Zobrazeno 1 - 10
of 26
pro vyhledávání: '"François Liger"'
Autor:
Chloé Laurencin, Sophie Lancelot, Florent Gobert, Jérôme Redouté, Inés Mérida, Thibault Iecker, François Liger, Zacharie Irace, Elise Greusard, Ludovic Lamberet, Didier Le Bars, Nicolas Costes, Bénédicte Ballanger
Publikováno v:
NeuroImage, Vol 240, Iss , Pp 118328- (2021)
Previous work introduced the [11C]yohimbine as a suitable ligand of central α2-adrenoreceptors (α2-ARs) for PET imaging. However, reproducibility of [11C]yohimbine PET measurements in healthy humans estimated with a simplified modeling method with
Externí odkaz:
https://doaj.org/article/aeed9e2b59214cd7986caf3c44974412
Autor:
Laurent Meijer, Vicente Notario, Jane A. Endicott, Aude Echalier, Benoît Joseph, Bernard Marquet, François Liger, Michael H.G. Kubbutat, Christoph Schächtele, Peter Drueckes, Silvia Mateo-Lozano, Jonathan C. Morris, Olivier Lozach, Yoan Ferandin, Séverine Marionneau-Lambot, Oscar M. Tirado, Karima Bettayeb
Protein kinases represent promising anticancer drug targets. We describe here the meriolins, a new family of inhibitors of cyclin-dependent kinases (CDK). Meriolins represent a chemical structural hybrid between meridianins and variolins, two familie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862a2f4d144630c783bf14488d81f62d
https://doi.org/10.1158/0008-5472.c.6495774.v1
https://doi.org/10.1158/0008-5472.c.6495774.v1
Autor:
Laurent Meijer, Vicente Notario, Jane A. Endicott, Aude Echalier, Benoît Joseph, Bernard Marquet, François Liger, Michael H.G. Kubbutat, Christoph Schächtele, Peter Drueckes, Silvia Mateo-Lozano, Jonathan C. Morris, Olivier Lozach, Yoan Ferandin, Séverine Marionneau-Lambot, Oscar M. Tirado, Karima Bettayeb
Supplementary Figure 4 from Meriolins, a New Class of Cell Death–Inducing Kinase Inhibitors with Enhanced Selectivity for Cyclin-Dependent Kinases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3970f1381a1112fc3eac3f8d94c493
https://doi.org/10.1158/0008-5472.22368006
https://doi.org/10.1158/0008-5472.22368006
Autor:
Laurent Meijer, Vicente Notario, Jane A. Endicott, Aude Echalier, Benoît Joseph, Bernard Marquet, François Liger, Michael H.G. Kubbutat, Christoph Schächtele, Peter Drueckes, Silvia Mateo-Lozano, Jonathan C. Morris, Olivier Lozach, Yoan Ferandin, Séverine Marionneau-Lambot, Oscar M. Tirado, Karima Bettayeb
Methods and Materials, Figure 4 Legend from Meriolins, a New Class of Cell Death–Inducing Kinase Inhibitors with Enhanced Selectivity for Cyclin-Dependent Kinases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518409c14552a25e83b2c37283b71aa5
https://doi.org/10.1158/0008-5472.22368009
https://doi.org/10.1158/0008-5472.22368009
Publikováno v:
European Journal of Organic Chemistry. 2022
Publikováno v:
Organofluorine Chemistry
Autor:
Florence Cadarossanesaib, Thierry Billard, Thibaut Iecker, François Liger, Christian Tourvieille, Didier Le Bars
Publikováno v:
European Journal of Organic Chemistry. 2019:6968-6972
Labeling of heterocycles with carbon-11 is generally performed through peripheral functionalizations and more scarcely inside heterocyclic core. Such less common approach usually requires preliminary multi-step synthesis of reactive species. Herein,
Autor:
Sophie Lancelot, François Liger, Thierry Billard, Fabien Chauveau, Pierre Courault, Anthony Fourier, Sandrine Bouvard, Stéphane Emery, David Meyronet, Luc Zimmer
Publikováno v:
Journal of Alzheimer's Disease
Journal of Alzheimer's Disease, IOS Press, 2020, 75 (4), pp.1329-1338. ⟨10.3233/JAD-191278⟩
Journal of Alzheimer's Disease, IOS Press, 2020, 75 (4), pp.1329-1338. ⟨10.3233/JAD-191278⟩
International audience; Background: The 5-HT 6 receptor is one of the most recently identified serotonin receptors in the central nervous system. Because of its role in memory and cognitive process, this receptor might be implicated in Alzheimer's di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3468b41046eeac82d6a1ee954e86dc66
https://doi.org/10.21203/rs.2.17017/v1
https://doi.org/10.21203/rs.2.17017/v1
Autor:
Kuo-Shyan Lin, Sergii Afonin, Justin J. Bailey, Pablo Barrio, Francois Benard, Vadim Bernard-Gauthier, Thierry Billard, Silvestre Buscemi, Fabien Caillé, Loïc P. Chêne, Julien A. Delbrouck, Kevin D. Dykstra, Myriem El Qacemi, Lori Fitz, Santos Fustero, Jéôme Graton, Oliver Gutbrod, Tadashi Honda, Luke Hunter, Naoko Ichiishi, Peter Jeschke, Klaus Jurkschat, Igor V. Komarov, Olga Koshkina, Shane W. Krska, Bertrand Kuhnast, Jean-Yves Le Questel, Frederic R. Leroux, François Liger, Bruno Linclau, Peter Maienfisch, Flora Mansour, Klaus Müller, Cormac D. Murphy, Iwao Ojima, Andrea Pace, William Palmer-Brown, Antonio Palumbo Piccionello, David M. Perrin, Fabrizio Pertusati, Ivana Pibiri, Elisa Pileggi, Laura Quinn, Stefano Rendine, Paul F. Richardson, Mélanie Roche, Raquel Román, Marta Saccomanno, Ralf Schirrmacher, Esther Schirrmacher, Daniel M. Sedgwick, Michaela Serpi, Simon Specklin, Mangala Srinivas, Xander Staal, Andrés A. Trabanco, Anne S. Ulrich, Mathieu Verdurand, Stéphane P. Vincent, Carmen Wängler, Björn Wängler, Li Xing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e6cf90fd569787b54636f8c72764fe
https://doi.org/10.1016/b978-0-12-812733-9.01002-3
https://doi.org/10.1016/b978-0-12-812733-9.01002-3
Publikováno v:
Neuroscience Letters
Neuroscience Letters, Elsevier, 2016, 612, pp.74-79. ⟨10.1016/j.neulet.2015.11.042⟩
Neuroscience Letters, Elsevier, 2016, 612, pp.74-79. ⟨10.1016/j.neulet.2015.11.042⟩
International audience; Using positron emission tomography (PET), the present study assessed the binding of [11C]flumazenil to GABA-A receptors in anesthetized rats following a single intravenous injection of an active dose of either etifoxine (25 mg