Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Francarosa Baccichetti"'
Publikováno v:
Arzneimittelforschung. 56:707-713
1,4,6,8-Tetramethyl-2H-furo[2,3-h]quinolin-2-one (FQ) belongs to a series of furocoumarin isosters, designed to obtain new drugs for photochemotherapy. The objective of this study was to characterize the disposition of orally administered 3 H-FQ in n
Publikováno v:
Bioorganic & Medicinal Chemistry. 11:1311-1318
4-Hydroxymethyl-1,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one (HOFQ) was prepared by a new profitable way, which allowed to synthesize also 4-methoxymethyl-1,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one (MOFQ), and 4-hydroxymethyl-6,8-dimethylfuro[2,3-h
Autor:
Francarosa Baccichetti, Cristina Marzano, Maria Grazia Ferlin, Gianfranco Chiarelotto, Franco Bordin
Publikováno v:
European Journal of Medicinal Chemistry. 35:827-837
A group of 9-substituted acridine and azacridine derivatives (m-AMSA analogues) were synthesised following classical procedures as potential antitumour agents with inhibitory effects on DNA topoisomerase II. Some were found to have noticeable cytotox
Autor:
B. Pani, Francarosa Baccichetti, Paolo Rodighiero, Elio Russo, Franco Bordin, Christine Marzano, Barbisin M, F. Carlassare, M. Tamaro
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 311:277-285
The ability of 4-hydroxymethyl-4',5'-benzopsoralen (HMBP) to damage DNA of Chinese hamster ovary cells (CHO) and to inhibit the activity of topoisomerase II in vitro has been studied. This compound is characterized by a fourth ring condensed at the f
Autor:
Paolo Rodighiero, C. Gatto, Francarosa Baccichetti, Christine Marzano, F. Carlassare, Franco Bordin
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 26:197-201
4,6,4′-Trimethylangelicin, a well-known effective photosensitizer described as a pure monofunctional reactant with DNA, can induce interstrand cross-links in mammalian cell DNA in vivo (about 15% relative to 8-methoxypsoralen), as observed using al
Autor:
Francarosa Baccichetti, Christine Marzano, Franco Bordin, Adriana Chilin, Paolo Rodighiero, F. Carlassare, Andrea Guiotto
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 24:101-108
Some photobiological properties of 2,6-dimethyl-9-methoxy-4H-pyrrolo [3,2,1-ij]quinolin-4-one (PQ) have been studied in comparison with 8-methoxypsoralen (8-MOP). In Ehrlich cells, PQ induced a moderate inhibition in DNA and RNA syntheses in the dark
Autor:
Guendalina Trovóa, Andrea Tapparo, Franco Bordin, Bruno Longato, A. Furlani, Manlio Palumbo, Francarosa Baccichetti, Vito Scarcia, Benedetto Corain
Publikováno v:
J. Chem. Soc., Dalton Trans.. :1547-1550
The solvolytic behaviour of the complex cis-[Pt(PMe3)2Cl2] was investigated in water and dimethyl sulfoxide. Mono-and bis-solvento species have been characterized mainly by 31P NMR spectroscopy. The water-soluble species cis-[{Pt(PMe3)2(µ-OH)}2]2+,
Autor:
Gianfranco Chiarelotto, Francarosa Baccichetti, F. Carlassare, Christine Marzano, Maria Grazia Ferlin, S. Mobilio
Publikováno v:
ChemInform. 26
Autor:
Brunella Piucci, Giuseppe Falcone, Giulia Menozzi, Luisa Mosti, Walter Filippelli, Francarosa Baccichetti, Christine Marzano, Eleonora Lo Presti
Publikováno v:
ChemInform. 30
A series of angelicin heteroanalogues, in which the furan was replaced by thiophene or a 1-substituted pyrazole moiety, was synthesised in order to obtain potential therapeutic agents with antiproliferative and/or other biological activities. In gene
Autor:
Franca Majone, Adriano Guiotto, Franco Bordin, Francarosa Baccichetti, A Capozzi, Maria Teresa Conconi, F. Carlassare
Publikováno v:
Photochemistry and Photobiology. 55:221-229
The biological activity of some benzopsoralen derivatives, prepared with the aim of obtaining new drugs for photochemotherapy, has been studied. The more interesting compounds are 4-hydroxymethyl-4',5'-benzopsoralen and 4-hydroxymethyl-4',5'-tetrahyd