Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Frances, Henson"'
Autor:
Ciara Whitty, Christian Pernstich, Charlotte Marris, Andrew McCaskie, Michael Jones, Frances Henson
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 4, Iss 1, Pp 100240- (2022)
Objective: Attempts to utilise growth factors (GF) such as bone morphogenic proteins (BMPs) to treat osteoarthritis (OA) in the clinic have not secured widespread adoption. However, the novel crystalline GF formulation called PODS offers new perspect
Externí odkaz:
https://doaj.org/article/712a594bd389472f8e8230903c42a495
Autor:
Hareklea Markides, Karin J. Newell, Heike Rudorf, Lia Blokpoel Ferreras, James E. Dixon, Robert H. Morris, Martin Graves, Joshua Kaggie, Frances Henson, Alicia J. El Haj
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-15 (2019)
Abstract Background Osteochondral injuries represent a significant clinical problem requiring novel cell-based therapies to restore function of the damaged joint with the use of mesenchymal stromal cells (MSCs) leading research efforts. Pre-clinical
Externí odkaz:
https://doaj.org/article/bba3269c1a2447eda8b27fd171cd7cd9
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Damage to joints through injury or disease can result in cartilage loss, which if left untreated can lead to inflammation and ultimately osteoarthritis. There is currently no cure for osteoarthritis and management focusses on symptom control. End-sta
Externí odkaz:
https://doaj.org/article/97d4cade17784df8b8ebdc10d0ef0d19
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-6 (2018)
Abstract Background Recent research has demonstrated that circulating peripheral blood mononuclear fractions (PBMC) containing haematopoietic stem (HSC)/progenitor cells have the potential to play a crucial role in regenerative medicine strategies. W
Externí odkaz:
https://doaj.org/article/d8194d28ac15408daf7187309ac4fdcd
Autor:
Lucy F Donaldson, Ramiro Alberio, Jennifer Batson, Frances Henson, Roger Lemon, Anna Mitchell, Jo Murrell, Domingo Tortonese
Publikováno v:
Physiology News. :18-22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e19e59970afeba07e216cddea3c728d0
https://doi.org/10.36866/pn.124.18
https://doi.org/10.36866/pn.124.18
Autor:
Anne Gigout, Daniela Werkmann, Stephanie Menges, Christian Brenneis, Frances Henson, Kyra J. Cowan, Djordje Musil, Christian S. Thudium, Hans Gühring, Martin Michaelis, Kerstin Kleinschmidt‐Doerr
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.)REFERENCES.
To preclinically characterize a mutant form of growth and differentiation factor 5, R399E, with reduced osteogenic properties as a potential disease-modifying osteoarthritis (OA) drug.Cartilage, synovium, and meniscus samples from patients with OA we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd67f19e8ce2e025bc961c0a7fd27ee
https://pubmed.ncbi.nlm.nih.gov/36054172
https://pubmed.ncbi.nlm.nih.gov/36054172
Autor:
Frances Henson
Publikováno v:
UK-Vet Equine. 4:112-115
Primary or secondary back pain is commonly diagnosed in horses, however it can be difficult to establish the exact cause and to recommend the correct treatment. This article provides a framework for investigation of possible back pain with the aims o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f2c77b963ef5a357e33a5b7628132b0
https://doi.org/10.12968/ukve.2020.4.4.112
https://doi.org/10.12968/ukve.2020.4.4.112
Publikováno v:
Stem Cells International, Vol 2015 (2015)
A major challenge in cartilage repair is the lack of chondrogenic cells migrating from healthy tissue into damaged areas and strategies to promote this should be developed. The aim of this study was to evaluate the effect of peripheral blood derived
Externí odkaz:
https://doaj.org/article/fce6ed4e32c347d88a3aed1334db0bb1
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133937 (2015)
This study characterized peripheral blood mononuclear cells (PBMC) in terms of their potential in cartilage repair and investigated their ability to improve the healing in a pre-clinical large animal model. Human PBMCs were isolated with gradient cen
Externí odkaz:
https://doaj.org/article/8cca4859ee4b4c388160dec42ec55cb8
Autor:
Sampurna Chakrabarti, Minji Ai, Wai Ying Katherine Wong, Frances Henson, Ewan St. John Smith, Karin Newell
Publikováno v:
eNeuro
Knee joint trauma can cause an osteochondral defect (OD), a risk factor for osteoarthritis and cause of debilitating pain in patients. Rodent OD models are less translatable due to their smaller joint size and open growth plate. This study proposes s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d7094af547178f6896754968c62a82
http://edoc.mdc-berlin.de/21010/7/21010suppl.tif
http://edoc.mdc-berlin.de/21010/7/21010suppl.tif
