Antifibroblast antibodies from systemic sclerosis patients bind to α-enolase and are associated with interstitial lung disease

Autor: Alice Bérezné, Françoise Hotellier, Benjamin Terrier, Cédric Broussard, Philippe Guilpain, Luc Camoin, Luc Mouthon, Gérald Simonneau, Mathieu C. Tamby, Nicolas Tamas, Loïc Guillevin, Marc Humbert

Publikováno v: Annals of the Rheumatic Diseases. 69:428-433

Objective:To identify target antigens of antifibroblast antibodies (AFA) in systemic sclerosis (SSc) patients.Patients and Methods:In the first part, sera from 24 SSc patients (12 with pulmonary arterial hypertension (PAH) and 12 without) and 36 idio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09ec3951111aeed3b6b985f3e325f32
https://doi.org/10.1136/ard.2008.104299

Pharmacokinetics and tolerance of flunitrazepam in neonates and in infants

Autor: Philippe Hubert, Gérard Pons, Chantal Wood, Philippe d'Athis, Evelyne Werner, Françoise Hotellier, Jean-Marc Tréluyer, Mostafa Mokhtari, Elisabeth Rey, Philippe Jouvet, A. Pariente-Khayat, Georges Olive

Publikováno v: Europe PubMed Central

Objective To study the pharmacokinetics of flunitrazepam (used for sedation in neonates and infants), to determine the influence of both gestational and postnatal age on the pharmacokinetic parameters, and to analyze the relationship between the hemo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3699499f61e4a4df131ff961cf4f5f
https://doi.org/10.1053/cp.1999.v66.100596001

A Generic Approach for the Purification of Signaling Complexes That Specifically Interact with the Carboxyl-terminal Domain of G Protein-coupled Receptors

Autor: Philippe Delagrange, Pascal Maurice, Gilles Ferry, Guilhem Clary, Julien Mozo, Cédric Broussard, Philippe Chafey, Ralf Jockers, Jean-Luc Guillaume, Luc Camoin, Jean A. Boutin, Françoise Hotellier, Avais M. Daulat

Publikováno v: Molecular and Cellular Proteomics
Molecular and Cellular Proteomics, 2008, 7 (8), pp.1556-69. ⟨10.1074/mcp.M700435-MCP200⟩
Molecular and Cellular Proteomics, American Society for Biochemistry and Molecular Biology, 2008, 7 (8), pp.1556-69. ⟨10.1074/mcp.M700435-MCP200⟩

International audience; G protein-coupled receptors (GPCRs) constitute the largest family of membrane receptors and are major drug targets. Recent progress has shown that GPCRs are part of large protein complexes that regulate their activity. We pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44496b516014748a2aaa9f747b40db6
https://hal.science/hal-02348044/document

Nauclefine et naucletine deux nouveaux alcaloides de type indoloquinolizidine isoles du Nauclea latifolia

Autor: Delaveau P, Jean-Louis Pousset, Françoise Hotellier

Publikováno v: Phytochemistry. 14:1407-1409

From the root bark of Nauclea latifolia several indoloquinolizidine alkaloids were isolated. Two are known compounds: angustine and angustoline. The other two, nauclefine and naucietine, are new products.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14a1022bf8b65126ec1939819481b33e
https://doi.org/10.1016/s0031-9422(00)98638-2