Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Frances Chow"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/3813d17967254296ba4480224b2ea549
Autor:
Gino K. In, Jennifer R. Ribeiro, Jun Yin, Joanne Xiu, Matias A. Bustos, Fumito Ito, Frances Chow, Gabriel Zada, Lindsay Hwang, April K. S. Salama, Soo J. Park, Justin C. Moser, Sourat Darabi, Evidio Domingo-Musibay, Maria L. Ascierto, Kim Margolin, Jose Lutzky, Geoffrey T. Gibney, Michael B. Atkins, Benjamin Izar, Dave S. B. Hoon, Ari M. VanderWalde
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Melanoma brain metastases (MBM) are clinically challenging to treat and exhibit variable responses to immune checkpoint therapies. Prior research suggests that MBM exhibit poor tumor immune responses and are enriched in oxidative phosphoryla
Externí odkaz:
https://doaj.org/article/32efd05519e741b4bbdba359b3adab39
Autor:
Alexander H. Lee, Lu Sun, Aaron Y. Mochizuki, Jeremy G. Reynoso, Joey Orpilla, Frances Chow, Jenny C. Kienzler, Richard G. Everson, David A. Nathanson, Steven J. Bensinger, Linda M. Liau, Timothy Cloughesy, Willy Hugo, Robert M. Prins
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Immune-checkpoint blockade has shown limited benefits in patients with glioblastoma. To understand how the composition of the tumor immune microenvironment might limit clinical responses, here the authors present a high dimensional profiling of the i
Externí odkaz:
https://doaj.org/article/bc4276916a1e42c19b71f6a03a3eba26
Autor:
Frances Chow, Michael Berens, Sharon Tamir, Yosef Landesman, Christopher Walker, Mark Krailo, Steven Gore, Jana Portnow
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 126-126 (2023)
OBJECTIVES/GOALS: Selinexor is a novel XPO1 inhibitor that blocks nuclear export, thus impairing DNA repair and causing apoptosis. Our goal was to conduct preclinical and clinical studies to test our hypothesis that selinexor’s efficacy is boosted
Externí odkaz:
https://doaj.org/article/3b387fb5faa140c6aeea72dc7a79b29e
Autor:
Dhiraj J Pangal, Benjamin Yarovinsky, Tyler Cardinal, David J Cote, Jacob Ruzevick, Frank J Attenello, Eric L Chang, Jason Ye, Josh Neman, Frances Chow, Gabriel Zada
Publikováno v:
Neuro-oncology advances. 4(1)
Background The abscopal effect is a rare phenomenon whereby local radiation induces a proposed immune-mediated anti-tumor effect at distant sites. Given the growing use of immunotherapies and systemic immune checkpoint inhibitors in neuro-oncologic p
Publikováno v:
Neuro-oncology advances. 4(1)
Glioblastoma (GBM) is the most common and aggressive primary adult brain tumor, with an estimated annual incidence of 17 000 new cases in the United States. Current treatments for GBM include chemotherapy, surgical resection, radiation therapy, and a
Autor:
Tulika Ranjan, Soma Sengupta, Michael J. Glantz, Richard M. Green, Alexander Yu, Dawit Aregawi, Rekha Chaudhary, Ricky Chen, Mario Zuccarello, Christine Lu-Emerson, Hugh D. Moulding, Neil Belman, Jon Glass, Aaron Mammoser, Mark Anderson, Jagan Valluri, Nicholas Marko, Jason Schroeder, Steven Jubelirer, Frances Chow, Pier Paolo Claudio, Anthony M. Alberico, Seth T. Lirette, Krista L. Denning, Candace M. Howard
Publikováno v:
Cell Reports Medicine. 4:101025
Autor:
Josh Neman, Behnaz Saatian, Krutika Deshpande, Vahan Martisorian, Peter LaViolette, Adrienne Boire, Frances Chow, Kyle Hurth, Peter Fecci, Mark Shiroishi, Rachel Eisenbarth
Publikováno v:
Neuro-Oncology. 24:vii21-vii22
Control of breast to brain metastasis remains an urgent unmet clinical need. While chemotherapies are essential in reducing systemic tumor burden, they have also shown to promote non-brain metastatic invasiveness and drug-driven neurocognitive defici
Autor:
Madison Shoaf, Frances Chow, Joanne Xiu, Michael Glantz, Sonikpreet Aulakh, David Ashley, Eric S Lipp, Giselle Lopez, Ashley Sumrall, Phillip Walker, David Spetzler, Theodore Nicolaides, Katherine B Peters
Publikováno v:
Neuro-Oncology. 24:vii154-vii155
INTRODUCTION Leptomeningeal disease (LMD) is a challenging complication of high grade glioma (HGG) and critical questions remain unanswered regarding clinicopathologic risk factors, molecular associations, and optimal treatment. METHODS Patients with
Autor:
Tulika Ranjan, Soma Sengupta, Michael Glantz, Richard Green, Alexander Yu, Dawit Aregawi, Rekha Chaudary, Ricky Chen, Mario Zuccarello, Christine Lu-Emerson, Hugh Moulding, Neil Belman, Jon Glass, Aaron Mammoser, Mark Anderson, Nicholas Marko, Jason Schroeder, Steven Jubelirer, Frances Chow, Anthony Alberico, Candace Howard, Seth Lirette, Krista Denning, Jagan Valluri, Pier Paolo Claudio
Publikováno v:
Neuro-Oncology. 24:vii73-vii74
The presence of therapy-resistant cancer stem cells (CSCs) in recurrent high-grade glioma (HGG) patients contributes to poor clinical outcomes. The ChemoID functional anti-cancer assay targets cancer stem cells along with the bulk of the tumor cells.