Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Frances Davenport"'
Publikováno v:
Geophysical Research Letters. 49
Autor:
Mary Seeger, Christopher B. Eckman, Debra Yager, Michael K. Lee, Gopal Thinakaran, Steven G. Younkin, Neal G. Copeland, Grace Kim, Frances Davenport, Sangram S. Sisodia, Rong Wang, Sam Gandy, Hilda H. Slunt, Donald L. Price, Nancy A. Jenkins, Cristian Mihail Prada, Tamara Ratovitsky, Sophia Seekins, David R. Borchelt, Allan I. Levey
Publikováno v:
Neuron. 17(5):1005-1013
Mutations in the presenilin 1 (PS1) and presenilin 2 genes cosegregate with the majority of early-onset familial Alzheimer's disease (FAD) pedigrees. We now document that the Abeta1-42(43)/Abeta1-40 ratio in the conditioned media of independent N2a c
Autor:
Frances Davenport, Allan I. Levey, Sangram S. Sisodia, Sam Gandy, Mary Seeger, Tamara Ratovitsky, John Hardy, Christer Nordstedt, Lia Spitzer, Nancy A. Jenkins, Hilda H. Slunt, Donald L. Price, David R. Borchelt, Michael K. Lee, Neal G. Copeland, Gopal Thinakaran, Grace Kim
Publikováno v:
Neuron. 17:181-190
The majority of early-onset cases of familial Alzheimer's disease (FAD) are linked to mutations in two related genes, PS1 and PS2, located on chromosome 14 and 1, respectively. Using two highly specific antibodies against nonoverlapping epitopes of t