Výsledky vyhledávání - "Françoise Gobet"

Akademický článek

The neuropeptide substance P regulates aldosterone secretion in human adrenals

Autor: Julien Wils, Céline Duparc, Anne-Françoise Cailleux, Antoine-Guy Lopez, Caroline Guiheneuf, Isabelle Boutelet, Hadrien-Gaël Boyer, Christophe Dubessy, Saloua Cherifi, Bruno Cauliez, Françoise Gobet, Guillaume Defortescu, Jean-François Ménard, Estelle Louiset, Hervé Lefebvre

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

Adrenal aldosterone production is regulated by plasma angiotensin and potassium levels. Here the authors report that the neuropeptide substance P stimulates aldosterone production via neurokinin type 1 receptors (NK1R), and report a proof-of-concept

Externí odkaz: https://doaj.org/article/48ddfb7cf8b04ad380242a0ab5764f18

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Akademický článek

The neuropeptide 26RFa in the human gut and pancreas: potential involvement in glucose homeostasis

Autor: Gaëtan Prévost, Marie Picot, Marie-Anne Le Solliec, Arnaud Arabo, Hind Berrahmoune, Mouna El Mehdi, Saloua Cherifi, Alexandre Benani, Emmanuelle Nédélec, Françoise Gobet, Valéry Brunel, Jérôme Leprince, Hervé Lefebvre, Youssef Anouar, Nicolas Chartrel

Publikováno v: Endocrine Connections, Vol 8, Iss 7, Pp 941-951 (2019)

Objective: Recent studies performed in mice revealed that the neuropeptide 26RFa regulates glucose homeostasis by acting as an incretin and by increasing insulin sensitivity. However, in humans, an association between 26RFa and the regulation of gluc

Externí odkaz: https://doaj.org/article/58db3563f3444deaba9118db380d275d

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Clinical interest of PD-L1 immuno-histochemistry expression as a predictive factor of Bacillus Calmette Guerin (BCG) efficacy in refractory high-risk non-muscle-invasive bladder cancer (NMIBC)

Autor: Clara Delcourt, Andre Gillibert, François Xavier Nouhaud, Jacques Irani, Christian Pfister, Françoise Gobet, Pierre Gemival, Jean Christophe Sabourin, Sophie Ferlicot

Publikováno v: World Journal of Urology
World Journal of Urology, Springer Verlag, 2020, 38 (6), pp.1517-1524. ⟨10.1007/s00345-019-02896-3⟩

International audience; Objective: To assess PD-L1 expression in tumor (TC) and tumor infiltrating immune cells (IC) as a predictive factor of BCG therapy failure in high-risk NMIBC.Materials and methods: Patients treated with complete resection foll

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e641e31eeff803e21497727957e4940
https://doi.org/10.1007/s00345-019-02896-3

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Prognostic Impact of pT3 Subclassification in a Multicentre Cohort of Patients with Urothelial Carcinoma of the Renal Pelvicalyceal System Undergoing Radical Nephroureterectomy: A Propensity Score-weighted Analysis After Central Pathology Review

Publikováno v: European Urology Focus
European Urology Focus, Elsevier, 2020, 7 (5), pp.1075-1083. ⟨10.1016/j.euf.2020.10.004⟩

Background The current pathological tumour-node-metastasis (pTNM) classification for upper tract urothelial carcinoma (UTUC) does not include any risk stratification of pT3 renal pelvicalyceal tumours. Objective To assess the prognostic impact of pT3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eeb5bd5bd915d2d0f0bdb086df7d92e
https://hal.umontpellier.fr/hal-03274050

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The neuropeptide substance P regulates aldosterone secretion in human adrenals

Autor: Saloua Cherifi, Guillaume Defortescu, Julien Wils, Estelle Louiset, Françoise Gobet, C. Guiheneuf, Céline Duparc, Antoine-Guy Lopez, Christophe Dubessy, Anne Cailleux, Hadrien-Gaël Boyer, Bruno Cauliez, Hervé Lefebvre, J.F. Ménard, Isabelle Boutelet

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.2673. ⟨10.1038/s41467-020-16470-8⟩
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications, 2020, 11 (1), pp.2673. ⟨10.1038/s41467-020-16470-8⟩

Aldosterone, produced by the adrenals and under the control of plasma angiotensin and potassium levels, regulates hydromineral homeostasis and blood pressure. Here we report that the neuropeptide substance P (SP) released by intraadrenal nerve fibres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1b0e11d36f8eaf1339618f125414ce
https://hal-normandie-univ.archives-ouvertes.fr/hal-02861854/file/s41467-020-16470-8(1).pdf

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Illicit Upregulation of Serotonin Signaling Pathway in Adrenals of Patients With High Plasma or Intra-Adrenal ACTH Levels

Autor: Olivier Chabre, Céline Duparc, Mathilde Sibony, Mari Suzuki, Philippe Touraine, Fideline Bonnet-Serrano, Estelle Louiset, Constantine A. Stratakis, Françoise Gobet, Jacques Young, Julie Le Mestre, Hervé Lefebvre, Jérôme Bertherat, Yves Reznik, Gérald Raverot

Publikováno v: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2019, 104 (11), pp.4967-4980. ⟨10.1210/jc.2019-00425⟩
Journal of Clinical Endocrinology and Metabolism, 2019, 104 (11), pp.4967-4980. ⟨10.1210/jc.2019-00425⟩
J Clin Endocrinol Metab

Context In the human adrenal, serotonin (5-HT), released by mast cells stimulates corticosteroid secretion through activation of type 4 serotonin receptors (5-HT4R). In primary pigmented nodular adrenocortical disease cells, activation of the cAMP/pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c805165afd6ae81f20b4f48b590f5f
https://hal-normandie-univ.archives-ouvertes.fr/hal-02419863

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Abnormal serotonin regulatory loop in adrenals of patients with Cushing's syndrome and 21-hydroxylase deficiency

Autor: Jacques Young, Estelle Louiset, Jérôme Bertherat, Olivier Chabre, Fideline Bonnet-Serrano, Mathilde Sibony, Herve Lefebvre, Yves Reznik, Celine Duparc, Françoise Gobet, Mestre Julie Le, Philippe Touraine, Gerald Raverot

Publikováno v: 21st European Congress of Endocrinology-ECE 2019
21st European Congress of Endocrinology-ECE 2019, May 2019, Lyon, France

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a1655467b424947819a998f8850c4f
https://doi.org/10.1530/endoabs.63.p814

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The neuropeptide 26RFa in the human gut and pancreas: potential involvement in glucose homeostasis

Autor: Nicolas Chartrel, Marie-Anne Le Solliec, Françoise Gobet, Hind Berrahmoune, Valéry Brunel, Mouna El Mehdi, Saloua Cherifi, Youssef Anouar, Marie Christine Picot, Gaëtan Prévost, Alexandre Benani, Emmanuelle Nédélec, Arnaud Arabo, Jérôme Leprince, Hervé Lefebvre

Publikováno v: Endocrine Connections 7 (8), 941-951. (2019)
Endocrine Connections
Endocrine Connections, BioScientifica Ltd., 2019, 8 (7), pp.941-951. ⟨10.1530/ec-19-0247⟩
Endocrine Connections, Vol 8, Iss 7, Pp 941-951 (2019)
Endocrine Connections, BioScientifica, 2019, 8 (7), pp.941-951. ⟨10.1530/EC-19-0247⟩
Endocrine Connections, 2019, 8 (7), pp.941-951. ⟨10.1530/ec-19-0247⟩

Objective Recent studies performed in mice revealed that the neuropeptide 26RFa regulates glucose homeostasis by acting as an incretin and by increasing insulin sensitivity. However, in humans, an association between 26RFa and the regulation of gluco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a4e40cc9f70c1323e607ac39de6399
http://prodinra.inra.fr/record/476503

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