Zobrazeno 1 - 10
of 33
pro vyhledávání: '"France Bourdeau"'
Tumour extracellular vesicles induce neutrophil extracellular traps to promote lymph node metastasis
Autor:
Xin Su, Ariane Brassard, Alexandra Bartolomucci, Iqraa Dhoparee‐Doomah, Qian Qiu, Thupten Tsering, Ramin Rohanizadeh, Olivia Koufos, Betty Giannias, France Bourdeau, Lixuan Feng, Julia Messina‐Pacheco, Sabrina Leo, Veena Sangwan, Daniela Quail, James Tankel, Jonathan Spicer, Julia Valdemarin Burnier, Swneke Donovan Bailey, Lorenzo Ferri, Jonathan Cools‐Lartigue
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 8, Pp n/a-n/a (2023)
Abstract Lymph nodes (LNs) are frequently the first sites of metastasis. Currently, the only prognostic LN assessment is determining metastatic status. However, there is evidence suggesting that LN metastasis is facilitated by the formation of a pre
Externí odkaz:
https://doaj.org/article/b0f4fcc5c4344adf8ccdea71e65e11c9
Autor:
Surashri Shinde-Jadhav, Jose Joao Mansure, Roni F. Rayes, Gautier Marcq, Mina Ayoub, Rodrigo Skowronski, Ronald Kool, France Bourdeau, Fadi Brimo, Jonathan Spicer, Wassim Kassouf
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Radioresistance remains a challenge in the treatment of bladder cancer. In this study, the authors show in mice that radiation increases deposits of neutrophil extracellular traps (NETs) via a TLR4-dependent mechanism and that NETs-targeting strategi
Externí odkaz:
https://doaj.org/article/8c246e604f66445097df274b8e85bffd
Autor:
Henry Y. Jiang, Sara Najmeh, Guy Martel, Elyse MacFadden-Murphy, Raquel Farias, Paul Savage, Arielle Leone, Lucie Roussel, Jonathan Cools-Lartigue, Stephen Gowing, Julie Berube, Betty Giannias, France Bourdeau, Carlos H. F. Chan, Jonathan D. Spicer, Rebecca McClure, Morag Park, Simon Rousseau, Lorenzo E. Ferri
Publikováno v:
Protein & Cell, Vol 11, Iss 3, Pp 187-201 (2020)
Abstract While emerging data suggest nucleotide oligomerization domain receptor 1 (NOD1), a cytoplasmic pattern recognition receptor, may play an important and complementary role in the immune response to bacterial infection, its role in cancer metas
Externí odkaz:
https://doaj.org/article/541092789c6343c9b39f754dcedac5c4
Soluble factors in malignant ascites promote the metastatic adhesion of gastric adenocarcinoma cells
Autor:
Luai Al-Marzouki, Vivian S. Stavrakos, Sanjima Pal, Betty Giannias, France Bourdeau, Roni Rayes, Nicholas Bertos, Sara Najmeh, Jonathan D. Spicer, Jonathan Cools-Lartigue, Swneke D. Bailey, Lorenzo Ferri, Veena Sangwan
Publikováno v:
Gastric Cancer. 26:55-68
Adenocarcinoma of the proximal stomach is the fastest rising malignancy in North America. It is commonly associated with peritoneal accumulation of malignant ascites (MA), a fluid containing cancer and inflammatory cells and soluble proteins. Periton
Autor:
Pnina Brodt, Zu-Hua Gao, Maximilien Evrard, Ben Vainer, Gunilla Høyer-Hansen, Rikke Loevendahl Eefsen, Martin Illemann, Patrick Auguste, France Bourdeau, Maria Celia Fernandez, Zarina D'Costa, Ni Wang, Boram Ham
Supplementary Table 1. List of antibodies and conditions. Supplementary Table 2. List of qPCR primers. Supplementary Table 3. Oligonucleotide sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3888ad4435c9024d2983ec2bc73eff3f
https://doi.org/10.1158/0008-5472.22406864
https://doi.org/10.1158/0008-5472.22406864
Autor:
Pnina Brodt, Zu-Hua Gao, Maximilien Evrard, Ben Vainer, Gunilla Høyer-Hansen, Rikke Loevendahl Eefsen, Martin Illemann, Patrick Auguste, France Bourdeau, Maria Celia Fernandez, Zarina D'Costa, Ni Wang, Boram Ham
Legends for 8 supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24afa4c3d327602fd664baaa29187d4b
https://doi.org/10.1158/0008-5472.22406870
https://doi.org/10.1158/0008-5472.22406870
Autor:
Pnina Brodt, Zu-Hua Gao, Maximilien Evrard, Ben Vainer, Gunilla Høyer-Hansen, Rikke Loevendahl Eefsen, Martin Illemann, Patrick Auguste, France Bourdeau, Maria Celia Fernandez, Zarina D'Costa, Ni Wang, Boram Ham
Supplementary Fig 1. Identification of hepatic cells that express TNFR2. Supplementary Fig 2. Loss of TNFR2 expression does not affect the induction of CAM expression on LSEC. Supplementary Fig 3. Additional characterization of MDSC isolated from wil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7587481ca16db88c0fc7e8c1ece277d5
https://doi.org/10.1158/0008-5472.22406867
https://doi.org/10.1158/0008-5472.22406867
Autor:
Ariane Brassard, Xin Su, Iqraa Dhoparee-Doomah, Sabrina Leo, Lixuan Feng, France Bourdeau, Betty Giannias, Corissa Larson, Qian Qiu, Jonathan Spicer, Lorenzo Ferri, Jonathan Cools-Lartigue
Publikováno v:
Cancer Research. 83:1315-1315
Metastasis is responsible for 90% of all cancer-related deaths, making it the most significant challenge in cancer treatment for clinicians worldwide. Metastasis is thought to occur in a stepwise process, in which local lymph nodes (LNs) are first co
Autor:
Xin SU, Ariane Brassard, Iqraa Dhoparee-Doomah, Ramin Rohanizadeh, Betty Giannias, France Bourdeau, Veena Sangwan, Roni Rayes, Jonathan Spicer, Lorenzo Ferri, Jonathan Cools-Lartigue
Publikováno v:
Journal of Clinical Oncology. 40:4033-4033
4033 Background: In most human cancers, regional lymph nodes (LNs) are the first sites of metastasis. In addition to being an important part of the tumor staging system, with the advent of novel therapies, lymph node metastasis has become a crucial c
Autor:
Veena, Sangwan, Luai, Al-Marzouki, Sanjima, Pal, Vivian, Stavrakos, Malak, Alzahrani, Dorothy, Antonatos, Yehonatan, Nevo, Sophie, Camilleri-Broët, Roni, Rayes, France, Bourdeau, Betty, Giannias, Nicholas, Bertos, Swneke, Bailey, Simon, Rousseau, Jonathan, Cools-Lartigue, Jonathan D, Spicer, Lorenzo, Ferri
Publikováno v:
Clinicalexperimental metastasis. 39(2)
Surgical resection, the cornerstone of curative intent treatment for gastric adenocarcinoma, is associated with a high rate of infection-related post-operative complications, leading to an increased incidence of metastasis to the peritoneum. However,