Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Frances Balkwill"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103102- (2024)
Summary: Studying cell behavior in live human tumors is crucial to understand and improve response to immunotherapies. Here, we present a protocol to slice human ovarian tumors ex vivo, maintain their viability for 24 h, and monitor the behavior of C
Externí odkaz:
https://doaj.org/article/2e2f2db53520410e94a0965c3780bbed
Autor:
Ivelina Tsocheva, James Scales, Rosamund Dove, Jasmine Chavda, Harpal Kalsi, Helen E Wood, Grainne Colligan, Louise Cross, Chris Newby, Amy Hall, Mia Keating, Luke Sartori, Jessica Moon, Ann Thomson, Florian Tomini, Aisling Murray, Wasim Hamad, Sarah Tijm, Alice Hirst, Britzer Paul Vincent, Pavani Kotala, Frances Balkwill, Borislava Mihaylova, Jonathan Grigg, Jennifer K Quint, Monica Fletcher, Mark Mon-Williams, John Wright, Esther van Sluijs, Sean Beevers, Gurch Randhawa, Sandra Eldridge, Aziz Sheikh, William Gauderman, Frank Kelly, Ian S Mudway, Christopher J Griffiths
Publikováno v:
BMC Pediatrics, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Air pollution harms health across the life course. Children are at particular risk of adverse effects during development, which may impact on health in later life. Interventions that improve air quality are urgently needed both to
Externí odkaz:
https://doaj.org/article/356c75d09bd64e84bc686934ad0b05d5
Autor:
Emine Ozturk, Mengya Zhao, Angelina Joy, Christina S. Marlow, Fidelia Law, Ashley R. Deutsch, Channing J. Mathews, Adam J. Hoffman, Luke McGuire, Mark Winterbottom, Frances Balkwill, Karen Burns, Laurence Butler, Marc Drews, Grace Fields, Hannah Smith, Adam Rutland, Adam Hartstone-Rose, Kelly Lynn Mulvey
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/e395eb93b12345338c5e6f7b014dc298
Autor:
Samuel G Smith, Samuel Smith, Robbie Foy, Andrew T Chan, Ruth Langley, Jack Cuzick, Mairead McKenzie, John Burn, Lucy Ziegler, Chris Hawkey, Colin Crooks, Paola Patrignani, Belinda Nedjai, Carlo Patrono, Mairead MacKenzie, Kelly E Lloyd, Sophie M C Green, Louise H Hall, David G Taylor, Frances Balkwill, Tim Bishop, Bianca Rocca, Laura Greaves
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Objectives Aspirin could be offered for colorectal cancer prevention for the UK general population. To ensure the views of the general population are considered in future guidance, we explored public perceptions of aspirin for preventive therapy.Desi
Externí odkaz:
https://doaj.org/article/20980d0cfa3d424d80c0ede8bfc55f25
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Recapitulating the normal physiology of the microvasculature is pivotal in the development of more complex in-vitro models and organ-on-chip designs. Pericytes are an important component of the vasculature, promoting vessel stability, inhibi
Externí odkaz:
https://doaj.org/article/f0fc5020034345f5bdddfcf09c87d820
Autor:
Florian Laforêts, Panoraia Kotantaki, Beatrice Malacrida, Samar Elorbany, Ranjit Manchanda, Emmanuel Donnadieu, Frances Balkwill
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106514- (2023)
Summary: Studies of the high-grade serous ovarian cancer (HGSOC) tumor microenvironment, the most lethal gynecological cancer, aim to enhance the efficiency of established therapies. Cell motility is an important process of anti-tumor response. Using
Externí odkaz:
https://doaj.org/article/4d987d96496c49cc950f690163d0635b
Autor:
Pedro Marques, Sayka Barry, Eivind Carlsen, David Collier, Amy Ronaldson, Sherine Awad, Neil Dorward, Joan Grieve, Nigel Mendoza, Samiul Muquit, Ashley B. Grossman, Frances Balkwill, Márta Korbonits
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-21 (2019)
Abstract Non-tumoural cells within the tumour microenvironment (TME) influence tumour proliferation, invasiveness and angiogenesis. Little is known about TME in pituitary neuroendocrine tumours (PitNETs). We aimed to characterise the role of TME in t
Externí odkaz:
https://doaj.org/article/a5db078b54424f31a5a19e3561c3c1a6
Autor:
Kelly Lynn Mulvey, Luke McGuire, Adam J Hoffman, Eric Goff, Adam Rutland, Mark Winterbottom, Frances Balkwill, Matthew J Irvin, Grace E Fields, Karen Burns, Marc Drews, Fidelia Law, Angelina Joy, Adam Hartstone-Rose
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236279 (2020)
This study explored topic interest, perceived learning and actual recall of exhibit content in 979 children and adolescents and 1,184 adults who visited informal science learning sites and interacted with an adult or youth educator or just the exhibi
Externí odkaz:
https://doaj.org/article/6186dc2c39644f1b9cf43d61fec1b029
Autor:
Frances Balkwill, Katie Chambers
Publikováno v:
PLoS Biology, Vol 13, Iss 9, p e1002240 (2015)
Centre of the Cell is a unique biomedical science education centre, a widening participation and outreach project in London's East End. This article describes Centre of the Cell's first five years of operation, the evolution of the project in respons
Externí odkaz:
https://doaj.org/article/c7c90bb8667c4d0aa76f13eb898a4234
Autor:
Melissa M. Phillips, Iuliia Pavlyk, Michael Allen, Essam Ghazaly, Rosalind Cutts, Josephine Carpentier, Joe Scott Berry, Callum Nattress, Shenghui Feng, Gunnel Hallden, Claude Chelala, John Bomalaski, Jeremy Steele, Michael Sheaff, Frances Balkwill, Peter W. Szlosarek
Publikováno v:
Pharmacological Reports. 75:570-584
Background Pegylated arginine deiminase (ADI-PEG20; pegargiminase) depletes arginine and improves survival outcomes for patients with argininosuccinate synthetase 1 (ASS1)-deficient malignant pleural mesothelioma (MPM). Optimisation of ADI-PEG20-base