid M, Leal-Rojas, Kelly-Anne, Masterman, Victoria, Atkinson, Andrew, Barbour, Kristen J, Radford
Publikováno v:
Journal for Immunotherapy of Cancer
Background The conventional type 1 dendritic cell subset (cDC1) is indispensable for tumor immune responses and the efficacy of immune checkpoint inhibitor (ICI) therapies in animal models but little is known about the role of the human CD141+ DC cDC
Autor:
Frances E Pearson, Celia L McNeilly, Michael L Crichton, Clare A Primiero, Sally R Yukiko, Germain J P Fernando, Xianfeng Chen, Sarah C Gilbert, Adrian V S Hill, Mark A F Kendall
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67888 (2013)
The disadvantages of needle-based immunisation motivate the development of simple, low cost, needle-free alternatives. Vaccine delivery to cutaneous environments rich in specialised antigen-presenting cells using microprojection patches has practical
Externí odkaz:
https://doaj.org/article/939bada31aad4beab2f46dab10020487
Autor:
Frances E, Pearson, Kirsteen M, Tullett, Ingrid M, Leal-Rojas, Oscar L, Haigh, Kelly-Anne, Masterman, Carina, Walpole, John S, Bridgeman, James E, McLaren, Kristin, Ladell, Kelly, Miners, Sian, Llewellyn-Lacey, David A, Price, Antje, Tunger, Marc, Schmitz, John J, Miles, Mireille H, Lahoud, Kristen J, Radford
Publikováno v:
Clinical & Translational Immunology
Objectives Vaccines that prime Wilms' tumor 1 (WT1)‐specific CD8+ T cells are attractive cancer immunotherapies. However, immunogenicity and clinical response rates may be enhanced by delivering WT1 to CD141+ dendritic cells (DCs). The C‐type lec
Autor:
Antje Tunger, John S. Bridgeman, Ingrid M Leal-Rojas, David Price, Sian Llewellyn-Lacey, Frances E. Pearson, Marc Schmitz, Kelly-Anne Masterman, John J. Miles, Mireille H. Lahoud, Kelly L. Miners, Kristen J. Radford, Kirsteen M. Tullett, Carina Walpole, Oscar Haigh, James E. McLaren, Kristin Ladell
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 6, Pp n/a-n/a (2020)
Objectives\ud Vaccines that prime Wilms' tumor 1 (WT1)‐specific CD8+ T cells are attractive cancer immunotherapies. However, immunogenicity and clinical response rates may be enhanced by delivering WT1 to CD141+ dendritic cells (DCs). The C‐type
Autor:
Ghazal Daraj, Frances E. Pearson, Karshing Chang, Kristen J. Radford, Yoshihito Minoda, Kirsteen M. Tullett, Oscar Haigh, Ingrid M. Leal Rojas
Publikováno v:
Immunology and Cell Biology. 96:390-400
Mice reconstituted with human hematopoietic stem cells are valuable models to study aspects of the human immune system in vivo. We describe a humanized mouse model (hu mice) in which fully functional human CD141+ and CD1c+ myeloid and CD123+ plasmacy
Autor:
John B Carey, Frances E Pearson, Anto Vrdoljak, Marie G McGrath, Abina M Crean, Patrick T Walsh, Timothy Doody, Conor O'Mahony, Adrian V S Hill, Anne C Moore
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22442 (2011)
Vaccine delivery into the skin has received renewed interest due to ease of access to the immune system and microvasculature, however the stratum corneum (SC), must be breached for successful vaccination. This has been achieved by removing the SC by
Externí odkaz:
https://doaj.org/article/8b145e573f954fb79e3ec54b02b23df2