Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Françoise Brizard"'
Autor:
Maria Pilar Gallego Hernanz, José Miguel Torregrosa Diaz, Nathalie Sorel, Arthur Bobin, Elodie Dindinaud, Sabrina Bouyer, Deborah Desmier, Françoise Brizard, Xavier Leleu, Natacha Maillard, Jean‐Claude Chomel
Publikováno v:
Cancer Medicine, Vol 8, Iss 4, Pp 1765-1770 (2019)
Abstract A large variety of molecular rearrangements of the NUP98 gene have been described in the past decades (n = 72), involving fusion partners coding for different transcription factors, chromatin modifying enzymes, as well as various cytosolic p
Externí odkaz:
https://doaj.org/article/7ab3ed96ccfb450081bf4fb40af3033f
Autor:
Niels Moya, Françoise Brizard, Jean-Claude Chomel, Deborah Desmier, Jose Miguel Torregrosa Diaz, Nathalie Sorel, Xavier Leleu, Maria Pilar Gallego Hernanz, Sabrina Bouyer, Mélanie Chollet, N. Maillard
Publikováno v:
Leukemia & Lymphoma. 61:1709-1713
The genomic landscape of acute myeloid leukemia (AML) is now well known, and NPM1 and TET2 are among the most commonly mutated genes [1,2]. NPM1 insertions are frequently detected in AML, especiall...
Autor:
Natacha Maillard, Nathalie Sorel, Jose Miguel Torregrosa Diaz, Jean-Claude Chomel, Arthur Bobin, Deborah Desmier, Xavier Leleu, Sabrina Bouyer, Françoise Brizard, Maria Pilar Gallego Hernanz, Elodie Dindinaud
Publikováno v:
Cancer Medicine, Vol 8, Iss 4, Pp 1765-1770 (2019)
Cancer Medicine
Cancer Medicine
A large variety of molecular rearrangements of the NUP98 gene have been described in the past decades (n = 72), involving fusion partners coding for different transcription factors, chromatin modifying enzymes, as well as various cytosolic proteins.
Autor:
Christelle Dupraz, Jean-Claude Chomel, Françoise Brizard, Anna Raimbault, Nathalie Sorel, Valentina Pierini, Frédéric Millot, Cristina Mecucci, Thibault Depaire
This report describes the first case of NUP98-HHEX rearrangement observed in pediatric acute myeloid leukemia (AML). The oncogenic potential of NUP98 fusions was first documented in hematological m...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055b4deed454c4b7e0c461618b191228
http://hdl.handle.net/11391/1502561
http://hdl.handle.net/11391/1502561
Autor:
Barbara De Moerloose, Farah Roula, Christelle Dupraz, Evelyne De Bont, Joelle Guilhot, Michael Dworzak, Frédéric Millot, Thierry Leblanc, Françoise Brizard, Andrea Biondi, Srdjana Culic, Krzysztof Kałwak, François Guilhot, Adalet Meral Güneş, Petr Sedlacek, André Baruchel, Birgitte Lausen, Meinolf Suttorp, Chi Kong Li, Emilia Kaiserova
Publikováno v:
Cancer. 123:3609-3616
Background In the adult population with newly diagnosed chronic myeloid leukemia (CML), variant translocations are usually not considered to be impairing the prognosis, whereas some additional cytogenetic abnormalities (ACAs) are associated with a ne
Publikováno v:
Annales de biologie clinique. 75:129-145
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm resulting from the t(9;22)(q34;q11) translocation. It is characterized by the presence of the BCR-ABL1 fusion gene encoding the BCR-ABL oncoprotein characterized by a deregulated tyrosin
Autor:
Sara Basbous, Nathalie Piccirilli, Françoise Brizard, François Guilhot, André Herbelin, Anaïs Levescot, Jean-Marc Gombert, Lydia Roy, Nicolas Bourmeyster
Publikováno v:
The Journal of Pathology. 240:262-268
CD1d-restricted invariant natural killer T (iNKT) cells are believed to play a key role in cancer immune surveillance, and are functionally deficient in patients with chronic myeloid leukaemia (CML). Herein, we have hypothesized that this defect migh
Autor:
Sara, Basbous, Anaïs, Levescot, Nathalie, Piccirilli, Françoise, Brizard, François, Guilhot, Lydia, Roy, Nicolas, Bourmeyster, Jean-Marc, Gombert, André, Herbelin
Publikováno v:
The Journal of pathology. 240(3)
CD1d-restricted invariant natural killer T (iNKT) cells are believed to play a key role in cancer immune surveillance, and are functionally deficient in patients with chronic myeloid leukaemia (CML). Herein, we have hypothesized that this defect migh
Autor:
Maud Voldoire, Ali G. Turhan, Jean-Claude Chomel, Danielle Canioni, Caroline Mayeur-Rousse, Françoise Brizard, Edouard Randriamalala, Nathalie Sorel
Publikováno v:
Leukemia Research. 36:377-381
Autor:
Lydia Roy, Jean-Claude Chomel, Ali G. Turhan, Françoise Brizard, Nathalie Sorel, Angelina Bertrand, Marie-Laure Bonnet, François Guilhot
Publikováno v:
Leukemia & Lymphoma. 51:2103-2111
Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myeloid leukemia (CML). However, resistance is occasionally observed, mainly due to mutations within the BCR-ABL kinase domain. The T315I substitution confers complete res