Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Franca Ligas"'
Publikováno v:
EJC Paediatric Oncology, Vol 4, Iss , Pp 100190- (2024)
Background: Despite the positive changes brought by the Paediatric Regulation in the European Union (EU) in 2007, drug development in children remains challenging. Methods: To better understand the issues encountered to reach an authorisation for pae
Externí odkaz:
https://doaj.org/article/819fee0dfd0f437482c926e7ecb5a6c8
Autor:
Andrew DJ. Pearson, Carl Allen, Jason Fangusaro, Caroline Hutter, Olaf Witt, Susan Weiner, Gregory Reaman, Mark Russo, Pratiti Bandopadhayay, Sama Ahsan, Amy Barone, Elly Barry, Teresa de Rojas, Michael Fisher, Elizabeth Fox, Julia Glade Bender, Lia Gore, Darren Hargrave, Doug Hawkins, Brent Kreider, Abraham J. Langseth, Giovanni Lesa, Franca Ligas, Marcelo Marotti, Lynley V. Marshall, Kahina Nasri, Koen Norga, Karsten Nysom, Alberto Pappo, Gianluca Rossato, Nicole Scobie, Malcolm Smith, Elliot Stieglitz, Brenda Weigel, Amy Weinstein, Ruth Viana, Dominik Karres, Gilles Vassal
Publikováno v:
European Journal of Cancer. 177:120-142
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e51cb81f4e064a01a1e1d2c5bc7d4f56
https://doi.org/10.1016/j.ejca.2022.09.036
https://doi.org/10.1016/j.ejca.2022.09.036
Autor:
Dominik Karres, Giovanni Lesa, Franca Ligas, Sylvie Benchetrit, Sara Galluzzo, Karen Van Malderen, Jaroslav Sterba, Maaike van Dartel, Marleen Renard, Peter Sisovsky, Siri Wang, Koen Norga
Publikováno v:
European journal of cancer
Introduction: Regulatory decisions on paediatric investigation plans (PIPs) aim at making effective and safe medicines timely available for children with high unmet medical need. At the same time, scientific knowledge progresses continuously leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3a09b8c0e9db5040e90cfbb20da6d1
https://doi.org/10.1016/j.ejca.2022.09.025
https://doi.org/10.1016/j.ejca.2022.09.025
Autor:
Elizabeth Fox, Michael Berntgen, Alfonso Quintás-Cardama, Veronique Minard-Colin, Susan L. Weiner, André Baruchel, Laura Pearce, Karsten Nysom, Andrew D.J. Pearson, Danielle H. Taylor, Christian M. Zwaan, Nirali N. Shah, Yousif Matloub, Ivan D. Horak, Gregory H. Reaman, Gilles Vassal, Koen Norga, Claudia Rossig, Dominik Karres, Lori A. Ehrlich, Martina Schüßler-Lenz, Alberto S. Pappo, Joe McDonough, Martina A. Sersch, Nick Richardson, Donna Ludwinski, Abraham Bassan, Eric Bleickardt, Nicole Scobie, Stephen Gottschalk, Rob Pieters, Sarah K. Tasian, Courtney Johnson, Teresa de Rojas, Malcolm A. Smith, Franca Ligas, Lynley V. Marshall, Shannon L. Maude, Brenda J. Weigel, Nick Bird, Najat Bouchkouj, Behzad K. Masouleh, Sarah Beaussant Cohen, Delphine Heenen, Rosanna Ricafort, G. Lesa, Linda Hanssens, Peter F. Bross, Carrie Brownstein, Crystal L. Mackall, Martin Pule, Douglas S. Hawkins, Jaroslav Sterba, Maksim Mamonkin
Publikováno v:
European Journal of Cancer. 160:112-133
The seventh multi-stakeholder Paediatric Strategy Forum focused on chimeric antigen receptor (CAR) T-cells for children and adolescents with cancer. The development of CAR T-cells for patients with haematological malignancies, especially B-cell precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::109dc83dd17c2fd2077a3e812e4df67f
https://doi.org/10.1016/j.ejca.2021.10.016
https://doi.org/10.1016/j.ejca.2021.10.016
Autor:
Lynley V. Marshall, Brenda J. Weigel, G. Lesa, Joe McDonough, Malcolm A. Smith, Gudrun Schleiermacher, Nick Bird, Franca Ligas, Elly Barry, Yael P. Mosse, D Valteau, Eric J. Lowe, Nicholas Richardson, François Doz, Meredith S. Irwin, Zachary Franklin Zimmerman, Toby Trahair, Koen Norga, Sonia Singh, Martha Donoghue, Steven G. DuBois, Susan L. Weiner, Michela Casanova, Giovanni Selvaggi, Andrew D.J. Pearson, Dominik Karres, Yousif Matloub, Keith D. Wilner, Teresa de Rojas, Nicole Scobie, Rajkumar Venkatramani, Gilles Vassal, H.N. Caron, Amar Gajjar, Amy Barone, Patricia Blanc, Margret Merino, Diana Bradford, Gregory H. Reaman, Willi Woessmann, Elizabeth Fox, Vickie Buenger, Julie Park, Karsten Nysom
Publikováno v:
European Journal of Cancer. 157:198-213
The first (2017) and sixth (2021) multistakeholder Paediatric Strategy Forums focused on anaplastic lymphoma kinase (ALK) inhibition in paediatric malignancies. ALK is an important oncogene and target in several paediatric tumours (anaplastic large c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20a27456377fec5606ed5dc5201b2b93
https://doi.org/10.1016/j.ejca.2021.08.022
https://doi.org/10.1016/j.ejca.2021.08.022
Autor:
Andrew D J Pearson, Teresa de Rojas, Dominik Karres, Gregory Reaman, Nicole Scobie, Elizabeth Fox, Giovanni Lesa, Franca Ligas, Koen Norga, Karsten Nysom, Alberto Pappo, Brenda Weigel, Susan Weiner, Gilles Vassal
Publikováno v:
The lancet oncology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9231f88dde93b52f04d199665343f5ba
https://pubmed.ncbi.nlm.nih.gov/36328007
https://pubmed.ncbi.nlm.nih.gov/36328007
Autor:
Joe McDonough, G. Lesa, Franca Ligas, Miguel Rivera, Ira Jacobs, Andrew D.J. Pearson, Malcolm A. Smith, Maureen Hattersley, Dominik Karres, Aundrietta D. Duncan, Nada Jabado, Daniel D. De Carvalho, Koen Norga, Peter C. Adamson, Donna Ludwinski, Gregory H. Reaman, Brian Gadbaw, Elizabeth Fox, Samuel C. Blackman, Mark W. Kieran, Gilles Vassal, Christian Baumann, Vickie Buenger, Delphine Heenen, Scott A. Armstrong, Michael J. Kelly, Amy Barone, Adrian Senderowicz, Franck Bourdeaut, Martha Donoghue, Tilmann Taube, Peter T.C. Ho, Lynley V. Marshall, Patrick A. Brown, Michael L. Meyers, Kimberly Stegmaier, Zariana Nikolova, Susan L. Weiner
Publikováno v:
European Journal of Cancer. 139:135-148
The fifth multistakeholder Paediatric Strategy Forum focussed on epigenetic modifier therapies for children and adolescents with cancer. As most mutations in paediatric malignancies influence chromatin-associated proteins or transcription and paediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c517dea500b05206723e5227a0df2155
https://doi.org/10.1016/j.ejca.2020.08.014
https://doi.org/10.1016/j.ejca.2020.08.014
Autor:
Elly Barry, Gilles Vassal, Thomas Winkler, Gregory H. Reaman, Kerri Nottage, Anne Borgman, Florence Binlich, Dirk Reinhardt, Jan-Henning Klusmann, Delphine Heenen, C. Michel Zwaan, Silvia Mappa, Bouchra Benettaib, Koen Norga, Su Young Kim, Gertjan J.L. Kaspers, Malcolm A. Smith, Peter C. Adamson, Renaud Capdeville, Lynley V. Marshall, Linda Fogelstrand, David Delgado, Mark W. Kieran, Sarah K. Tasian, E. Anders Kolb, Julie Guillot, Paula Goodman Fraenkel, Hesham Mohamed, G. Lesa, Henrik Hasle, Andrew D.J. Pearson, Franca Ligas, J. Morris, Stephen J. Simko, Todd M. Cooper, Dominik Karres, Erica Brivio, Andrew S. Moore, Douglas V. Faller, Nicole Scobie
Publikováno v:
European journal of cancer (Oxford, England : 1990)
European Journal of Cancer
European Journal of Cancer
Purpose: The current standard-of-care for front-line therapy for acute myeloid leukaemia (AML) results in short-term and long-term toxicity, but still approximately 40% of children relapse. Therefore, there is a major need to accelerate the evaluatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a151be0d38eb16c4837f136811936399
https://doi.org/10.1016/j.ejca.2020.04.038
https://doi.org/10.1016/j.ejca.2020.04.038
Autor:
Andrew Dj, Pearson, Claudia, Rossig, Crystal, Mackall, Nirali N, Shah, Andre, Baruchel, Gregory, Reaman, Rosanna, Ricafort, Delphine, Heenen, Abraham, Bassan, Michael, Berntgen, Nick, Bird, Eric, Bleickardt, Najat, Bouchkouj, Peter, Bross, Carrie, Brownstein, Sarah Beaussant, Cohen, Teresa, de Rojas, Lori, Ehrlich, Elizabeth, Fox, Stephen, Gottschalk, Linda, Hanssens, Douglas S, Hawkins, Ivan D, Horak, Danielle H, Taylor, Courtney, Johnson, Dominik, Karres, Franca, Ligas, Donna, Ludwinski, Maksim, Mamonkin, Lynley, Marshall, Behzad K, Masouleh, Yousif, Matloub, Shannon, Maude, Joe, McDonough, Veronique, Minard-Colin, Koen, Norga, Karsten, Nysom, Alberto, Pappo, Laura, Pearce, Rob, Pieters, Martin, Pule, Alfonso, Quintás-Cardama, Nick, Richardson, Martina, Schüßler-Lenz, Nicole, Scobie, Martina A, Sersch, Malcolm A, Smith, Jaroslav, Sterba, Sarah K, Tasian, Brenda, Weigel, Susan L, Weiner, Christian Michel, Zwaan, Giovanni, Lesa, Gilles, Vassal
Publikováno v:
European journal of cancer
European journal of cancer, 160:112-133
European journal of cancer, 160:112-133
The seventh multi-stakeholder Paediatric Strategy Forum focused on chimeric antigen receptor (CAR) T-cells for children and adolescents with cancer. The development of CAR T-cells for patients with haematological malignancies, especially B-cell precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7e4b2ff665e9b497893f3198ef4554c2
https://repository.uantwerpen.be/docstore/d:irua:12922
https://repository.uantwerpen.be/docstore/d:irua:12922
Autor:
Sofia Nordenmalm, Franca Ligas, Joana Claverol, Ann Marie Tötterman, Benjamin Pelle, Begonya Nafria, Birka Lehmann, Elin Kimland
Publikováno v:
Archives of Disease in Childhood. 104:900-905
IntroductionLimited information is available on the views of children taking medicines and participating in clinical trials. These views may contribute to a better understanding of what can be improved on in the development of medicines from their pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e960e362c06b99d5a28cb1cd24087a5
https://doi.org/10.1136/archdischild-2018-316511
https://doi.org/10.1136/archdischild-2018-316511