Zobrazeno 1 - 10 of 51 pro vyhledávání: '"Françoise Roquet"'
1
Akademický článek
Loss of LpqM proteins in Mycobacterium abscessus is associated with impaired intramacrophage survival
Autor: Yves-Marie Boudehen, Wassim Daher, Françoise Roquet-Baneres, Laurent Kremer
Publikováno v: Microbiology Spectrum, Vol 12, Iss 5 (2024)
ABSTRACTMycobacterium abscessus, an emerging pathogen responsible for severe pulmonary infections in cystic fibrosis patients, displays either a smooth (S) or a rough (R) morphotype. Infections with M. abscessus R are associated with increased pathog
Externí odkaz: https://doaj.org/article/d2564dadd2b0437db6c51d1cf43352c3
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2
Akademický článek
Mycobacteriophage–antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus
Autor: Matt D. Johansen, Matthéo Alcaraz, Rebekah M. Dedrick, Françoise Roquet-Banères, Claire Hamela, Graham F. Hatfull, Laurent Kremer
Publikováno v: Disease Models & Mechanisms, Vol 14, Iss 9 (2021)
Infection by multidrug-resistant Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF) patients, leaving clinicians with few therapeutic options. A compassionate study showed the clinical improvement of a CF patient with a dissemi
Externí odkaz: https://doaj.org/article/00e703d3ee684e6691f9ede96b747d7d
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4
In Vitro and In Vivo Efficacy of NITD-916 against Mycobacterium fortuitum
Autor: Françoise Roquet-Banères, Matthéo Alcaraz, Claire Hamela, Jan Abendroth, Thomas E. Edwards, Laurent Kremer
Publikováno v: Antimicrobial Agents and Chemotherapy. 67
Mycobacterium fortuitum represents one of the most clinically relevant rapid-growing mycobacterial species. Treatments are complex due to antibiotic resistance and to severe side effects of effective drugs, prolonged time of treatment, and co-infecti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e8f4d5014d686c97869df9fe7a9c0d2
https://doi.org/10.1128/aac.01607-22
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5
Akademický článek
Rational design and microwave-promoted synthesis of triclosan-based dimers: targeting InhA for anti-mycobacterial profiling
Autor: ­ ­Shekhar, Francoise Roquet-Banères, Amit Anand, Laurent Kremer, Vipan Kumar
Publikováno v: Royal Society Open Science, Vol 11, Iss 10 (2024)
A set of alkyl-/1H-1,2,3-triazole-based dimers was strategically designed and synthesized to evaluate their in vitro anti-mycobacterial activities against Mycobacterium tuberculosis and the non-tuberculous Mycobacterium abscessus strains. Systematic
Externí odkaz: https://doaj.org/article/73fc0b9462944bad93a74f31ffd0c078
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6
[Mycobacterium abscessus, a model of resistance to multiple antibiotic classes]
Autor: Morgane, Illouz, Matthéo, Alcaraz, Françoise, Roquet-Banères, Laurent, Kremer
Publikováno v: Medecine sciences : M/S. 37(11)
Mycobacterium abscessus is an environmental fast-growing, non-tuberculous mycobacterium responsible for severe lung infections, especially in patients with underlying lung disorders such as cystic fibrosis. The standard chemotherapy combines a b-lact
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6d11bb5df1593ee9188d19a2e1d59f00
https://pubmed.ncbi.nlm.nih.gov/34851275
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7
Mycobacterium abscessus, un modèle de résistance aux différentes classes d’antibiotiques
Autor: Matthéo Alcaraz, Laurent Kremer, Morgane Illouz, Françoise Roquet-Banères
Publikováno v: médecine/sciences
médecine/sciences, EDP Sciences, 2021, 37 (11), pp.993-1001. ⟨10.1051/medsci/2021164⟩
Mycobacterium abscessusest une bactérie non tuberculeuse, environnementale, à croissance rapide, qui est responsable d’infections pulmonaires sévères, notamment chez les patients atteints de mucoviscidose. Le traitement actuel combine l’utili
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362fe8c15d1c9c1764fd3db0bbcd63ad
https://hal.archives-ouvertes.fr/hal-03462547/document
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8
Mycobacteriophage–antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus
Autor: Françoise Roquet-Banères, Graham F. Hatfull, Rebekah M. Dedrick, Claire Hamela, Matt D. Johansen, Laurent Kremer, Matthéo Alcaraz
Publikováno v: Disease Models & Mechanisms
Disease Models & Mechanisms, Cambridge Company of Biologists, 2021, 14 (9), pp.dmm049159. ⟨10.1242/dmm.049159⟩
Disease Models & Mechanisms, 2021, 14 (9), pp.dmm049159. ⟨10.1242/dmm.049159⟩
Disease Models & Mechanisms, Vol 14, Iss 9 (2021)
Infection by multidrug-resistant Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF) patients, leaving clinicians with few therapeutic options. A compassionate study showed the clinical improvement of a CF patient with a dissemi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba7733fc1f6c7807cde1c402b96fd3e
https://doi.org/10.1242/dmm.049159
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9
Designing quinoline-isoniazid hybrids as potent anti-tubercular agents inhibiting mycolic acid biosynthesis
Autor: Matthéo Alcaraz, Bharvi Sharma, Françoise Roquet-Banères, Cyril Conde, Thierry Cochard, Franck Biet, Vipan Kumar, Laurent Kremer
Publikováno v: European Journal of Medicinal Chemistry. 239:114531
Isoniazid is a cornerstone of modern tuberculosis (TB) therapy and targets the enoyl ACP reductase InhA, a key enzyme in mycolic acid biosynthesis. InhA is still a promising target for the development of new anti-TB drugs. Herein, we report the desig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f8fe4de17fcbb92b9c92ea46e347cf
https://doi.org/10.1016/j.ejmech.2022.114531
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10
Design and synthesis of 4-Aminoquinoline-isoindoline-dione-isoniazid triads as potential anti-mycobacterials
Autor: Oluwakemi Ebenezer, Laurent Kremer, Parvesh Singh, Anu Rani, Paul Awolade, Françoise Roquet-Banères, Vipan Kumar, Matt D. Johansen, Sumanjit
Publikováno v: Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, 2020, 30 (22), pp.127576. ⟨10.1016/j.bmcl.2020.127576⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2020, 30 (22), pp.127576. ⟨10.1016/j.bmcl.2020.127576⟩
International audience; A series of 4-aminoquinoline-isoindoline-dione-isoniazid triads were synthesized and assessed for their anti-mycobacterial activities and cytotoxicity. Most of the synthesized compounds exhibited promising activities against t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389c017dcecc86a28657b913c297d748
https://www.hal.inserm.fr/inserm-03082751/file/4-aminoquinoline-isoindoline-dione-INH-BMCL.pdf
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