Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Françoise Levinthal"'
Publikováno v:
Science. 259:960-963
To investigate the mechanism of interaction of the toxin colicin E1 with membranes, three cysteine substitution mutants and the wild type of the channel-forming fragment were spin labeled at the unique thiol. Time-resolved interaction of these labele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172ef1345b07ac465ca53ecfd1470a5c
https://doi.org/10.1126/science.8382373
https://doi.org/10.1126/science.8382373
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 11:254-262
The molecularity of the ion channel formed by peptide fragments of colicin has taken on particular significance since the length of the active peptide has been shown to be less than 90 amino acids and the lumen size at least 8 A. Cell survival experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38e880e8a2fc1ce4183a54ed2c7552bc
https://doi.org/10.1002/prot.340110404
https://doi.org/10.1002/prot.340110404
Publikováno v:
Neuron. 1:367-376
To search for genes involved in determining the morphology of individual neuronal types, a cDNA library was constructed from postnatal day 13 mouse cerebellum. From this library, 2 clones, L7 and L19, were isolated by a differential hybridization pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3493a01545228c95da46fa0c96344f3
https://doi.org/10.1016/0896-6273(88)90186-9
https://doi.org/10.1016/0896-6273(88)90186-9
Publikováno v:
Proteins: Structure, Function, and Genetics. 6:294-305
Colicin E1 is an E. coli plasmid-encoded water-soluble protein that spontaneously inserts into lipid membranes to form a voltage-gated ion channel. We have employed a novel approach in which site-directed mutagenesis is used to provide highly specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ba9bad4924960d8b56733b56d513c2
https://doi.org/10.1002/prot.340060312
https://doi.org/10.1002/prot.340060312
Publikováno v:
Cold Spring Harbor symposia on quantitative biology. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa77fe947f09f1841fa995ea151dfc4
https://pubmed.ncbi.nlm.nih.gov/1065532
https://pubmed.ncbi.nlm.nih.gov/1065532
Autor:
Qian Liu, Cyrus Levinthal, Françoise Levinthal, Stephen L. Slatin, V. Crozel, Alan Finkelstein
Publikováno v:
Proteins. 1(3)
Cleavage of colicin E1 molecules with a variety of proteases or with cyanogen bromide (CNBr) generates COOH-terminal fragments which have channel-forming activity similar to that of intact colicin in planar lipid bilayer membranes. The smallest chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037fd9949d0bae3282b5ec0966b28073
https://pubmed.ncbi.nlm.nih.gov/2453053
https://pubmed.ncbi.nlm.nih.gov/2453053