Zobrazeno 1 - 10
of 16
pro vyhledávání: '"François Halloy"'
Autor:
Alyssa C. Hill, J. Philipp Becker, Daria Slominski, François Halloy, Christoffer Søndergaard, Jacob Ravn, Jonathan Hall
Publikováno v:
ACS Omega, Vol 8, Iss 43, Pp 40463-40481 (2023)
Externí odkaz:
https://doaj.org/article/6927691e26e242e491ae5fccd4099005
Autor:
François Halloy, Annabelle Biscans, Katherine E. Bujold, Alexandre Debacker, Alyssa C. Hill, Aurélie Lacroix, Olivia Luige, Roger Strömberg, Linda Sundstrom, Jörg Vogel, Alice Ghidini
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 313-332 (2022)
RNA-based therapeutics are emerging as a powerful platform for the treatment of multiple diseases. Currently, the two main categories of nucleic acid therapeutics, antisense oligonucleotides and small interfering RNAs (siRNAs), achieve their therapeu
Externí odkaz:
https://doaj.org/article/cd8fb0a6285b407a8a63465d0c07a69f
Autor:
Elena Moroz, Soo Hyeon Lee, Ken Yamada, François Halloy, Saúl Martínez-Montero, Hartmut Jahns, Jonathan Hall, Masad J Damha, Bastien Castagner, Jean-Christophe Leroux
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Nucleic acid therapy can be beneficial for the local treatment of gastrointestinal diseases that currently lack appropriate treatments. Indeed, several oligonucleotides (ONs) are currently progressing through clinical trials as potential treatments f
Externí odkaz:
https://doaj.org/article/a4adba38bc78417ebcd5e8745c9d45ac
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2537
We describe methods to follow the fate of oligonucleotides after their injection into experimental animals. The quantitation in various tissues, blood or bone marrow cells is possible by chemical ligation PCR. This method works independently of chemi
Publikováno v:
Methods in Molecular Biology ISBN: 9781071625200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbf9e7b264eaf80a9b28a42d2c8e0c77
https://doi.org/10.1007/978-1-0716-2521-7_19
https://doi.org/10.1007/978-1-0716-2521-7_19
Publikováno v:
ChemMedChem. 16(22)
Single-stranded phosphorothioate (PS) oligonucleotide drugs have shown potential for the treatment of several rare diseases. However, a barrier to their widespread use is that they exhibit activity in only a narrow range of tissues. One way to circum
Autor:
Jonathan Hall, Daniel Schümperli, Alexandre Theocharides, Anna Elisabeth Minder, Nicole Wildner-Verhey van Wijk, Veronika Lysenko, Jessica Jucker, Elisabeth I. Minder, Xiaoye Schneider-Yin, Jasmin Barman-Aksözen, François Halloy, Alice Ghidini, Chia Pei Grubenmann, Marc-David Ruepp, Pavithra S. Iyer
Publikováno v:
Cell chemical biology. 28(8)
Erythropoietic protoporphyria (EPP) is a rare disease in which patients experience severe light sensitivity. It is caused by a deficiency of ferrochelatase (FECH), the last enzyme in heme biosynthesis (HBS). The lack of FECH causes accumulation of it
Autor:
Alexandre Theocharides, Alice Ghidini, Paulina Ćwiek, Nicole Wildner-Verhey van Wijk, Jonathan Hall, Elisabeth I. Minder, Jasmin Barman-Aksözen, François Halloy, Pavithra S. Iyer, Xiaoye Schneider-Yin, Daniel Schümperli
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 48 (9)
Nucleic Acids Research, 48 (9)
Erythropoietic protoporphyria (EPP) is a rare genetic disease in which patients experience acute phototoxic reactions after sunlight exposure. It is caused by a deficiency in ferrochelatase (FECH) in the heme biosynthesis pathway. Most patients exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d611b75c366a2bbd66ec0a4ddeaee46
Publikováno v:
Helvetica Chimica Acta. 102
Autor:
Elisabeth I. Minder, Pavithra S. Iyer, Jonathan Hall, Anna Elisabeth Minder, Daniel Schümperli, Xiaoye Schneider-Yin, Jasmin Barman-Aksözen, François Halloy
Publikováno v:
Molecular Genetics and Metabolism, 128 (3)
Deficiency in ferrochelatase (FECH), the last enzyme in the heme biosynthetic pathway, leads to an accumulation of protoporphyrin IX (PPIX) that causes a severely painful phototoxic reaction of the skin in patients with erythropoietic protoporphyria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da773e753b248c26aa3429fce1bcb20
https://hdl.handle.net/20.500.11850/385685
https://hdl.handle.net/20.500.11850/385685