Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Fran Hausman"'
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75213 (2013)
Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken. Ninety-nine percent of mouse gene
Externí odkaz:
https://doaj.org/article/e48f9c2749b34a7f8c6f320d8dc3d7b4
Autor:
Dennis R. Trune, Carol J. MacArthur, Fran Hausman, Dongseok Choi, Katherine D. Shives, J. Beth Kempton
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 128:134S-138S
Objectives: Glucocorticoids are given for sensorineural hearing loss, but little is known of their molecular impact on the inner ear. Furthermore, in spite of claims of improved hearing recovery with intratympanic delivery of steroids, no studies hav
Publikováno v:
Otology & Neurotology. 36:1089-1095
The inner ear (IE) endothelium is capable of responding to therapeutic steroids by altering the local expression of cytokine and ion homeostasis genes that impact inflammation and fluid regulation.Glucocorticoids are often given transtympanically for
Studies were designed to ascertain the impact of chronic middle ear infection on the numerous ion and water channels, transporters, and tissue remodeling genes in the inner and middle ear.Permanent sensorineural hearing loss is a significant problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa84fa07a1b0276e3f9cc2c463bcd1c
https://europepmc.org/articles/PMC3548044/
https://europepmc.org/articles/PMC3548044/
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e75213 (2013)
PLoS ONE, Vol 8, Iss 10, p e75213 (2013)
Objective Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken. Ninety-nine percent of