The MAPK pathway and Egr-1 mediate stress-related behavioral effects of glucocorticoids

Autor: Pier Vincenzo Piazza, Jean-Michel Revest, Aline Desmedt, Françoise Rougé-Pont, Francesco Di Blasi, Pierre Kitchener, François Tronche, Marc Turiault

Publikováno v: Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2005, 8, pp.664-672; 835
Nature Neuroscience, Nature Publishing Group, 2005, 8 (5), pp.664-672. ⟨10.1038/nn1441⟩
Nature Neuroscience, 2005, 8 (5), pp.664-672. ⟨10.1038/nn1441⟩

International audience; Many of the behavioral consequences of stress are mediated by the activation of the glucocorticoid receptor by stress-induced high levels of glucocorticoid hormones. To explore the molecular mechanisms of these effects, we com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b15557712b6528bcd7d87141596993b
https://doi.org/10.1038/nn1441

BDNF-TrkB signaling through Erk1/2MAPK phosphorylation mediates the enhancement of fear memory induced by glucocorticoids

Autor: P.V. Piazza, Françoise Rougé-Pont, A. Y. Le Roux, N Kaouane, J-M Revest, Aline Desmedt, Monique Vallée, Valérie Roullot-Lacarrière, F Tronche, Fernando Kasanetz

Publikováno v: Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2014, 19 (9), pp.1001-1009. ⟨10.1038/mp.2013.134⟩

International audience; Activation of glucocorticoid receptors (GR) by glucocorticoid hormones (GC) enhances contextual fear memories through the activation of the Erk1/2(MAPK) signaling pathway. However, the molecular mechanism mediating this effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad88ff5dd473f49b2f6ae7ffa003fed6
https://hal.archives-ouvertes.fr/hal-02323699

Distinct functions of the two isoforms of dopamine D2 receptors

Autor: Françoise Rougé-Pont, Alessandro Usiello, Pier Vincenzo Piazza, Andrée Dierich, Emiliana Borrelli, Marianne LeMeur, Ja Hyun Baik, Roberto Picetti

Publikováno v: Nature. 408:199-203

Signalling through dopamine D2 receptors governs physiological functions related to locomotion, hormone production and drug abuse1,2,3,4,5,6,7. D2 receptors are also known targets of antipsychotic drugs that are used to treat neuropsychiatric disorde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f063044e2bd7dd33e6c5fe53907ff95
https://doi.org/10.1038/35041572

The dopaminergic hyper-responsiveness of the shell of the nucleus accumbens is hormone-dependent

Autor: Michel Le Moal, Djoher Nora Abrous, Michel Barrot, Michela \\'Micky\\' Marinelli, Françoise Rougé-Pont, Pier Vincenzo Piazza

Publikováno v: European Journal of Neuroscience. 12:973-979

The dopaminergic projection to the shell of the nucleus accumbens is the most reactive to stress, reward and drugs of abuse and this subregion of the nucleus accumbens is also considered a target of therapeutic effects of atypical antipsychotic drugs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75fec9705690e1062e602a4e39fcf62c
https://doi.org/10.1046/j.1460-9568.2000.00996.x

Functional heterogeneity in dopamine release and in the expression of Fos-like proteins within the rat striatal complex

Autor: Françoise Rougé-Pont, Michel Le Moal, Michel Barrot, Pier Vincenzo Piazza, Djoher Nora Abrous, Michela \\'Micky\\' Marinelli

Publikováno v: European Journal of Neuroscience. 11:1155-1166

The dorsolateral striatum, and the core and shell of the nucleus accumbens are three major anatomical regions of the striatal complex. The shell is considered as a part of the extended amygdala, and is involved in the control of motivation and reward

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f570ed1463f0f62aeca5f032d7b3e11c
https://doi.org/10.1046/j.1460-9568.1999.00525.x