Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Françoise Boiron-Sargueil"'
Autor:
Bertrand Garbay, Sabine Bauxis-Lagrave, Claude Cassagne, Georgina Elson, Françoise Boiron-Sargueil
Publikováno v:
Developmental Brain Research. 98:197-203
The present study documents the steady-state levels for the mRNAs encoding acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), stearoyl-CoA desaturase (SCD2) and brain long-chain acyl-CoA synthase (BLACS) during mouse development. It is shown th
Publikováno v:
Neurochemistry International. 29:607-622
In vivo glycerolipid metabolism was studied in sciatic nerves of normal and Trembler mice. The results showed that two kinetically independent pathways were implicated in the labeling of diacylglycerophospholipids from [3H]palmitate: the Kennedy path
Publikováno v:
Neuroscience Letters. 198:157-160
The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP22) gene which results in an abnormal myelination of its peripheral nervous system. The recent identification of two different PMP22 mRNA differin
Publikováno v:
Journal of Neurochemistry. 59:652-656
The amidification of sphingosine by acyl donors has been investigated in a microsomal fraction prepared from sciatic nerves of normal and Trembler mice. In the control, a ceramide synthesis is observed in the presence of acyl-CoAs and not with free f
Autor:
Claude Cassagne, Huiyuan Jiang, Bertrand Garbay, Taibi Chbihi, John Kamholz, Françoise Boiron-Sargueil, Michael E. Shy
Publikováno v:
Scopus-Elsevier
We studied the regulation of oleic acid synthesis in the PNS. During mouse postnatal development, the proportion of 18:1 rises in the sciatic nerve from 17% at 5 days of age to 33% at 25 days. However, this rise does not occur in the dysmyelinating m
Autor:
Claude Cassagne, Bertrand Garbay, Jean-Jacques Bessoule, Françoise Boiron-Sargueil, Anthony M. Heape
Publikováno v:
Scopus-Elsevier
Sphingolipid metabolic pathways in the peripheral nerves of dysmyelinating Trembler mice were studied in vivo, using intraneurally injected [3H]palmitate as the exogenous substrate. The kinetic analysis of the experimental data obtained for the mutan
Publikováno v:
Neuroscience letters. 186(1)
The formation of cerebrosides by the galactosylation of ceramides was investigated in a microsomal fraction prepared from sciatic nerves of normal and Trembler mice. In the control, cerebroside synthesis is observed in the presence of uridine-diphosp
Publikováno v:
Neurochemistry international. 13(3)
We report here the presence of a Stearoyl-CoA: [1-palmitoyl]-glycerophosphorylcholine (LPC) transacylase activity in the microsomal fraction of normal and Trembler mouse sciatic nerves. Under the experimental conditions studied as a function of incub