Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Françoise Nepveu"'
Autor:
Monivan Chhour, Pierre Perio, Regis Gayon, Hélène Ternet-Fontebasso, Gilles Ferry, Françoise Nepveu, Jean A. Boutin, Jan Sudor, Karine Reybier
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The balance between detoxification and toxicity is linked to enzymes of the drug metabolism Phase I (cytochrome P450 or oxidoreductases) and phase II conjugating enzymes (such as the UGTs). After the reduction of quinones, the product of the reaction
Externí odkaz:
https://doaj.org/article/26bc792e0c0542f4b230c4e3914b1c67
Autor:
Monivan Chhour, Agnès Aubouy, Sandra Bourgeade-Delmas, Pierre Pério, Hélène Ternet-Fontebasso, Mahamane Haidara, Gilles Ferry, Françoise Nepveu, Jean A. Boutin, Karine Reybier
Publikováno v:
Molecules, Vol 24, Iss 20, p 3697 (2019)
Dunnione, a natural product isolated from the leaves of Streptocarpus dunnii (Gesneriaceae), acts as a substrate for quinone-reductases that may be associated with its antimalarial properties. Following our exploration of reactive oxygen species-prod
Externí odkaz:
https://doaj.org/article/994842cb1af14120a38022e358355da1
Publikováno v:
Arabian Journal of Chemistry, Vol 10, Iss S2, Pp S3040-S3047 (2017)
New series of 10-anilino-9-alkyl-12-aryl-10,12-dihydro-11H-benzo[5,6] chromeno [2,3-d]pyrimidin-11-ones 5(a–e) and 9-anilino-10-alkyl-7-aryl-7,9-dihydro-8H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-ones 6(a–f) were prepared in three steps with microwa
Externí odkaz:
https://doaj.org/article/14315ad98e7d42248dbc4b5d524c96cc
Autor:
Aida Chaker, Ennaji Najahi, Olivier Chatriant, Alexis Valentin, Nathan Téné, Michel Treilhou, Fakher Chabchoub, Françoise Nepveu
Publikováno v:
Arabian Journal of Chemistry, Vol 10, Iss S2, Pp S2464-S2470 (2017)
A new series of 3-substituted-2,1-benzisoxazoles (anthranils) were prepared by different methods and characterized by spectroscopic methods and mass spectrometry. These 2,1-benzisoxazoles were tested in vitro for their antiplasmodial activity on a ch
Externí odkaz:
https://doaj.org/article/c2e4456d4fd54f79b86241bdd3caaf5e
Autor:
Ennaji Najahi, Pierre Perio, Etienne Hollande, Françoise Nepveu, Rym Abidi, Amani Mejai, Maria Rosalia Pasca, Nambinina V. Rakotoarivelo
Publikováno v:
JOURNAL OF ADVANCES IN CHEMISTRY. 16:5387-5394
Despite strong indications of antimycobacterial activities for clitocybins reported since 1945, no reports linking chemical structure and activity have been reported in the literature since then. In this study, we synthesized some clitocybin derivati
Publikováno v:
Molecules, Vol 15, Iss 12, Pp 8841-8855 (2010)
In this paper we present the room temperature synthesis of a novel serie of 1,4-disubstituted-1,2,3-triazoles 4a-l by employing the (3 + 2) cycloaddition reaction of pyrimidinones containing alkyne functions with different model azides in the presenc
Externí odkaz:
https://doaj.org/article/b21500e3bf604470b7ab65484bc18760
Autor:
Monique Berger, Vincent Farines, Karine Reybier, Aude Verger, Jean Daydé, Vassilia Théodorou, Françoise Nepveu, Marie-Carmen Monje
Publikováno v:
Food Technology and Biotechnology, Vol 44, Iss 4, Pp 493-498 (2006)
The aim was to study the relationship between the antioxidant capacity and the isoflavone content of soybean extracts depending on both geographic origin and cultivar. Soybean samples were obtained from two soybean seed parts, germ and cotyledon, fro
Externí odkaz:
https://doaj.org/article/9cf082ec94074f38917877a67cdd5c21
Autor:
Laure-Estelle Cassagnes, Nambinina Rakotoarivelo, Serena Sirigu, Pierre Pério, Ennaji Najahi, Léonard M. G. Chavas, Andrew Thompson, Régis Gayon, Gilles Ferry, Jean A. Boutin, Alexis Valentin, Karine Reybier, Françoise Nepveu
Publikováno v:
Molecules, Vol 22, Iss 2, p 210 (2017)
Indolone-N-oxides have antiplasmodial properties against Plasmodium falciparum at the erythrocytic stage, with IC50 values in the nanomolar range. The mechanism of action of indolone derivatives involves the production of free radicals, which follows
Externí odkaz:
https://doaj.org/article/925a264a785f403382c72dca47079d4a
Autor:
Maria Carmina Pau, Antonella Pantaleo, Francesco Michelangelo Turrini, Patrizia Virdis, Claudio Fozza, Françoise Nepveu, Philip S. Low, Giuseppe Marchetti, Karine Reybier, Ioannis Tsamesidis
Publikováno v:
Antioxidants
Volume 9
Issue 8
Antioxidants, 2020, 9 (8), pp.753. ⟨10.3390/antiox9080753⟩
Antioxidants, Vol 9, Iss 753, p 753 (2020)
Volume 9
Issue 8
Antioxidants, 2020, 9 (8), pp.753. ⟨10.3390/antiox9080753⟩
Antioxidants, Vol 9, Iss 753, p 753 (2020)
International audience; Although artemisinin-based combination therapies (ACTs) treat Plasmodium falciparum malaria effectively throughout most of the world, the recent expansion of ACT-resistant strains in some countries of the Greater Mekong Subreg
Publikováno v:
Molecular pharmacology. 98(5)
N-ribosyldihydronicotinamide:quinone oxidoreductase 2 (NQO2/QR2, Enzyme Commission number 1.10.99.2) is a cytosolic enzyme, abundant in the liver and variably expressed in mammalian tissues. Cloned 30 years ago, it was characterized as a flavoenzyme