Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Frances E. Lund"'
Autor:
Miranda L. Curtiss, Alexander F. Rosenberg, Christopher D. Scharer, Betty Mousseau, Natalia A. Ballesteros Benavides, John E. Bradley, Beatriz León, Chad Steele, Troy D. Randall, Frances E. Lund
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionData from patient cohorts and mouse models of atopic dermatitis, food allergy and asthma strongly support a role for chitinase-3-like-1 protein (CHI3L1) in allergic disease.MethodsTo address whether Chi3l1 also contributes to TH2 response
Externí odkaz:
https://doaj.org/article/cac7025d889a467685c55cbc25d7bc30
Autor:
Michael D. Schultz, John J. Suschak, Davide Botta, Aaron Silva-Sanchez, R. Glenn King, Thomas W. Detchemendy, Chetan D. Meshram, Jeremy B. Foote, Fen Zhou, Jennifer L. Tipper, Jianfeng Zhang, Kevin S. Harrod, Sixto M. Leal, Troy D. Randall, M. Scot Roberts, Bertrand Georges, Frances E. Lund
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 6 (2022)
The coronavirus disease 2019 (COVID-19) pandemic has illustrated the critical need for effective prophylactic vaccination to prevent the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Intranasal vaccination is an attractive a
Externí odkaz:
https://doaj.org/article/bce98486f913451b8115f9d51ef70aaa
Autor:
Katie E. Heath, Joseph M. Feduska, Jared P. Taylor, Julie A. Houp, Davide Botta, Frances E. Lund, Gail J. Mick, Gerald McGwin, Kenneth L. McCormick, Hubert M. Tse
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1948 (2023)
Type 1 diabetes (T1D) is an autoimmune disease culminating in the destruction of insulin-producing pancreatic cells. There is a need for the development of novel antigen-specific strategies to delay cell destruction, including combinatorial strategie
Externí odkaz:
https://doaj.org/article/87fca8b0abb74ff7898353e973960d0c
Autor:
Michael D Schultz, Tulin Dadali, Sylvain A Jacques, Hélène Muller-Steffner, Jeremy B Foote, Leonardo Sorci, Esther Kellenberger, Davide Botta, Frances E Lund
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008539 (2020)
NAD, a key co-enzyme required for cell metabolism, is synthesized via two pathways in most organisms. Since schistosomes apparently lack enzymes required for de novo NAD biosynthesis, we evaluated whether these parasites, which infect >200 million pe
Externí odkaz:
https://doaj.org/article/38618719737b47b3b9c46e6de53e10de
Autor:
Doan C. Nguyen, Swetha Garimalla, Haopeng Xiao, Shuya Kyu, Igor Albizua, Jacques Galipeau, Kuang-Yueh Chiang, Edmund K. Waller, Ronghu Wu, Greg Gibson, James Roberson, Frances E. Lund, Troy D. Randall, Iñaki Sanz, F. Eun-Hyung Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Antibody-secreting cells (ASC) such as plasma cells must migrate to the bone marrow to survive, but microniche elements that promote survival are unknown. Here the authors define specific factors from the microniche that can maintain ASC in vitro for
Externí odkaz:
https://doaj.org/article/8d6c5b762cbe4e5192797c6d2043c3fe
Autor:
Sonia García-Rodríguez, Antonio Rosal-Vela, Davide Botta, Luz M. Cumba Garcia, Esther Zumaquero, Verónica Prados-Maniviesa, Daniela Cerezo-Wallis, Nicola Lo Buono, José-Ángel Robles-Guirado, Salvador Guerrero, Elena González-Paredes, Eduardo Andrés-León, Ángel Corbí, Matthias Mack, Friedrich Koch-Nolte, Ramón Merino, Mercedes Zubiaur, Frances E. Lund, Jaime Sancho
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Abstract In this study, we investigated the role of CD38 in a pristane-induced murine model of lupus. CD38-deficient (Cd38 −/−) but not ART2-deficient (Art2 −/−) mice developed less severe lupus compared to wild type (WT) mice, and their prot
Externí odkaz:
https://doaj.org/article/8fe211be315c44d088247d42cd122a41
Autor:
R. Glenn King, Aaron Silva-Sanchez, Jessica N. Peel, Davide Botta, Alexandria M. Dickson, Amelia K. Pinto, Selene Meza-Perez, S. Rameeza Allie, Michael D. Schultz, Mingyong Liu, John E. Bradley, Shihong Qiu, Guang Yang, Fen Zhou, Esther Zumaquero, Thomas S. Simpler, Betty Mousseau, John T. Killian, Brittany Dean, Qiao Shang, Jennifer L. Tipper, Christopher A. Risley, Kevin S. Harrod, Tsungwei Feng, Young Lee, Bethlehem Shiberu, Vyjayanthi Krishnan, Isabelle Peguillet, Jianfeng Zhang, Todd J. Green, Troy D. Randall, John J. Suschak, Bertrand Georges, James D. Brien, Frances E. Lund, M. Scot Roberts
Publikováno v:
Vaccines, Vol 9, Iss 8, p 881 (2021)
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the urgent need for effective prophylactic vaccination to prevent the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Intranasal vaccination is an attractive str
Externí odkaz:
https://doaj.org/article/2c3ec67e167b48a7a637b11e247315c6
Autor:
Tse, Katie E. Heath, Joseph M. Feduska, Jared P. Taylor, Julie A. Houp, Davide Botta, Frances E. Lund, Gail J. Mick, Gerald McGwin, Kenneth L. McCormick, Hubert M.
Publikováno v:
Biomedicines; Volume 11; Issue 7; Pages: 1948
Type 1 diabetes (T1D) is an autoimmune disease culminating in the destruction of insulin-producing pancreatic cells. There is a need for the development of novel antigen-specific strategies to delay cell destruction, including combinatorial strategie
Autor:
Esther Zumaquero, Sara L Stone, Christopher D Scharer, Scott A Jenks, Anoma Nellore, Betty Mousseau, Antonio Rosal-Vela, Davide Botta, John E Bradley, Wojciech Wojciechowski, Travis Ptacek, Maria I Danila, Jeffrey C Edberg, S Louis Bridges Jr, Robert P Kimberly, W Winn Chatham, Trenton R Schoeb, Alexander F Rosenberg, Jeremy M Boss, Ignacio Sanz, Frances E Lund
Publikováno v:
eLife, Vol 8 (2019)
Although B cells expressing the IFNγR or the IFNγ-inducible transcription factor T-bet promote autoimmunity in Systemic Lupus Erythematosus (SLE)-prone mouse models, the role for IFNγ signaling in human antibody responses is unknown. We show that
Externí odkaz:
https://doaj.org/article/fc145a6e8204428a8ea15655113e477f
Autor:
Saidulu Mattapally, Kevin M. Pawlik, Vladimir G. Fast, Esther Zumaquero, Frances E. Lund, Troy D. Randall, Tim M. Townes, Jianyi Zhang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 23 (2018)
Background We aim to generate a line of “universal donor” human induced pluripotent stem cells (hiPSCs) that are nonimmunogenic and, therefore, can be used to derive cell products suitable for allogeneic transplantation. Methods and Results hiPSC
Externí odkaz:
https://doaj.org/article/a327f67adb0a48f28f39de9cd732b010